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Research Article

Prevalence and Pattern of Skin Disorders among Human Immuno Deficiency Virus (HIV) Infected Children in Aminu Kano Teaching Hospital (AKTH) Kano, Nigeria

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Introduction: In HIV infected children, skin disorders are important as they serve as clue to diagnosis of the HIV disease. The Skin is one of the early systems affected by HIV/AIDS, which can affect almost all organs and systems in the body. Prevalence of skin disorders among HIV infected children is up to 90% in some studies.
Objective: To determine the prevalence of skin disorders among HIV infected children attending paediatric infectious disease clinic in Aminu Kano Teaching Hospital Kano, Nigeria.

Materials and Methods: A cross-sectional study was conducted to determine the prevalence of skin manifestations among HIV infected children attending paediatric infectious disease clinic of Aminu Kano Teaching Hospital, Kano, Nigeria. A total of 223 HIV infected participants aged 6weeks to14 years were recruited for this study.

Results: The prevalence of skin disorders among HIV infected children was 78.0%. The leading categories were infections and infestations accounting for 55.1% then inflammatory skin disorders (20.6%) Dermatophytoses were the commonest specific skin disorders observed.

Conclusion: Therefore, the prevalence of skin disorder among HIV infected children in Aminu Kano Teaching Hospital is high (78%). Infections and infestations were the commonest category found followed by inflammatory skin disorders.

Yahya Aishatu Muhammad*
Volume2-Issue3 | Received: 2021-03-10 | Accepted: 2021-03-22 | Published: 2021-03-23 | Pages: 201-205

FullText HTML FullText PDF DOI: 10.37871/jbres1211

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Copyright: © 2021 Muhammad YA. Distributed under Creative Commons CC-BY 4.0

How to cite this article: Muhammad YA. Prevalence and Pattern of Skin Disorders among Human Immuno Deficiency Virus (HIV) Infected Children in Aminu Kano Teaching Hospital (AKTH) Kano, Nigeria. J Biomed Res Environ Sci. 2021 Mar 23; 2(3): 201-205. doi: 10.37871/jbres1211, Article ID: jbres1211

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  1. Moir S, Chun TW, Fauci AS. Pathogenic mechanisms of HIV disease. Annu Rev Pathol. 2011;6:223-48. doi: 10.1146/annurev-pathol-011110-130254. PMID: 21034222.
  2. Letvin NL, Walker BD. Immunopathogenesis and immunotherapy in AIDS virus infections. Nat Med. 2003 Jul;9(7):861-6. doi: 10.1038/nm0703-861. PMID: 12835706.
  3. WHO. Global update on the health sector response to HIV. WHO Fact sheet, Geneva, switzerland. 2016.
  4. Saunders R. Equity and access to ART in Ethiopia: Activity report. Washington, DC Futur Group, Heal Policy Initiat Task order 1. 2010.
  5. Lo J, Nwafor SU, Schwitters AM, Mitchell A, Sebastian V, Stafford KA, Ezirim I, Charurat M, McIntyre AF. Key Population Hotspots in Nigeria for Targeted HIV Program Planning: Mapping, Validation, and Reconciliation. JMIR Public Health Surveill. 2021 Feb 22;7(2):e25623. doi: 10.2196/25623. PMID: 33616537; PMCID: PMC7939933.
  6. World Health Organization (WHO) . Global HIV and AIDS statistics-2019 fact sheet. 2019.
  7. Jindal R. The Ages of children and their dermatoses. Clin Paediatr Dermatol. 2016;1:2-4. doi: 10.21767/2472-0143.100003
  8. Hay RJ, Fuller LC. The assessment of dermatological needs in resource-poor regions. Int J Dermatol. 2011 May;50(5):552-7. doi: 10.1111/j.1365-4632.2011.04953.x. PMID: 21506971.
  9. Rodgers S, Leslie KS. Skin infections in HIV-infected individuals in the era of HAART. Curr Opin Infect Dis. 2011 Apr;24(2):124-9. doi: 10.1097/QCO.0b013e328342cb31. PMID: 21169832.
  10. Cedeno-Laurent F, Gómez-Flores M, Mendez N, Ancer-Rodríguez J, Bryant JL, Gaspari AA, Trujillo JR. New insights into HIV-1-primary skin disorders. J Int AIDS Soc. 2011 Jan 24;14:5. doi: 10.1186/1758-2652-14-5. PMID: 21261982; PMCID: PMC3037296.
  11. UNICEF. State of the World’s Children. NEWYORK USA. 2006.
  12. Chu C, Selwyn PA. Complications of HIV infection: a systems-based approach. Am Fam Physician. 2011 Feb 15;83(4):395-406. PMID: 21322514.
  13. El Hachem M, Bernardi S, Pianosi G, Krzysztofiak A, Livadiotti S, Gattinara GC. Mucocutaneous manifestations in children with HIV infection and AIDS. Pediatr Dermatol. 1998 Nov-Dec;15(6):429-34. doi: 10.1046/j.1525-1470.1998.1998015429.x. PMID: 9875963.
  14. Mendiratta V, Mittal S, Jain A, Chander R. Mucocutaneous manifestations in children with human immunodeficiency virus infection. Indian J Dermatol Venereol Leprol. 2010 Sep-Oct;76(5):458-66. doi: 10.4103/0378-6323.69041. PMID: 20826983.
  15. Okechukwu AA, Okechukwu OI, Paul J. Patterns of skin disorder and its relationship with CD4 + cell count in a cohort of HIV-infected children. J Med Med Sci. 2011;2:1131-1138.
  16. Oyedaji GA. Socioeconomic and cultural background of hospitalized children in Ilesa. Nig J Paediatr. 1985;12:11-17.
  17. Umoru D, Oviawe O, Ibadin M, Onunu A, Esene H. Mucocutaneous manifestation of pediatric human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) in relation to degree of immunosuppression: a study of a West African population. Int J Dermatol. 2012 Mar;51(3):305-12. doi: 10.1111/j.1365-4632.2011.05077.x. PMID: 22348567.
  18. Katibi OS, Ogunbiyi AO, Oladokun RE, Ernest SK, Osinusi K, Brown BJ, Adedoyin OT, Ojuawo AI. Mucocutaneous Disorders of Pediatric HIV in South West Nigeria: Surrogates for Immunologic and Virologic Indices. J Int Assoc Provid AIDS Care. 2016 Sep;15(5):423-31. doi: 10.1177/2325957413502540. Epub 2013 Sep 20. PMID: 24056797.
  19. Osinaike BO, Temiye EO, Odusote O, Akinsulie AO, Iroha E. Prevalence of Skin Diseases in Children with Human Immunodeficiency Syndrome Infection in Paediatric HIV Clinic of A Tertiary Hospital in Nigeria. Nig Q J Hosp Med. 2015 Jul-Sep;25(3):164-70. PMID: 27295809.
  20. Lowe S, Ferrand RA, Morris-Jones R, Salisbury J, Mangeya N, Dimairo M, Miller RF, Corbett EL. Skin disease among human immunodeficiency virus-infected adolescents in Zimbabwe: a strong indicator of underlying HIV infection. Pediatr Infect Dis J. 2010 Apr;29(4):346-51. doi: 10.1097/INF.0b013e3181c15da4. PMID: 19940800; PMCID: PMC3428906.
  21. Noel GJ. Host defense abnormalities associated with HIV infection. Pediatr Clin North Am. 1991 Feb;38(1):37-43. doi: 10.1016/s0031-3955(16)38041-5. PMID: 1987517.
  22. Doni SN, Mitchell AL, Bogale Y, Walker SL. Skin disorders affecting human immunodeficiency virus-infected children living in an orphanage in Ethiopia. Clin Exp Dermatol. 2012 Jan;37(1):15-9. doi: 10.1111/j.1365-2230.2011.04202.x. PMID: 22182432.
  23. Ramesh RP, Raghavendra NV, Bhuvaneshwari CY, Ashok VB. Pattern of muco- cutaneous manifestations in HIV infected children at tertiary care hospital, north Karnataka. Int J Contemp Paediatr. 2015;2:419-423. doi: 10.18203/2349-3291.ijcp20150987
  24. Bissek AC, Tabah EN, Kouotou E, Sini V, Yepnjio FN, Nditanchou R, Nchufor RN, Defo D, Dema F, Fonsah JY, Njamnshi AK, Muna WF. The spectrum of skin diseases in a rural setting in Cameroon (sub-Saharan Africa). BMC Dermatol. 2012 Jun 21;12:7. doi: 10.1186/1471-5945-12-7. PMID: 22720728; PMCID: PMC3445843.
  25. Stefanaki C, Stratigos AJ, Stratigos JD. Skin manifestations of HIV-1 infection in children. Clin Dermatol. 2002 Jan-Feb;20(1):74-86. doi: 10.1016/s0738-081x(01)00234-6. PMID: 11849897.
  26. Panya MF, Mgonda YM, Massawe AW. The pattern of mucocutaneous disorders in HIV-infected children attending care and treatment centres in Dar es Salaam, Tanzania. BMC Public Health. 2009;9:234.
  27. Goh BK, Chan RK, Sen P, Theng CT, Tan HH, Wu YJ, Paton NI. Spectrum of skin disorders in human immunodeficiency virus-infected patients in Singapore and the relationship to CD4 lymphocyte counts. Int J Dermatol. 2007 Jul;46(7):695-9. doi: 10.1111/j.1365-4632.2007.03164.x. PMID: 17614796.
  28. Martinez-Rojano H, Morales QC, Torres GF, Gorbea RM. Manifestations of mucocutaneous in HIV-seropositive mothers born children. Pediatr. 2000;67:214-219.
  29. Prose NS. Mucocutaneous disease in pediatric human immunodeficiency virus infection. Pediatr Clin North Am. 1991 Aug;38(4):977-90. doi: 10.1016/s0031-3955(16)38163-9. PMID: 1870913.
  30. Don PC, Shen NN, Koestenblatt EK, Sierra MF, Stone RK, Bamji M. Mucocutaneous fungal colonization in HIV-infected children. Acta Derm Venereol. 1995 Jul;75(4):310-11. doi: 10.2340/0001555575310311. PMID: 8578957.
  31. Carré D, Dompmartin A, Verdon R, Comoz F, Le Brun E, Freymuth F, Leroy D. Epidermodysplasia verruciformis in a patient with HIV infection: no response to highly active antiretroviral therapy. Int J Dermatol. 2003 Apr;42(4):296-300. doi: 10.1046/j.1365-4362.2003.01707_2.x. PMID: 12694498.


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