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Neurotoxicants on the Menu: Mapping the Link between Food Contaminants and Autism in African Children - A Scoping Review

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Open Access
Article Type Review Article
Subject Medicine Group
OCLC JBRES Record
Wilfred AA* and Laure VNN
Issue: Volume6-Issue10
Pages: 1457-1469
Received: 2025-10-11
Accepted: 2025-10-16
Published: 2025-10-18

Abstract

Background: Autism Spectrum Disorder (ASD) is a growing neurodevelopmental concern in Africa, with environmental risk factors such as neurotoxic food contaminants believed to play a role in its prevalence among children.

Objective: This review aims to synthesize evidence linking dietary exposure to neurotoxic food contaminants, such as heavy metals, pesticides and mycotoxins, with ASD risk in African children and to highlight regional exposure patterns, regulatory contexts, and research gaps.

Methods: A systematic search was conducted in PubMed, Scopus, Web of Science, and African regional databases for studies published between 2000 and 2025. Grey literature from WHO and FAO was also included. Eligibility criteria covered African populations, experimental models, and food safety policies addressing neurotoxic exposure and ASD outcomes. Data extraction focused on contaminant types, sources, outcomes, and country-level regulation. Results were synthesized qualitatively to map evidence and identify gaps.

Results: Heavy metals, pesticides, and mycotoxins were frequently identified in staple African foods, with animal and epidemiological studies suggesting higher burdens in children with ASD. The critical exposure periods are prenatal and early childhood. Regulatory and surveillance deficiencies were evident, especially in rural and informal market settings.

Discussion: Widespread exposure to neurotoxicants, combined with weak food safety oversight, increases ASD risk among African children. Evidence is fragmented and underrepresents rural contexts. Multidisciplinary research and robust governance are needed to clarify the exposure-disease link.

Conclusion: Foodborne neurotoxins pose significant risks to ASD in Africa. Enhancing surveillance, regulation, and research, particularly for vulnerable populations, is vital to prevent ASD and protect children's health.

FullText HTML FullText PDF DOI: 10.37871/jbres2202 Crossmark

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© 2025 Wilfred AA, et al. Distributed under Creative Commons CC-BY 4.0 Creative CommonsAttribution

How to cite this article

Abia WA, Ngoungoure LVN. Neurotoxicants on the Menu: Mapping the Link between Food Contaminants and Autism in African Children - A Scoping Review. J Biomed Res Environ Sci. 2025 Oct 14; 6(10): 1457-1469. doi: 10.37871/jbres2202, Article ID: JBRES2202, Available at: https://www.jelsciences.com/articles/ jbres2202.pdf

Subject area(s)

NeurologyPublic HealthNutritionPediatrics

References

  1. Koum DCK, Enyama D, Foko LPK, Noukeu D, Nguedia B, Mbono R, Eposse C, Eboumbou PE, Engome CB, Mapoure YN. Diagnosis and treatment challenges of autism spectrum disorder at a reference hospital in Douala, Cameroon. BMC Pediatr. 2023 Sep 13;23(1):459. doi: 10.1186/s12887-023-04242-4. PMID: 37704945; PMCID: PMC10498515.
  2. Lord C, Brugha TS, Charman T, Cusack J, Dumas G, Frazier T, Jones EJH, Jones RM, Pickles A, State MW, Taylor JL, Veenstra-VanderWeele J. Autism spectrum disorder. Nat Rev Dis Primers. 2020 Jan 16;6(1):5. doi: 10.1038/s41572-019-0138-4. PMID: 31949163; PMCID: PMC8900942.
  3. Zeidan J, Fombonne E, Scorah J, Ibrahim A, Durkin MS, Saxena S, Yusuf A, Shih A, Elsabbagh M. Global prevalence of autism: A systematic review update. Autism Res. 2022 May;15(5):778-790. doi: 10.1002/aur.2696. Epub 2022 Mar 3. PMID: 35238171; PMCID: PMC9310578.
  4. Salari N, Rasoulpoor S, Rasoulpoor S, Shohaimi S, Jafarpour S, Abdoli N, Khaledi-Paveh B, Mohammadi M. The global prevalence of autism spectrum disorder: a comprehensive systematic review and meta-analysis. Ital J Pediatr. 2022 Jul 8;48(1):112. doi: 10.1186/s13052-022-01310-w. PMID: 35804408; PMCID: PMC9270782.
  5. Jiang CC, Lin LS, Long S, Ke XY, Fukunaga K, Lu YM, Han F. Signalling pathways in autism spectrum disorder: mechanisms and therapeutic implications. Signal Transduct Target Ther. 2022 Jul 11;7(1):229. doi: 10.1038/s41392-022-01081-0. PMID: 35817793; PMCID: PMC9273593.
  6. Shenouda J, Barrett E, Davidow AL, Halperin W, Silenzio VMB, Zahorodny W. Prevalence of autism spectrum disorder in a large, diverse metropolitan area: Variation by sociodemographic factors. Autism Res. 2022 Jan;15(1):146-155. doi: 10.1002/aur.2628. Epub 2021 Oct 21. PMID: 34672116; PMCID: PMC8755586.
  7. Morales Hidalgo P, Voltas Moreso N, Canals Sans J. Autism spectrum disorder prevalence and associated sociodemographic factors in the school population: EPINED study. Autism. 2021 Oct;25(7):1999-2011. doi: 10.1177/13623613211007717. Epub 2021 Apr 22. PMID: 33884927.
  8. Bhuiyan MR, Islam MZ, Rafi A. Socio-demographic characteristics and related factors affecting children with autism spectrum disorder. J Armed Forces Med Coll Bangladesh. 2017;13(1):56-61.
  9. Aderinto N, Olatunji D, Idowu O. Autism in Africa: prevalence, diagnosis, treatment and the impact of social and cultural factors on families and caregivers: a review. Ann Med Surg (Lond). 2023 Jul 24;85(9):4410-4416. doi: 10.1097/MS9.0000000000001107. PMID: 37663716; PMCID: PMC10473371.
  10. Adams SN. The Unmasking of Autism in South Africa and Nigeria. Neuropsychiatr Dis Treat. 2024 May 8;20:947-955. doi: 10.2147/NDT.S461650. PMID: 38737770; PMCID: PMC11088825.
  11. Bamford C, Bakariwie AWC, Fatawu RT. A review of the prevalence, diagnosis, treatment, and support resources for autism spectrum disorder in Africa. Int J Adv Biol Biomed Res. 2025;13(4):448-71.
  12. Diagnostic and statistical manual of mental disorders: DSM-5. 5th ed. Washington (DC): American Psychiatric Association. 2013.
  13. Nwokolo EU, Langdon PE, Murphy GH. Screening for intellectual disabilities and/or autism amongst older children and young adults: A systematic review of tools for use in Africa. Rev J Autism Dev Disord. 2024;11(2):384-406.
  14. Kantawala B, Abu-Bakr A, Kasini B, Ndayambaje M, Ian Soh S, Nazir A, Wojtara M, Uwishema O. Exploring the landscape of autism in Africa: challenges in diagnosis, support, and resources - a short communication. Ann Med Surg (Lond). 2023 Oct 2;85(11):5838-5841. doi: 10.1097/MS9.0000000000001376. PMID: 37915637; PMCID: PMC10617929.
  15. Ye BS, Leung AOW, Wong MH. The association of environmental toxicants and autism spectrum disorders in children. Environ Pollut. 2017 Aug;227:234-242. doi: 10.1016/j.envpol.2017.04.039. Epub 2017 May 2. PMID: 28475976.
  16. Cardenas-Iniguez C, Burnor E, Herting MM. Neurotoxicants, the Developing Brain, and Mental Health. Biol Psychiatry Glob Open Sci. 2022 Jul;2(3):223-232. doi: 10.1016/j.bpsgos.2022.05.002. Epub 2022 May 23. PMID: 35911498; PMCID: PMC9337627.
  17. Nehzomi ZS, Shirani K. Investigating the role of food pollutants in autism spectrum disorder: a comprehensive analysis of heavy metals, pesticides, and mycotoxins. Naunyn Schmiedebergs Arch Pharmacol. 2025 Mar;398(3):2511-2533. doi: 10.1007/s00210-024-03551-4. Epub 2024 Oct 28. PMID: 39466439.
  18. Ali MM, Hossain D, Khan MS. Environmental pollution with heavy metals: A public health concern. In: Heavy metals-Their environmental impacts and mitigation. London: IntechOpen. 2021.
  19. Shetty BR, Jagadeesha PB, Salmataj SA. Heavy metal contamination and its impact on the food chain: Exposure, bioaccumulation, and risk assessment. CyTA J Food. 2025;23(1):2438726.
  20. Angon PB, Islam MS, Kc S, Das A, Anjum N, Poudel A, Suchi SA. Sources, effects and present perspectives of heavy metals contamination: Soil, plants and human food chain. Heliyon. 2024 Mar 26;10(7):e28357. doi: 10.1016/j.heliyon.2024.e28357. PMID: 38590838; PMCID: PMC10999863.
  21. Ahmad MF, Ahmad FA, Alsayegh AA, Zeyaullah M, AlShahrani AM, Muzammil K, Saati AA, Wahab S, Elbendary EY, Kambal N, Abdelrahman MH, Hussain S. Pesticides impacts on human health and the environment with their mechanisms of action and possible countermeasures. Heliyon. 2024 Apr 4;10(7):e29128. doi: 10.1016/j.heliyon.2024.e29128. PMID: 38623208; PMCID: PMC11016626.
  22. Kaur R, Choudhary D, Bali S, Bandral SS, Singh V, Ahmad MA, Rani N, Singh TG, Chandrasekaran B. Pesticides: An alarming detrimental to health and environment. Sci Total Environ. 2024 Mar 10;915:170113. doi: 10.1016/j.scitotenv.2024.170113. Epub 2024 Jan 15. PMID: 38232846.
  23. Dhankhar N, Kumar J. Impact of increasing pesticides and fertilizers on human health: A review. Mater Today Proc. 2023.
  24. Khan R. Mycotoxins in food: Occurrence, health implications, and control strategies-A comprehensive review. Toxicon. 2024 Sep;248:108038. doi: 10.1016/j.toxicon.2024.108038. Epub 2024 Jul 22. PMID: 39047955.
  25. Balan B, Dhaulaniya AS, Kumar M. Aflatoxins in food: Prevalence, health effects, and emerging trends in its mitigation - An updated review. Food Saf Health. 2024;2(1):39-71.
  26. Wang L, Wang Q, Wang S, Cai R, Yuan Y, Yue T, Wang Z. Bio-control on the contamination of Ochratoxin A in food: Current research and future prospects. Curr Res Food Sci. 2022 Sep 11;5:1539-1549. doi: 10.1016/j.crfs.2022.09.007. PMID: 36161229; PMCID: PMC9489538.
  27. Kamle M, Mahato DK, Devi S, Lee KE, Kang SG, Kumar P. Fumonisins: Impact on Agriculture, Food, and Human Health and their Management Strategies. Toxins (Basel). 2019 Jun 7;11(6):328. doi: 10.3390/toxins11060328. PMID: 31181628; PMCID: PMC6628439.
  28. Mahato DK, Devi S, Pandhi S, Sharma B, Maurya KK, Mishra S, Dhawan K, Selvakumar R, Kamle M, Mishra AK, Kumar P. Occurrence, Impact on Agriculture, Human Health, and Management Strategies of Zearalenone in Food and Feed: A Review. Toxins (Basel). 2021 Jan 26;13(2):92. doi: 10.3390/toxins13020092. PMID: 33530606; PMCID: PMC7912641.
  29. Deoxynivalenol in food and feed: Occurrence and exposure. EFSA J. 2013;11(10):3379.
  30. Eskola M, Kos G, Elliott CT, Hajšlová J, Mayar S, Krska R. Worldwide contamination of food-crops with mycotoxins: Validity of the widely cited 'FAO estimate' of 25. Crit Rev Food Sci Nutr. 2020;60(16):2773-2789. doi: 10.1080/10408398.2019.1658570. Epub 2019 Sep 3. PMID: 31478403.
  31. Love C, Sominsky L, O'Hely M, Berk M, Vuillermin P, Dawson SL. Prenatal environmental risk factors for autism spectrum disorder and their potential mechanisms. BMC Med. 2024 Sep 16;22(1):393. doi: 10.1186/s12916-024-03617-3. PMID: 39278907; PMCID: PMC11404034.
  32. Zhang X, Mei D, Li Y, You M, Wang D, Yao D, Xu Y, Zhai L, Wang Y. Arsenic exposure via drinking water during pregnancy and lactation induces autism-like behaviors in male offspring mice. Chemosphere. 2022 Mar;290:133338. doi: 10.1016/j.chemosphere.2021.133338. Epub 2021 Dec 17. PMID: 34929279.
  33. Zhou F, Ouyang L, Xie J, Liu S, Li Q, Yang S, Li J, Su R, Rao S, Yan L, Wan X, Cheng H, Liu P, Li L, Zhu Y, Du G, Feng C, Fan G. Co-exposure to low-dose lead, cadmium, and mercury promotes memory deficits in rats: Insights from the dynamics of dendritic spine pruning in brain development. Ecotoxicol Environ Saf. 2023 Oct 1;264:115425. doi: 10.1016/j.ecoenv.2023.115425. Epub 2023 Sep 1. PMID: 37660527.
  34. Zhao ZH, Zheng G, Wang T, Du KJ, Han X, Luo WJ, Shen XF, Chen JY. Low-level Gestational Lead Exposure Alters Dendritic Spine Plasticity in the Hippocampus and Reduces Learning and Memory in Rats. Sci Rep. 2018 Feb 23;8(1):3533. doi: 10.1038/s41598-018-21521-8. PMID: 29476096; PMCID: PMC5824819.
  35. Bertoletti ACC, Peres KK, Faccioli LS, Vacci MC, Mata IRD, Kuyven CJ, Bosco SMD. Early exposure to agricultural pesticides and the occurrence of autism spectrum disorder: a systematic review. Rev Paul Pediatr. 2022 Sep 9;41:e2021360. doi: 10.1590/1984-0462/2023/41/2021360. PMID: 36102405; PMCID: PMC9462403.
  36. Miani A, Imbriani G, De Filippis G, De Giorgi D, Peccarisi L, Colangelo M, Pulimeno M, Castellone MD, Nicolardi G, Logroscino G, Piscitelli P. Autism Spectrum Disorder and Prenatal or Early Life Exposure to Pesticides: A Short Review. Int J Environ Res Public Health. 2021 Oct 19;18(20):10991. doi: 10.3390/ijerph182010991. PMID: 34682738; PMCID: PMC8535369.
  37. Di Re J, Koff L, Avchalumov Y, Singh AK, Baumgartner TJ, Marosi M, Matz LM, Hallberg LM, Ameredes BT, Seeley EH, Buffington SA, Green TA, Laezza F. Environmental exposure to common pesticide induces synaptic deficit and social memory impairment driven by neurodevelopmental vulnerability of hippocampal parvalbumin interneurons. J Hazard Mater. 2025 Mar 5;485:136893. doi: 10.1016/j.jhazmat.2024.136893. Epub 2024 Dec 16. PMID: 39706027; PMCID: PMC11970102.
  38. Curtis MA, Dhamsania RK, Branco RC, Guo JD, Creeden J, Neifer KL, Black CA, Winokur EJ, Andari E, Dias BG, Liu RC, Gourley SL, Miller GW, Burkett JP. Developmental pyrethroid exposure causes a neurodevelopmental disorder phenotype in mice. PNAS Nexus. 2023 Apr 25;2(4):pgad085. doi: 10.1093/pnasnexus/pgad085. PMID: 37113978; PMCID: PMC10129348.
  39. López-Merino E, Cuartero MI, Esteban JA, Briz V. Perinatal exposure to pesticides alters synaptic plasticity signaling and induces behavioral deficits associated with neurodevelopmental disorders. Cell Biol Toxicol. 2023 Oct;39(5):2089-2111. doi: 10.1007/s10565-022-09697-2. Epub 2022 Feb 8. PMID: 35137321; PMCID: PMC10547633.
  40. Banczerowski-Pelyhe I, Banczerowski P, Varro P, Vilagi I. Prenatal dietary fumonisin B1 exposure may modify learning processes in rat offspring. Cereal Res Commun. 2008;36:1947-1950.
  41. Mohamed Fel B, Zaky EA, El-Sayed AB, Elhossieny RM, Zahra SS, Salah Eldin W, Youssef WY, Khaled RA, Youssef AM. Assessment of Hair Aluminum, Lead, and Mercury in a Sample of Autistic Egyptian Children: Environmental Risk Factors of Heavy Metals in Autism. Behav Neurol. 2015;2015:545674. doi: 10.1155/2015/545674. Epub 2015 Oct 5. PMID: 26508811; PMCID: PMC4609793.
  42. Khaled EM, Meguid NA, Bjørklund G, Gouda A, Bahary MH, Hashish A, Sallam NM, Chirumbolo S, El-Bana MA. Altered urinary porphyrins and mercury exposure as biomarkers for autism severity in Egyptian children with autism spectrum disorder. Metab Brain Dis. 2016 Dec;31(6):1419-1426. doi: 10.1007/s11011-016-9870-6. Epub 2016 Jul 13. PMID: 27406246.
  43. Elsheshtawy E, Tobar S, Sherra K. Study of some biomarkers in hair of children with autism. Middle East Curr Psychiatry. 2011;18(1):6-10.
  44. El-baz F, Elhossiny RM, Elsayed AB. Hair mercury measurement in Egyptian autistic children. Egypt J Med Hum Genet. 2010;11(2):135-141.
  45. Nyanza EC, Mhana RJ, Asori M, Thomas DSK, Kisoka AP. Effects of prenatal lead, mercury, cadmium, and arsenic exposure on children's neurodevelopment in an artisanal small-scale gold mining area in Northwestern Tanzania using a multi-chemical exposure model. PLOS Glob Public Health. 2025 Apr 30;5(4):e0004577. doi: 10.1371/journal.pgph.0004577. PMID: 40305519; PMCID: PMC12043129.
  46. Blaurock-Busch E, Nwokolo C. Heavy metals and trace elements in blood, hair and urine of Nigerian children with autistic spectrum disorder. Int Res J Public Health. 2018;2(13).
  47. Omotosho IO, Akinade AO, Lagunju IA, Yakubu MA. Oxidative stress indices in ASD children in Sub-Sahara Africa. J Neurodev Disord. 2021 Oct 19;13(1):50. doi: 10.1186/s11689-021-09379-w. PMID: 34666671; PMCID: PMC8524989.
  48. Kapeleka JA, Sauli E, Sadik O, Ndakidemi PA. Biomonitoring of Acetylcholinesterase (AChE) Activity among Smallholder Horticultural Farmers Occupationally Exposed to Mixtures of Pesticides in Tanzania. J Environ Public Health. 2019 Sep 11;2019:3084501. doi: 10.1155/2019/3084501. PMID: 31611921; PMCID: PMC6755286.
  49. Mwakalasya WN, Mamuya SH, Manji K, Moen BE, Ngowi AV. Neurodevelopment in children born to women exposed to pesticides during pregnancy. medRxiv. 2025;20:05.
  50. Chilipweli PM, Ngowi AV, Manji K. Maternal pesticide exposure and child neuro-development among smallholder tomato farmers in the southern corridor of Tanzania. BMC Public Health. 2021 Jan 20;21(1):171. doi: 10.1186/s12889-020-10097-6. PMID: 33472592; PMCID: PMC7818734.
  51. Fuhrimann S, Farnham A, Staudacher P, Atuhaire A, Manfioletti T, Niwagaba CB, Namirembe S, Mugweri J, Winkler MS, Portengen L, Kromhout H, Mora AM. Exposure to multiple pesticides and neurobehavioral outcomes among smallholder farmers in Uganda. Environ Int. 2021 Jul;152:106477. doi: 10.1016/j.envint.2021.106477. Epub 2021 Mar 20. PMID: 33756429.
  52. Chetty-Mhlanga S, Fuhrimann S, Basera W, Eeftens M, Röösli M, Dalvie MA. Association of activities related to pesticide exposure on headache severity and neurodevelopment of school-children in the rural agricultural farmlands of the Western Cape of South Africa. Environ Int. 2021 Jan;146:106237. doi: 10.1016/j.envint.2020.106237. Epub 2020 Nov 7. PMID: 33171379.
  53. Sá SVM, Monteiro C, Fernandes JO, Pinto E, Faria MA, Cunha SC. Emerging mycotoxins in infant and children foods: A review. Crit Rev Food Sci Nutr. 2023;63(12):1707-1721. doi: 10.1080/10408398.2021.1967282. Epub 2021 Sep 6. PMID: 34486889.
  54. De Santis B, Raggi ME, Moretti G, Facchiano F, Mezzelani A, Villa L, Bonfanti A, Campioni A, Rossi S, Camposeo S, Soricelli S, Moracci G, Debegnach F, Gregori E, Ciceri F, Milanesi L, Marabotti A, Brera C. Study on the Association among Mycotoxins and other Variables in Children with Autism. Toxins (Basel). 2017 Jun 29;9(7):203. doi: 10.3390/toxins9070203. PMID: 28661468; PMCID: PMC5535150.
  55. De Santis B, Brera C, Mezzelani A, Soricelli S, Ciceri F, Moretti G, Debegnach F, Bonaglia MC, Villa L, Molteni M, Raggi ME. Role of mycotoxins in the pathobiology of autism: A first evidence. Nutr Neurosci. 2019 Feb;22(2):132-144. doi: 10.1080/1028415X.2017.1357793. Epub 2017 Aug 10. PMID: 28795659.
  56. Arce-López B, Lizarraga E, López de Mesa R, González-Peñas E. Assessment of Exposure to Mycotoxins in Spanish Children through the Analysis of Their Levels in Plasma Samples. Toxins (Basel). 2021 Feb 15;13(2):150. doi: 10.3390/toxins13020150. PMID: 33672088; PMCID: PMC7919644.
  57. Okoth SA, Ohingo M. Dietary aflatoxin exposure and impaired growth in young children from Kisumu District, Kenya: Cross sectional study. Afr J Health Sci. 2004;11(1-2):43-54. PMID: 17298116.
  58. Khlangwiset P, Shephard GS, Wu F. Aflatoxins and growth impairment: a review. Crit Rev Toxicol. 2011 Oct;41(9):740-55. doi: 10.3109/10408444.2011.575766. Epub 2011 Jun 28. PMID: 21711088.
  59. Stiles J, Jernigan TL. The basics of brain development. Neuropsychol Rev. 2010 Dec;20(4):327-48. doi: 10.1007/s11065-010-9148-4. Epub 2010 Nov 3. PMID: 21042938; PMCID: PMC2989000.
  60. Ismail A, Naeem I, Gong YY. Early life exposure to dietary aflatoxins, health impact and control perspectives: A review. Trends Food Sci Technol. 2021;112:212-224.
  61. Bates MN. Heavy metal exposure and its association with neurodevelopmental disorders in African children: a systematic review. Environ Health Perspect. 2018;126(10):105001.
  62. Exposure to lead: A major public health concern. World Health Organization. 2010.
  63. Iqbal SZ. Occurrence of mycotoxins in food and their impact on human health in developing countries: A review. Food Chem Toxicol. 2019;130:110822.
  64. Wild CP. Aflatoxin, mycotoxins, and children's health in Africa. J Health Environ Res. 2015;1(2):24-30.
  65. Abia WA, Foupouapouognigni Y, Nfombouot HPN. A scoping review on mycotoxin-induced neurotoxicity. Discover Toxicol. 2025;2(1):1.
  66. Ngoungoure LVN, Abia WA, Owona BVA, Foupouapouognigni Y, Elombo FK, Nfombouot HPN, Ntungwe EN, Njayou FN, Tchana AN, Moundipa PF. Neurodevelopmental Outcomes of Mycotoxins Exposure and Effect on Brain Development in Infants and Young Children. Dev Neurobiol. 2025 Oct;85(4):e23000. doi: 10.1002/dneu.23000. PMID: 40898788.
  67. Grace D, Kang'ethe E, Bonfoh B. Food safety policy in 9 African countries. Nairobi, Kenya: ILRI. 2014.
  68. Food safety challenges in Africa. FAO/WHO Regional Conference on Food Safety for Africa. 2007.
  69. Kimanya ME. Contextual interlinkages and authority levels for strengthening coordination of national food safety control systems in Africa. Heliyon. 2024 Apr 26;10(9):e30230. doi: 10.1016/j.heliyon.2024.e30230. PMID: 38726125; PMCID: PMC11078866.
  70. African Union adopts the statute for the establishment of a continental food safety agency. African Union. 2025.
  71. Ayalew A, Sintayehu W, Chunga-Sambo W, Edeme J. Perspective on the new Africa Food Safety Agency. NPJ Sci Food. 2025 May 9;9(1):70. doi: 10.1038/s41538-025-00427-6. PMID: 40346088; PMCID: PMC12064735.
  72. Akeredolu A. Challenges of environmental law enforcement in Nigeria: a case study of Lagos state. J Environ Law. 2020;32(3):445-460.
  73. EHS regulatory developments in South Africa. Enhesa Insights. 2019.
  74. FAO/WHO regional conference on food safety for Africa. 2017.
  75. Ayalew A, Kareem FO, Grace D. A paradigm shift in food safety for Africa. AU Food Safety Strategy. 2022.
  76. Pradeilles R, Irache A, Wanjohi MN, Holdsworth M, Laar A, Zotor F, Tandoh A, Klomegah S, Graham F, Muthuri SK, Kimani-Murage EW, Coleman N, Green MA, Osei-Kwasi HA, Bohr M, Rousham EK, Asiki G, Akparibo R, Mensah K, Aryeetey R, Bricas N, Griffiths P. Urban physical food environments drive dietary behaviours in Ghana and Kenya: A photovoice study. Health Place. 2021 Sep;71:102647. doi: 10.1016/j.healthplace.2021.102647. Epub 2021 Aug 7. PMID: 34375838; PMCID: PMC8520917.
  77. Ramaboli MC, Ocvirk S, Khan Mirzaei M, Eberhart BL, Valdivia-Garcia M, Metwaly A, Neuhaus K, Barker G, Ru J, Nesengani LT, Mahdi-Joest D, Wilson AS, Joni SK, Layman DC, Zheng J, Mandal R, Chen Q, Perez MR, Fortuin S, Gaunt B, Wishart D, Methé B, Haller D, Li JV, Deng L, Swart R, O'Keefe SJD. Diet changes due to urbanization in South Africa are linked to microbiome and metabolome signatures of Westernization and colorectal cancer. Nat Commun. 2024 Apr 20;15(1):3379. doi: 10.1038/s41467-024-46265-0. PMID: 38643180; PMCID: PMC11032404.
  78. Oken E, Bellinger DC. Mycotoxins in food: A silent epidemic in Africa. Environ Health Perspect. 2008;116(12):A512.
  79. Lead poisoning and health. World Health Organization. 2018.
  80. Thabane L. Prevalence of autism spectrum disorder in Africa: A systematic review and meta-analysis. J Autism Dev Disord. 2020;50(12):4380-4395.
  81. Landrigan PJ, Fuller R, Acosta NJR, Adeyi O, Arnold R, Basu NN, Baldé AB, Bertollini R, Bose-O'Reilly S, Boufford JI, Breysse PN, Chiles T, Mahidol C, Coll-Seck AM, Cropper ML, Fobil J, Fuster V, Greenstone M, Haines A, Hanrahan D, Hunter D, Khare M, Krupnick A, Lanphear B, Lohani B, Martin K, Mathiasen KV, McTeer MA, Murray CJL, Ndahimananjara JD, Perera F, Potočnik J, Preker AS, Ramesh J, Rockström J, Salinas C, Samson LD, Sandilya K, Sly PD, Smith KR, Steiner A, Stewart RB, Suk WA, van Schayck OCP, Yadama GN, Yumkella K, Zhong M. The Lancet Commission on pollution and health. Lancet. 2018 Feb 3;391(10119):462-512. doi: 10.1016/S0140-6736(17)32345-0. Epub 2017 Oct 19. Erratum in: Lancet. 2018 Feb 3;391(10119):430. doi: 10.1016/S0140-6736(17)32817-9. PMID: 29056410.
  82. Fombonne E. Epidemiology of autism spectrum disorders in African populations: A review. Autism Res. 2020;13(8):1251-1262.
  83. The state of food and agriculture 2019. Moving forward on food safety. Rome: Food and Agriculture Organization of the United Nations. FAO. 2019.
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