Pharmacology
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PharmacologyThese topics are filtered from our journals helping to discover the community within the widespread of multi-disciplinary Have a look at this page once and make your article more discoverable in our esteemed journal to ensuring readers find your article through search engines such as Google.
Research Articles
52 articles
Open Access
Review Article 22 Apr 2026
Therapeutic Strategies in Acute Myeloid Leukemia: Current Advances and Future Directions
Acute Myeloid Leukemia (AML) is a clinically aggressive and molecularly heterogeneous hematologic malignancy characterized by poor long-term outcomes, largely due to high rates of relapse and therapeutic resistance. For …
46 Views 56 Downloads
Open Access
31 Mar 2026
Combined Dopaminergic Drugs to Treat Pyoderma Gangrenosum
Monoclonal antibody therapy directed against certain pathways leading to the eventual cellular immune reaction to an irritating agent has been a mainstay of therapy for many pathological conditions considered autoimmune …
39 Views 51 Downloads
Open Access
Research Article 09 Mar 2026
Formulation Development, Analytical Validation and In vitro Assessment of a Generic Lymecycline 408 mg Hard Capsule
This study documents the stepwise development and evaluation of a generic Lymecycline 408 mg hard gelatin capsule manufactured locally in Pakistan. The formulation process began with the selection of suitable pharmacopei…
32 Views 62 Downloads
Open Access
Research Article 03 Feb 2026
Coenzyme Q10 Nanoemulsions Enhance Bioavailability in Drosophila Melanogaster Larvae
Coenzyme Q10 (CoQ10) is a vital lipophilic molecule involved in mitochondrial energy production and antioxidant defense mechanisms. Despite its therapeutic potential in aging, cardiovascular, and neurodegenerative diseas…
25 Views 95 Downloads 1 Citation
Open Access
Letter 20 Jan 2026
Poly-De-Prescribing to Treat the Iatrogenic Epidemic of Polypharmacy - A Major Public Health Challenge
49 Views 69 Downloads
Open Access
Research Article 08 Nov 2025
Refluward® HA: Efficacy and Safety in Patients with Gastro-Esophageal Diseases
The physiological activity of stomach and esophagus is often impaired by the onset of various diseases such as Gastroesophageal Reflux Disease (GERD), esophagitis, hiatal hernia, tertiary esophageal waves, Barrett’s es…
140 Views 77 Downloads
Open Access
Perspective 23 Oct 2025
Quercetin Analogs as Cancer Chemopreventive Agents: A New Perspective
Quercetin is a flavonoid-type chemical molecule found in many people's daily diets. Previous research has shown that quercetin offers a range of benefits, including anti-inflammatory, antioxidant, and cancer-prevention p…
817 Views 80 Downloads
Open Access
Research Article 30 Sep 2025
Knowledge Attitude and Practice to awards Food Drug Interaction among Health Care Providers at Public Primary Hospitals of Southern Ethiopia
Background: Interactions between food and medications can greatly impact patient adherence and the overall effectiveness of drug therapy. In healthcare settings, Food-Drug Interactions (FDIs) are an increasing concern. V…
171 Views 88 Downloads
Open Access
Mini Review 04 Sep 2025
Bioactive Compounds in Anti-Inflammatory Prevention
Spices and flavorings have been used as food since ancient times and also as medicines and food preservatives in recent decades. Many spices-such as clove, oregano, thyme, cinnamon, and cumin-have been used to treat infe…
676 Views 77 Downloads
Open Access
Research Article 27 Aug 2025
NUVATUL-MZ Ointment for the Treatment of Ganglion Cyst
The most frequent soft tissue masses in the hand and wrist are ganglion cysts, which are the reason for a large portion of orthopaedic and hand surgery clinic appointments. Although these cysts are usually benign, they c…
1,005 Views 92 Downloads
Open Access
Review Article 31 Jul 2025
Role of Cyclooxygenase-2 Inhibitors in Animal Models of Epilepsy: A Systematic Review
Background: The presence of recurrent seizures characterizes epilepsy, which is defined as a chronic disorder of the nervous system. It has recently been suggested that COX-2 inhibitors may offer protective neurotherapeu…
531 Views 105 Downloads
Open Access
Original Article 28 Jul 2025
Molecular Investigation of Cytochrome P-450 Enzymes Inductors
Cytochrome P-450 enzymes play a critical role in xenobiotic metabolism and homeostasis, with their induction offering therapeutic potential for liver diseases and metabolic disorders. Using molecular docking and statisti…
258 Views 81 Downloads
Open Access
Clinical Study 27 Jul 2025
A Clinical Study to Assess the Safety and Pharmacokinetics of Orally Administered Strontium L-lactate in Healthy Adults
Purpose: Strontium salts may provide support for bone health and treatment for osteoporosis, but the safety and effectiveness of these salts is not completely understood. The aim of this clinical study (NCT03761979) was …
393 Views 70 Downloads
Open Access
Original Article 09 Jul 2025
Evaluation of the Effect of Ligaria cuneifolia Infusion on Plasma Cholesterol and Liver and Kidney Function in Patients with Cardiovascular Risk
Ligaria cuneifolia (R. et P.) Tiegh. –Loranthaceae– (Lc), commonly used in traditional medicine, is believed to reduce total plasma cholesterol (TC) and improve blood flow. Objective: To evaluate the effect of inges…
23 Views 83 Downloads
Open Access
Perspective 30 Jun 2025
Trans - Resveratrol as a Food Ingredient Safety Assessment
Resveratrol is a polyphenolic compound naturally found in various plants, notably in red grapes, and initially isolated from the roots of white hellebore. Due to its potential health-promoting properties, it has gained i…
3,568 Views 87 Downloads 1 Citation
Open Access
Review Article 17 May 2025
The Role of Translation Initiation Regulation in Tumorigenesis, Progression and Drug Resistance
The initiation of mRNA translation plays a pivotal role in gene expression and has profound implications for tumorigenesis, tumor progression, and drug resistance. eIF4F complex, as an important part of the classical tra…
2,113 Views 87 Downloads
Open Access
Review Article 28 Feb 2025
Mushrooms Natural Products Cosmetic Weapons as Anti-Hair Loss, Anti-Ageing Skin and Future Prospect
Throughout old history, mushrooms are considered a rich source of many important phytonutrients such as polysaccharides and other nutrients, in addition to many essential amino acids, which are building blocks of vital p…
8,978 Views 94 Downloads 1 Citation
Open Access
Short Communication 30 Nov 2024
Platelet Aggregation Modulation by a Cholesterol Derivative identified in Skin Secretions from Arabian Gulf Catfish (Arius bilineatus, Val.)
We present in this study that one Oxysterol (OS) within the lipid fraction of the isolated epidermal gel released from freshly caught catfish from the Arabian Gulf (Arius bilineatus, Val.) potently and selectively inhibi…
298 Views 111 Downloads
Open Access
Descriptive Research 10 Nov 2024
Pharmacological Evaluation of Atranorin: A Comprehensive Study on its Biological Activities
Lichens are a rich source of diverse secondary metabolites, with depsides playing a crucial role in their biological properties. Atranorin, a prominent depside, has been widely studied due to its significant pharmacologi…
940 Views 118 Downloads 2 Citations
Open Access
Original Article 25 Oct 2024
Comparative Analysis of Red and White Honeys Antimicrobial Activity against Specific Bacterial and Fungal Strains
Honeys popularity as a treatment is growing by the day, with many societies emphasizing its importance and its role in infections causing burns and wounds and recently gets focus from the medical community; as antimicrob…
513 Views 108 Downloads
Open Access
Research Article 20 Sep 2024
Exploring the Potential of Xanthatin from Cuban Xanthium strumarium: Isolation, Characterization, and Biological Evaluation
Xanthatin possesses anticancer activities through its effect on cancer cell proliferation, apoptosis and metastasis In vitro and In vivo. Here, we described the isolation procedure, characterization and In vitro biologic…
351 Views 111 Downloads 2 Citations
Open Access
Short Communication 11 Sep 2024
Prophylaxis by Administration of Stable Iodine: Principle, Evolution and Recommendations
Prophylaxis by stable iodine “KI 65 mg, breakable tablet†is a pharmacological countermeasure of radiological protection adapted for the prevention of thyroid cancer after exposure to radioactive iodine. A first modi…
985 Views 91 Downloads
Open Access
Review Article 10 Aug 2024
Plants from South America: A Systematic Review of Their Antiplasmodial and Antimalarial Activities Based on Ethnopharmacological Use
Malaria remains one of the most important diseases in the world, being lethal to 610 thousand individuals annually. The widespread resistance of P. falciparum to antimalarials emphasizes the urgent need for new therapies…
353 Views 63 Downloads 2 Citations
Open Access
Research Article 05 Aug 2024
Mechanistic Insights into the Anti-Osteoporotic Effects of Naringin via Network Pharmacology and Molecular Docking Studies
Background: Naringin, a natural flavonoid prevalent in citrus fruits, is known for its antioxidant, anti-inflammatory, and antitumor properties. Recent studies suggest its potential influence on bone metabolism, proposin…
565 Views 64 Downloads 1 Citation
Open Access
Research Article 14 Jun 2024
Experience on Utilization of Novel Modeling & Simulation Approaches in Generic Product Development
Modeling and simulation approaches such as Physiologically Based Pharmacokinetic (PBPK) and Physiologically Based Biopharmaceutics Modeling (PBBM) are gaining importance due to their impact to transform drug development …
789 Views 99 Downloads 4 Citations
Open Access
Research Article 22 May 2024
Punica granatum Bioactive Compounds-Loaded Chitosan Nanoparticles Exhibit Potent Antihyperglycemic Effect in Alloxan-Induced Diabetic Mice
In the current study, alloxan-induced diabetic mice model was used to assess the antihyperglycemic effects of Chitosan Nanoparticles (CSNP) loaded with (Punica granatum methanol extract-PG) bioactive compounds. Analysis …
435 Views 110 Downloads 1 Citation
Open Access
Review Article 30 Apr 2024
Most Chronic Medical Conditions in Women are related to Increased Cellular Permeability and most can be Effectively Treated with Dopaminergic Drugs
Based on a conglomeration of basic science research studies a model of hypothetical mechanisms of how the fetal semi-allograft can develop into a live baby was created. One of the tenets of the model is that it is necess…
640 Views 109 Downloads 2 Citations
Open Access
Research Article 29 Feb 2024
Antibacterial Effect of Indian Gooseberry (Phyllanthus emblica L.) Extract Against ESBL Producing Multi-Drug Resistant Bacteria
The most celebrating fruit in Indian traditional medicine Ayurveda is the Indian gooseberry also known as amla fruit, used the prevention of numerous diseases. No reports are available on the prevention of ESBL produced …
5,374 Views 130 Downloads 3 Citations
Open Access
Review Article 15 Feb 2024
Drug Design Strategies, Modes of Action, Synthesis and Industrial Challenges Behind Trifluoromethylated New Chemical Entities
Medicinal plants have been an inspiration source for developing new chemical entities, providing diverse chemical structures and modes of action for medicinal chemistry strategies. Modern medicinal chemistry approaches p…
30,342 Views 120 Downloads 5 Citations
Open Access
Editorial 08 Feb 2024
Tapering as a Progressive Strategy: The Need for Policy Changes to Fund a Promising Addiction Treatment
With the recent rise of drug use such as heroin, benzodiapenes, and xylazine, substance misuse has increasingly affected millions of individuals across the globe. The opioid crisis in particular is a major concern that p…
1,365 Views 123 Downloads
Open Access
Brief Communication 15 Jan 2024
Auctox A New Method to Evaluate the Safety of Anticancer Drugs
The evaluation of anticancer drugs safety is currently based on considering the worst Adverse Event (AE) in a particular patient. The aim of the study was to define a new method which would better describe the impact of …
652 Views 116 Downloads
Open Access
Research Article 17 Nov 2023
Network Pharmacology Study of Huangqi-Huangjing in the Treatment of Diabetic Nephropathy and Diabetic Cardiomyopathy
Objective: To systematically investigate the mechanism of Huangqi-Huangjing in the treatment of Diabetic Nephropathy (DN) and Diabetic Cardiomyopathy (DC) using network pharmacology and molecular docking analysis. To pro…
1,218 Views 121 Downloads
Open Access
Research Article 10 Aug 2023
Ultrasonic-Assisted Extraction of Bioactive Compounds from Elecampagne (Inula helenium, Radix Inulae)
In this study, we had developed a method of ultrasound assisted extraction from Elecampane in order to obtain, identify and the dosing the main bioactive compounds from plant, such as: alantolactone and isoalantolactone,…
1,981 Views 102 Downloads 1 Citation
Open Access
Opinion 26 Jul 2023
Artificial Intelligence in Drug Discovery and Delivery: Advancements and Applications
Artificial Intelligence (AI) has made significant progress in drug discovery and drug delivery and has become an active area of research. The use of AI in drug delivery has gained significant attention, with the developm…
987 Views 100 Downloads 3 Citations
Open Access
Review Article 07 Mar 2023
A Systematic Review of Intravenous Psychoactive Drug Use among Adolescent Females
Background: In the twenty-first century, female adolescents’ use of intravenous psychoactive substances has become widespread worldwide. For instance, statistics show that 155 and 250 million people between the ages of…
447 Views 43 Downloads
Open Access
Opinion 30 Sep 2022
Pharmacovigilance in Jordan
Jordan Food and Drug Administration (JFDA) is an independent institution responsible for protecting the Jordanian public health through ensuring the safety, efficacy, and security of medicines and health technologies, as…
3,318 Views 75 Downloads
Open Access
Review Article 30 Jul 2022
Studies on the Anti-Pulmonary Fibrotic Effect of FGF-2-Targeting Binding Peptide G8
In our previous research, all the data showed that FGF-2 was very possible to be a new target for inhibiting lung fibrosis. Therefore, we plan to find the specific and small peptides to block FGF-2 signaling, hoping to d…
1,395 Views 86 Downloads
Open Access
Research Article 21 May 2022
NMN Nicotinamide Mononucleotide Activates Intracellular Energy and Approaches the Prevention and Improvement of Aging
Aging was defined as one of the diseases by ICD-11. Preventing aging may avoid the risk of various diseases. However, it is difficult to simply prevent aging in daily life. The presence of nutrients is essential there. T…
3,706 Views 112 Downloads
Open Access
Short Communication 30 Apr 2022
Revisiting and Updating Cyanorona-20: The Selective SARS-CoV-2 Inhibitor
Evident inhibition/blockade of the viral RNA-dependent RNA polymerase (RdRp) of the newly-emerged fatal Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is considered one of the most promising and efficient a…
4,516 Views 97 Downloads 1 Citation
Open Access
Review Article 11 Mar 2022
Epigenetic Strategies to Discover Novel Fungal Secondary Metabolites
Natural product search is an enduring revitalization upon the exploration of a huge already exotic potential for Secondary Metabolite (SM) production obscure in microbial genomes.Filamentous fungi genomes have an immense…
2,974 Views 87 Downloads 5 Citations
Open Access
Research Article 24 Feb 2022
Evaluation of South African Equisetum arvense as an Antidiabetic, Antioxidant and Immune Booster using Economical Thin Layer Chromatography Bio-autography
Introduction: Equisetum arvense (E. arvense) is an herbal medicinal plant that is mostly found in Limpopo and the North West Provinces of South Africa. Traditionally, the infusions and decoction of this plant are used in…
1,732 Views 90 Downloads 2 Citations
Open Access
Opinion 24 Feb 2022
Importance of Organophosphorus Compounds in Medicinal Chemistry Field
Organophosphorus chemistry has a crucial role in the field of drug research [1]. As generally well known, the Adenosine Triphosphate (ATP) plays a key role in the energy processes in all living cells of mammals. There ar…
2,583 Views 89 Downloads 7 Citations
Open Access
Retrospective Cohort Study 29 Nov 2021
Pharmacotherapy of Different Tuberculosis Patients its Analysis and Outcomes: A Retrospective Cohort Study
This study aim was to evaluate the prescribed therapies and to identify various drug-related problems as well as their causes in different TB patients admitted at the Pulmonology Department, Northwest General Hospital an…
1,491 Views 79 Downloads 1 Citation
Open Access
Research Article 23 Nov 2021
Evaluation of Antimicrobial Activity of Acacia etbaica Water Extract Leafs against Some Pathogenic Microorganisms
The antimicrobial activity about water extract of Acacia etbaica was examined by using agar well diffusion methods against five gram-positive and negative bacteria[Staphylococcus aureus (ATCC653-8), Pseudomonas aeruginos…
1,588 Views 82 Downloads 2 Citations
Open Access
Review Article 20 Nov 2021
Stemphylium and Ulocladium between Benefit and Harmful
Background: Emerging of microbial resistance, spread of life-threatening diseases, and biological control of pathogens destroying economically important crops, are serious problems that encourage scientists to search for…
2,719 Views 68 Downloads 1 Citation
Open Access
Review Article 30 Sep 2021
Mathematical Modelling of the Addiction of Drug Substances among Students in Tertiary Institutions in Nigeria
In this paper, we formulated a mathematical model for the addiction of drug substances among students in the tertiary institutions in Nigeria. The model explains the dynamics of the use and the addiction of certain subst…
1,853 Views 77 Downloads
Open Access
Original Article 16 Apr 2021
Phytochemical Analysis and Anticancer Activity of Azadirachta Indica Ethanolic Extract against A549 Human Lung Cancer Cell Line
Azadirachta indica phytochemicals are found to have against malignant growth and hostile to bacterial properties. In the specific examination, the coupling proficiency of five mixes that are available in the Azadirachta …
2,891 Views 114 Downloads 5 Citations
Open Access
Review Article 22 Dec 2020
Pharmacodynamics of Remdesivir: How to Improve for COVID-19 Treatment
Potential clinical benefit in SARS-CoV-2 with remdesivir have been noticed. Recently, FDA has granted the use of remdesivir for COVID-therapy. However, the efficacy of remdesivir alone or with combination of other antivi…
8,640 Views 486 Downloads 2 Citations
Open Access
Review Article 23 Nov 2020
The Kinetics of Glucose Transport in Human Red Blood Cells Depend on Their Metabolic State
This article about freshly drawn human red blood cells offers new insights in regulation of glucose transport. Transport of glucose in Glut1 red blood cells is highly asymmetric and depend on metabolic energy, most proba…
6,335 Views 591 Downloads 1 Citation
Open Access
Original Article 31 Oct 2020
Repurposing Potential of Diminazene Aceturate as an Inhibitor of the E. coli DNA Gyrase B
Drug-resistant Escherichia coli (E. coli) has overburdened the healthcare facilities in recent years and is getting hard to combat, mandating search for novel therapeutics with a broad antibacterial spectrum and high che…
3,612 Views 384 Downloads 1 Citation
Open Access
Research Article 15 Sep 2020
Ginger (Zingiber officinale) and its Bioactive Components with Protective and Therapeutic Potential against Cancer
Ginger can be an important complementary medicine for prevention and treatment of different types of cancers, owing to its natural origin, safety, and low cost relative to synthetic cancer drugs. Ginger contains volatile…
5,339 Views 497 Downloads 3 Citations
Open Access
Research Article 22 Jun 2020
Antibiogram Pattern of Potential Pathogenic Bacteria Associated with Domestic Dog Faecal Matter in Port Harcourt Metropolis
This study was aimed at investigating the Antibiogram pattern of Potential Pathogenic Bacteria that are associated with Domestic dog faecal matter in Port Harcourt Metropolis. Convenient sampling techniques were explored…
6,874 Views 827 Downloads 1 Citation
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