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Research Articles
37 articles
Open Access
12 Jun 2026
Long Term Application of Artemether Improved Language and Cognitive Deficit of Chronic Ischemic Stroke Patient: A Case Report
Stroke is the first cause of death and disability among adults with limited treatment approaches. According to the Wolfe’s survey, the five-year recurrence risk of ischemic stroke ranges from 15% to 40%. Given the rapidl…
55 Views 45 Downloads
Open Access
Research Article 14 Apr 2026
The Neurological Renaissance: Elucidating the Complex Relationship between Syphilis and Neurodegenerative Disorders in the Contemporary Era
The global resurgence of syphilis has coincided with increasing evidence of complex interactions between Treponema pallidum infection and neurological disorders, extending beyond classical neurosyphilis manifestations. T…
26 Views 52 Downloads
Open Access
Review Article 18 Feb 2026
From Brain Evidence to Neurorights: Rethinking Criminal Responsibility in the Age of Neurotechnology
The article, which raises never-before-bioethical and legal questions, is a consideration of the manner in which rapid advances in neurotechnology are reshaping criminal law. Neurotechnology is changing how we think abou…
49 Views 70 Downloads
Open Access
Observational Studies 05 Dec 2025
Integrating Serum Biomarkers and Genetic Polymorphisms for Alzheimer’s disease Risk Screening
Objective: Analyze the differences in the detection results of Alzheimer’s Disease (AD) serum biomarkers and the expression of APOE and SLCO1B1 genotypes, then construct an AD diagnostic model integrating serum biomark…
105 Views 75 Downloads
Open Access
Review Article 18 Oct 2025
Neurotoxicants on the Menu: Mapping the Link between Food Contaminants and Autism in African Children - A Scoping Review
Background: Autism Spectrum Disorder (ASD) is a growing neurodevelopmental concern in Africa, with environmental risk factors such as neurotoxic food contaminants believed to play a role in its prevalence among children.…
319 Views 77 Downloads
Open Access
Review Article 18 Oct 2025
A Comprehensive Review of Computational Modeling in Tumor and Brain Disorder with a Focus on Ablation Therapies
This review paper provides a comprehensive overview of computational modeling approaches applied to the study of tumors and brain disorders, with a particular focus on ablation therapies. We delve into the fundamental pr…
277 Views 73 Downloads
Open Access
Case Report 27 Aug 2025
A Typical Neuroleptic Malignant Syndrome Presenting with Hyponatremia
Neuroleptic Malignant Syndrome (NMS) is a rare but potentially fatal neurological complication of medications affecting the central dopaminergic system, especially antipsychotic agents. According to one theory, decreased…
170 Views 88 Downloads
Open Access
Review Article 18 Aug 2025
AWAKEN Regenerative Intelligence - How Consciousness Evolution Guides the $115 Trillion Intergenerational Wealth Transfer toward Life-Serving AI-Governance
"The next “moonshot’ isn’t technological-it’s the leap from 5% to 100% human capacity of awakening “consciousness†for intergenerational well-beingâ€.We're living through a paradox of staggering potential an…
377 Views 82 Downloads
Open Access
Review Article 31 Jul 2025
Role of Cyclooxygenase-2 Inhibitors in Animal Models of Epilepsy: A Systematic Review
Background: The presence of recurrent seizures characterizes epilepsy, which is defined as a chronic disorder of the nervous system. It has recently been suggested that COX-2 inhibitors may offer protective neurotherapeu…
531 Views 105 Downloads
Open Access
Case Report 16 Jul 2025
Case Presentation Corticosteroids as the treatment of Left Hypoglossal Nerve Paralysis in a 35-Year-Old Man Following a Jiu Jitsu Training Maneuver
This case report describes a rare instance of isolated left hypoglossal nerve (cranial nerve XII) paralysis in a 35-year-old male following a jiu jitsu training session. The patient presented with acute-onset dysarthria …
707 Views 75 Downloads
Open Access
Review Article 16 Jun 2025
Analysis and Control of Alzheimers Disease Models
Millions of people are affected by Alzheimer's disease, which is a progressive neurodegenerative disorder. It is important to understand the progression dynamics of this disease to be able to minimize the damage that is …
257 Views 75 Downloads
Open Access
Review Article 27 Mar 2025
Pregnancy and Menieres Disease
Pregnancy is well known to cause further progression of the clinical symptoms of Ménière’s disease. However, mild low-tone hearing loss and ear fullness, similar to the hearing impairment of Ménière’s disease, is…
2,594 Views 120 Downloads
Open Access
Review Article 19 Mar 2025
Stewarding Regenerative Experience (RX): AI-Quantum for Humanity in Cognitive, Health and Well-being
As Artificial Intelligence (AI), quantum intelligence, and deep technologies advance rapidly, human cognitive flexibility, emotional resilience, and adaptability are experiencing a significant decline. AI excels in optim…
1,847 Views 93 Downloads
Open Access
Mini Review 15 Mar 2025
Can Ketamine Treat Schizophrenia?
NMDAR antagonists, such as memantine and ketamine, have demonstrated efficacy in treating neurodegenerative diseases and major depression. Our recent findings reveal that these antagonists significantly enhance 20S prote…
2,113 Views 102 Downloads
Open Access
Case Series 09 Nov 2024
Impact of Deep Brain Stimulation on Addictive Behaviors A Case Series of Parkinsonians Patients
Deep brain stimulation of the Subthalamic Nucleus (STN-DBS) is a recognized treatment in Parkinson’s disease (PD), but knowledge is still limited regarding its possible impact on patients with Behavioral Addiction (BA)…
1,735 Views 117 Downloads
Open Access
Case Report 30 Sep 2024
Stroke as the First Sign of Heart Tumor What the Neurologist should know about Heart
Primary heart cancers are rare, but cancer metastases occur much more often, which is why they are diagnosed mainly in non-oncology departments. Approximately 85% of heart cancers are benign, with myxoma predominating [1…
190 Views 119 Downloads
Open Access
Research Article 11 Sep 2024
Reduced Number of Oligodendrocytes in the Cingulum in Schizophrenia: A Design-Based Stereology Study
Schizophrenia is a severe mental disorder with a neurodevelopmental origin whose pathophysiological processes are poorly understood. Magnetic resonance imaging studies have shown structural alterations, such as volume lo…
431 Views 108 Downloads 1 Citation
Open Access
Commentary 11 Sep 2024
Limitations of Current Treatment of Alzheimer’s Disease and Proposed Plan to Improve it
878 Views 119 Downloads
Open Access
Editorial 08 Jun 2024
The Promise of Tumor Mutation Burden and Microenvironment as Biomarkers in Glioma Treatment
Gliomas, particularly high-grade gliomas like glioblastomas, represent some of the most formidable challenges in oncology. These brain tumors are notorious for their resistance to conventional therapies, including surger…
419 Views 103 Downloads
Open Access
Case Report 22 May 2023
Sympathetic Sudomotor Ganglionopathy Following Envenomation from a Northern Australia Jellyfish Irukandji Syndrome
The oceans of northern Australia coastal beaches harbor numerous venomous jellyfish. Several species cause Irukandji Syndrome, a severe disorder (developing within an hour after a sting) consisting painful muscle cramps,…
1,019 Views 89 Downloads
Open Access
Case Report 04 May 2023
Electroconvulsive Therapy for the Anti-NMDA Receptor Encephalitis: A Case Report
Anti-NMDA encephalitis is a rare autoimmune disorder that affects the central nervous system. We report a case of a 22-year-old male patient with a history of prodromal flu-like symptoms followed by brief aggression epis…
860 Views 96 Downloads
Open Access
Case Series 27 Apr 2023
Heads or Tails: Incomplete Penetrance and Variable Expressivity at 15q11.2 Microdeletion (BP1-BP2)
Neurodevelopmental disorders are a group of pathologies with increased frequency in pediatric practice. During the last decade, genetic studies such as CGH arrays have aided in the search for genetic gains or losses that…
804 Views 89 Downloads
Open Access
Perspective 26 Dec 2022
Can Endomicroscopic Tissue Characterization be Combined with Deep Machine Learning to Support Neurosurgery?
Confocal Laser Endomicroscopy (CLE) is a new technique that is able to show cell structures during surgery. The interpretation of CLE data for tissue characterisation during brain tumour resection is challenging even amo…
468 Views 93 Downloads
Open Access
Mini Review 29 Apr 2022
Post-COVID Syndrome During the COVID-19 Pandemic and the Impact of COVID-19 on the Brain
The review provides information on the classification, mechanisms of development of infection and multiple organ damage, as well as clinical manifestations of post-COVID syndrome (Post-СOVID Conditions, Long COVID, Post…
4,364 Views 94 Downloads
Open Access
Mini Review 28 Feb 2022
Neuroprotective Effects of Thiazolidine-4-Carboxylic Acid Derivatives on Memory Impairment and Neurodegeneration
Some studies have shown numerous biological activities of Thiazolidine derivatives, including neuroprotection. The production of inflammatory markers and Reactive Oxygen Species (ROS) plays a major role in nerve damage t…
2,297 Views 94 Downloads
Open Access
Review Article 26 Feb 2022
CNS Demyelination Diseases Following Exposure to Urban Air Pollution
Epidemiology findings show that exposure to urban air pollutants as a source of oxidative stress and neuroinflammation is associated with the Central Nervous System (CNS) demyelinating diseases, such as Multiple Sclerosi…
2,541 Views 90 Downloads 2 Citations
Open Access
Review Article 31 Jan 2022
Parkinsons Disease-Like Neuropathology and Phenotype Following Induction of Oxidative Stress and Inflammation in the Brain
Parkinson’s Disease (PD) is a neurodegenerative disorder characterized by motor deficits caused by the loss of dopaminergic neurons in the Substantia Nigra (SN) and Ventral Tegmental Area (VTA). However, clinical data …
2,108 Views 96 Downloads 1 Citation
Open Access
Opinion 04 Jan 2022
Assessment of Psychiatric Issues in Post-concussion Syndrome
The term "Post-Concussion Syndrome" (PCS) refers to a group of non-specific symptoms that occur after a concussion or Mild Traumatic Brain Injury (MTBI) and last longer than expected. Headaches, weariness, vertigo/dizzin…
1,620 Views 107 Downloads
Open Access
Case Report 30 Oct 2021
Fovilles Syndrome a Case to Remember Case Report
The Foville’s Syndrome is a rare clinical feature of stroke or brain hemorrhage. This is very rare brain stem syndrome and only few cases have been reported worldwide. A case of Foville's syndrome secondary to infarcti…
3,719 Views 75 Downloads
Open Access
Letter to Editor 29 Sep 2021
Artificial Intelligence in Cranial Surgeries
Artificial Intelligence (AI) is a broad phrase that refers to any machine’s activity that would otherwise need human intellect.Recent technological advancements have closed the gap between human and machines, allowing …
1,243 Views 79 Downloads 1 Citation
Open Access
Research Article 27 Jul 2021
Research Progress in the Repair of Peripheral Nerve Injury with Adipose-Derived Stem Cell Exosomes
The repair of peripheral nerve injury has always been a difficult clinical problem. Although a variety of treatment methods are available in clinical practice, their efficacy is limited. In recent years, the components c…
24 Views 122 Downloads
Open Access
Research Article 15 Jul 2021
Potential Clinical Benefits of Combination of Black Seed, Licorice and Turmeric Supplements within the Treatment Regimens of Bells Palsy
Bell’s palsy can be considered as one of the most resistant and idiopathic neuromuscular facial diseases. It has not any specific effective treatments up to date in 2021. The aim of this article is to introduce this ne…
7,674 Views 151 Downloads
Open Access
Letter to Editor 27 May 2021
Neurological Manifestations of COVID-19 Patients and Management
SARS-CoV-2 was first observed in Wuhan, China, and quickly spread throughout the world, proclaimed as a pandemic by WHO.Most reported cases have respiratory symptoms, but many cases are seen with neurological signs as in…
4,582 Views 110 Downloads
Open Access
Case Study 25 Mar 2021
Occurrence of Epileptic Complications in Patients with Cerebrovascular Disease in Charge to the Home Care Center: A Clinical Experience
Most studies in literature about the occurrence of the so-called vascular epilepsy suggest that this complication is an episodic and relatively rare event mostly due to clinical conditions related to haemorrhagic ictus w…
1,179 Views 88 Downloads
Open Access
Case Study 06 Mar 2021
Recurrent Pituitary Tumor and Use of Minidoppler to Avoid Carotid Artery Injury
Study objective: To learn how to avoid injury to the carotid artery during recurrent pituitary surgery.Design: Through transsphenoidal endonasal approach the steps of surgery with avoidance of complications were describe…
1,901 Views 236 Downloads
Open Access
Review Article 23 Aug 2020
Ecological Dynamics: An Inspiration for Triggering Epilepsy
Epilepsy is a rigorous transmission of electrical impulses across neurons of the brain and reported more prevalent in lower-income countries. A systematic literature review has been performed to implicate the impact of e…
5,260 Views 289 Downloads
Open Access
Case Report 27 May 2020
Malignant Cerebral Ischemic Stroke Associated with COVID-19 Infection
Introduction: Coronavirus Disease 2019 (COVID-19) originating from Wuhan, China, is spreading around the world. Apart from respiratory, cardiac and vascular complications, acute neurological symptoms and acute cerebrovas…
2,246 Views 911 Downloads
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