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Pathology

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23 Articles Open Access Medicine Group Submit to this Topic
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Medicine Group Cancer & Oncology Research
Related Topics in this Section
Cancer 53 Oncology 49 Radiation Therapy 14 Immunotherapy 10

Research Articles

23 articles
Open Access Research Article 29 Apr 2026

Down-Regulation of Ephrin-B1 in Left Ventricular Non-Compaction

Andrea Frustaci*, Antonio Russo M , Alessandro De Luca, Davide Scarselli, Maria Cecilia D Asdia Aurora Polvani, Emanuela Frustaci, Manuel Belli, Luigi Sansone, Nicola Galea, Livia Marchitelli and Romina Verardo
Background: Left Ventricular Non-Compaction (LVNC) is a rare cardiomyopathy with incompletely understood pathophysiological mechanisms. Ephrin-B1 (Ep), a key protein of cardiomyocyte lateral junctions, may play a role in…
Vol.7, Issue 4 10.37871/jbres2296 ISSN: 2766-2276
34 Views 54 Downloads
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Open Access Research Article 28 Feb 2026

The Expanding Landscape of NLRC4 Inflammasome in Various Inflammatory and Infectious Diseases

Tandon R*, Goswami A, Nandave M, Reddy PN, Vohora D, Siwan D, Roy S and Dhalla NS
Background: The Nucleotide-binding oligomerization domain-Like Receptor family CARD domain-containing 4 (NLRC4) inflammasome is a critical component of innate immunity. As an intracellular pattern recognition receptor, N…
Vol.7, Issue 2 10.37871/jbres2274 ISSN: 2766-2276
37 Views 75 Downloads
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Open Access 28 Feb 2026

Giant Chondrolipoma of the Breast: A Rare Report of Breast within a Breast

Mishra A, Suhrid C, Pandya JS* and Laspal R
Vol.7, Issue 2 10.37871/jbres2276 ISSN: 2766-2276
27 Views 71 Downloads
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Open Access Case Report / Case Series 25 Feb 2026

Genital Schistosomiasis - Induced Infertility: A Case Report

Al-Ghoury AA*, Obaid J and Al-Quhaiti M
Bilharzias is Schistosomiasis is prevalent in tropical and subtropical countries such as Yemen. Urogenital schistosomiasis can cause infertility in both males and females. Severe schistosomiasis can cause intense granulo…
Vol.7, Issue 2 10.37871/jbres2271 ISSN: 2766-2276
29 Views 63 Downloads
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Open Access Review Article 19 Feb 2026

Bleeding and Thrombotic Complications in Patients with Premalignant Hematologic Conditions: Diagnostic and Therapeutic Challenges

Nowroozi M*
Premalignant hematology patients categorized as monoclonal B-cell lymphocytosis, clonal cytopenia of indeterminate importance, monoclonal gammopathy of unknown relevance, and clonal hematopoiesis. These disorders are cat…
Vol.7, Issue 2 10.37871/jbres2269 ISSN: 2766-2276
45 Views 63 Downloads
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Open Access Review Article 16 Dec 2025

FAM40A Deficiency Activates the Hippo Pathway to Promote Podocyte Apoptosis and Contribute to FSGS

Chen Z and Guo Z
Background: Focal Segmental Glomerulosclerosis (FSGS), a major cause of end-stage renal disease, is characterized by podocyte loss via apoptosis and cytoskeletal disruption. Although dysregulation of the Hippo-YAP pathwa…
Vol.6, Issue 12 10.37871/jbres2240 ISSN: 2766-2276
107 Views 69 Downloads
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Open Access Review Article 05 Nov 2025

The Cellular Crosstalk between the Endothelial Cells and Immune Cells in the Metastasis of NSCLC

Wang J, Huang Y, Jin Y, Liu G
Background: Bone and brain metastasis are common in the NSCLC, and tumor environment has played a vital role in the metastasis, endothelial cells are a key component of the tumor microenvironment and its role in the deve…
Vol.6, Issue 11 10.37871/jbres2217 ISSN: 2766-2276
205 Views 73 Downloads
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Open Access Review Article 19 Sep 2025

Clinical Features of AL Amyloidosis Presenting with Raccoon Eyes: A Case Report and Literature Review

Xie Yijie, Zhu Chao and Chen Zhou*
Objective: This study presents and examines the clinical profiles of 28 patients with immunoglobulin light chain (AL) Amyloidosis who exhibit the characteristic “raccoon eye” appearance. It seeks to delineate the typ…
Vol.6, Issue 9 10.37871/jbres2183 ISSN: 2766-2276
311 Views 74 Downloads 1 Citation
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Open Access Case Report 20 Jun 2025

Anastomotic Renal Sinus Haemangioma - A Case Report

Mariella Izzo, Francesco Negri, Rosario Gnazzo, Nicola Bertini, Francesco Verrengia, Simona Petrosino, Simone Cilio, Paolo Verze and Vincenzo Ciccone*
Rationale: Vascular tumours of the kidney are a heterogeneous group of lesions showing common characteristics with malignant neoplasms, making it significantly challenging the pre-operative diagnosis. Among these lesions…
Vol.6, Issue 6 10.37871/jbres2128 ISSN: 2766-2276
224 Views 80 Downloads
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Open Access Review Article 16 Jun 2025

Modulation of Inflammation in Cardiac Function after Myocardial Infarction

Behrooz G Sharifi* and Prediman K Shah
Vol.6, Issue 6 10.37871/jbres2120 ISSN: 2766-2276
521 Views 77 Downloads 1 Citation
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Open Access Editorial 30 Apr 2025

Cancer & Oncology Research: Driving Innovations for Better Outcomes

Giordana B*
Vol.6, Issue 4 10.37871/jbres2096 ISSN: 2766-2276
412 Views 87 Downloads
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Open Access Research Article 28 Apr 2025

Inflammation Markers and HCC Aggressiveness

Brian Irving Carr* and Rossella Donghia
Background: Inflammation is thought to be important in the development and progression of Hepatocellular Carcinoma (HCC), but which inflammatory indices are more useful in clinical practice is not clear.Aims: Several inf…
Vol.6, Issue 4 10.37871/jbres2093 ISSN: 2766-2276
444 Views 103 Downloads
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Open Access Observational Studies 07 Oct 2024

Shroud of Turin What Happened to Jesus Christs Human Body after Death?

Giulio Fanti*
Based on the compatibility between what can be scientifically detected on the TS (Turin Shroud) - having recognized Jesus Christ in the double body image visible there - and what is reported in the CHB (Christian Holy Bi…
Vol.5, Issue 10 10.37871/jbres2015 ISSN: 2766-2276
2,189 Views 230 Downloads
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Open Access Case Report 31 Aug 2024

Unusual Cause of the Chest Pain: Oesophageal Lipoma

Jabali Fatima A, Alganm Sara A, Alrajhi Sulaiman M, Alotaibi Tareq Z, Alghamdi Abdulaziz A and Daghistani Rayyan A*
Vol.5, Issue 8 10.37871/jbres1990 ISSN: 2766-2276
293 Views 104 Downloads
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Open Access Case Report 12 Aug 2024

Crystal Induced Colitis Mimicking Crohns Disease

Davi Viana Ramos, Eloy Vianey Carvalho de Franca, David Ramos da Silva and Alexandre de Sousa Carlos*
Crystal-induced colitis, a rare complication of sevelamer therapy in Chronic Kidney Disease (CKD) patients, presents diagnostic challenges. We report a case of a 39-year-old man with severe lower gastrointestinal bleedin…
Vol.5, Issue 8 10.37871/jbres1977 ISSN: 2766-2276
309 Views 117 Downloads
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Open Access Case Report 21 Jun 2024

Aeromonas hydrophila Septicaemia in a 6-Month-Old Infant: A Case Report

Williams Oluwatosin Adefila*, Isaac Osei, Keita Modou Lamin, Baleng Mahama Wutor, Yusuf Abdulsalam Olawale, Minteh Molfa, Ousman Barjo, Mayowa Omotosho, Rasheed Salaudeen and Grant Mackenzie
Background: Aeromonas hydrophila, a Gram-negative, motile, facultative anaerobe, is emerging as a serious pathogen. It is found in water, soil, and food, causing various infections, from mild diarrhoea to life-threatenin…
Vol.5, Issue 6 10.37871/jbres1936 ISSN: 2766-2276
388 Views 96 Downloads 1 Citation
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Open Access Commentary 14 Jun 2024

Predictive Pathologic Features of Nodal Metastasis and Tumor Recurrence in HPV-Associated Endocervical Adenocarcinoma

Yue Wang and Wenxin Zheng*
Endocervical Adenocarcinoma (EAC) is the second most prevalent malignancy of the uterine cervix, with a significant portion linked to high-risk HPV infection [1]. The incidence of EAC has risen notably, now accounting fo…
Vol.5, Issue 6 10.37871/jbres1928 ISSN: 2766-2276
360 Views 98 Downloads
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Open Access Editorial 08 Jun 2024

The Promise of Tumor Mutation Burden and Microenvironment as Biomarkers in Glioma Treatment

David J Park* and Steven D Chang
Gliomas, particularly high-grade gliomas like glioblastomas, represent some of the most formidable challenges in oncology. These brain tumors are notorious for their resistance to conventional therapies, including surger…
Vol.5, Issue 6 10.37871/jbres1923 ISSN: 2766-2276
419 Views 103 Downloads
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Open Access Original Article 26 Jan 2024

Comparative Evaluation of Microorganism Disinfection Methods for N95 Respirators

Satoshi Mitarai*, Jun Noda, Satoshi Gondaira, Ikuo Uchida and Rikio Kirisawa
Background: An excessive demand for N95 respirators occurred during the SARS-CoV-2 pandemic. Therefore, health care workers were obligated to reuse N95 respirators, which were intended to be disposable.Aim: The primary o…
Vol.5, Issue 1 10.37871/jbres1874 ISSN: 2766-2276
1,086 Views 142 Downloads
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Open Access Research Article 15 Sep 2023

Complexity, Diversity, Homogeneity and Topology Measures Re-Define Biological Tumor Aggressiveness as a Function of Intercellular Connectivity

Przemyslaw Waliszewski*
Similarity between patterns of cellular self-organization in primary tumor and in its normal counterpart underlies the concept of biological tumor aggressiveness. That subjective parameter is supposed to correlate with b…
Vol.4, Issue 9 10.37871/jbres1798 ISSN: 2766-2276
1,045 Views 120 Downloads 2 Citations
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Open Access Mini Review 31 Dec 2022

Non-Ventilatory Co-Factors of Ventilator-Induced Lung Injury

Lauren Thornton DO* and John J Marini MD
Numerous experimental studies demonstrate key aspects of mechanical ventilation which initiate or exacerbate acute lung injury, characterized by proteinaceous edema, inflammation, and hemorrhage. The great majority of th…
Vol.3, Issue 12 10.37871/jbres1639 ISSN: 2766-2276
953 Views 89 Downloads
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Open Access Review Article 30 Nov 2021

Alzheimers Disease-Like Neuropathology Following Exposure to Ambient Noise

Mojtaba Ehsanifar*, Zeinab Montazeri and Mehravar Rafati
Many factors play a role in the risk of dementia, including the environment. Widespread and significant worldwide exposure to noise, the severity of related health consequences, and the limited tools available to the pub…
Vol.2, Issue 11 10.37871/jbres1364 ISSN: 2766-2276
1,468 Views 71 Downloads 8 Citations
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Open Access Clinical Image 09 Sep 2021

Reflection on the benignity or pathology of the presence of U waves in the electrocardiogram

Iribar Dieguez IK, Lucas Cabornero J and Lopetegui Cano M
We present the electrocardiogram (Figure 1) of a 14-year-old man in which, without related pathology, and incidentally in the context of a consultation for another reason, a U wave was detected in precordial leads V3 and…
Vol.2, Issue 9 10.37871/jbres1309 ISSN: 2766-2276
2,386 Views 70 Downloads
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