Special Issue
Data-Driven Discovery: Biostatistics, Biometrics & Computational Science
Guest Editor: Yingjun Zhao — Department of Intelligent Manufacturing Engineering, Xinjiang University, China
Submission
Covid-19 Research
Safety Profile of COVID-19 Vaccines: Retrospective Analysis of Short, Medium, and Long-Term Side Effects: The Military Hospital Experience – Read more Evaluating the Efficacy of Different SARS-Cov-2 Drug Targets Using the Topo-Geometrical Superposition Algorithm, Molecular Docking and Chemical Reactivity Frameworks – Read more Preventing COVID-19 Infection by Complementary Medicine and Oral Health – Read more Analysis of Body Temperature in Patients with Trauma Visiting a Local Emergency Medical Center during the SARS-CoV-2 Outbreak – Read more N95 Respirator Fit Testing Experience during the Pandemic at a Singapore Tertiary Health Institution: Streamlining Workflow and Improving Respirator Fit Rate – Read more COVID-19 is an Amplifier of Social Inequalities Structural Violence against Students with Special Learning Needs and Low Socio-Economic Status – Read more Interaction between Chronic Influenza and COVID-19: Novel Aspects of Immune System Combat – Read more Daily Life, Fear of COVID-19 and Social Support in the Older Adults in Home Isolation: A Cross-Sectional Study – Read more The Impact of COVID-19 Pandemic on Cardiovascular Diseases in Brazil – Read more Diversity of Non-Influenza Respiratory Viruses Associated with Influenza-Like Illness during 2009 pre and pandemic periods in Sao Paulo, Brazil, a Historical Overview – Read more Cardiovascular Complications of SARS-CoV-2 (COVID-19) in Adults – Read more Impact of COVID-19 Pandemic on the Development of Childrens Executive Functions Implications for School-Based Interventions – Read more The Impact of the COVID-19 Pandemic on Youth Education – Read more Association between Dietary Habits, Lifestyle and Migraine Attacks During Social Isolation in the COVID-19 Pandemic: A Systematic Review of Observational Studies – Read more The Brazilian Increase in Cases of Lung Cancer and COVID-19, Can They be related? – Read more The Possible Therapeutic Application of CO on COVID-19 – Read more Planetary View of COVID Impact vs. IQ & PISA Rank as National Level of Intelligence – Read more Electrophysiological Study in a Patient with Visual Deficit after Severe Coronavirus 2 Pneumonia – Read more A Presentation of Analyses of COVID-19 Vaccine Samples, Blood Samples, Urine Samples, Foot Bath Samples, Sitz Bath Samples, and Skin-Extract Samples – Read more Is Anosmia-Ageusia in COVID-19 Patients Associated with Neuro-Philic Virus Mutant and Mild Respiratory Involvement? – Read more

Therapeutics

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25 Articles Open Access Medicine Group Submit to this Topic
25
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81,432
Total Views
3,640
Downloads
56
Citations
28
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TherapeuticsThese topics are filtered from our journals helping to discover the community within the widespread of multi-disciplinary Have a look at this page once and make your article more discoverable in our esteemed journal to ensuring readers find your article through search engines such as Google.

Research Articles

25 articles
Open Access 31 Mar 2026

Combined Dopaminergic Drugs to Treat Pyoderma Gangrenosum

Jerome H Check* and Diane L Check
Monoclonal antibody therapy directed against certain pathways leading to the eventual cellular immune reaction to an irritating agent has been a mainstay of therapy for many pathological conditions considered autoimmune …
Vol.7, Issue 3 10.37871/jbres2286 ISSN: 2766-2276
39 Views 51 Downloads
Open Access Research Article 09 Mar 2026

Formulation Development, Analytical Validation and In vitro Assessment of a Generic Lymecycline 408 mg Hard Capsule

Ali Raza, Noor Zulfi qar*, Yameen HM, Fatima A, Rizwan M, Mahmood I, Ain QU and Imran M
This study documents the stepwise development and evaluation of a generic Lymecycline 408 mg hard gelatin capsule manufactured locally in Pakistan. The formulation process began with the selection of suitable pharmacopei…
Vol.7, Issue 3 10.37871/jbres2278 ISSN: 2766-2276
32 Views 62 Downloads
Open Access Letter 20 Jan 2026

Poly-De-Prescribing to Treat the Iatrogenic Epidemic of Polypharmacy - A Major Public Health Challenge

Garfinkel D
Vol.7, Issue 1 10.37871/jbres2257 ISSN: 2766-2276
49 Views 69 Downloads
Open Access Research Article 08 Nov 2025

Refluward® HA: Efficacy and Safety in Patients with Gastro-Esophageal Diseases

Mancheno Ferreras R, Di Maio U, Cerciello A
The physiological activity of stomach and esophagus is often impaired by the onset of various diseases such as Gastroesophageal Reflux Disease (GERD), esophagitis, hiatal hernia, tertiary esophageal waves, Barrett’s es…
Vol.6, Issue 11 10.37871/jbres2218 ISSN: 2766-2276
140 Views 77 Downloads
Open Access Perspective 23 Oct 2025

Quercetin Analogs as Cancer Chemopreventive Agents: A New Perspective

Aliabadi A, Mahboubi RM, Bayat L, Hakimimofrad R, Ghobadi K, Omidifard N, Chaman A, Bayanati M and Zarghi A*
Quercetin is a flavonoid-type chemical molecule found in many people's daily diets. Previous research has shown that quercetin offers a range of benefits, including anti-inflammatory, antioxidant, and cancer-prevention p…
Vol.6, Issue 10 10.37871/jbres2207 ISSN: 2766-2276
817 Views 80 Downloads
Open Access Review Article 08 Oct 2025

The Beneficial Role of Exercise and Whole-Food Plant-Based Diet in Coronary Artery Disease Prevention and Management

Dasaad Mulijono*
Coronary Artery Disease (CAD) remains a critical global health issue, substantially contributing to morbidity and mortality worldwide. The strategic combination of Regular Physical Exercise (RPE) and a Whole-Food Plant-B…
Vol.6, Issue 10 10.37871/jbres2196 ISSN: 2766-2276
1,708 Views 91 Downloads
Open Access Clinical Trials 30 Aug 2025

Tocilizumab Therapy in Giant Cell Arteritis: Insights from Clinical Experience

Ricardo Blanco* and Javier Loricera
Vol.6, Issue 8 10.37871/jbres2174 ISSN: 2766-2276
209 Views 67 Downloads
Open Access Research Article 27 Aug 2025

NUVATUL-MZ Ointment for the Treatment of Ganglion Cyst

Vama Bhavsar, Tulsi Bhatia, Nupur Shah, Zalak Dave, Mihir Y Parmar* and Prachi Pandey
The most frequent soft tissue masses in the hand and wrist are ganglion cysts, which are the reason for a large portion of orthopaedic and hand surgery clinic appointments. Although these cysts are usually benign, they c…
Vol.6, Issue 8 10.37871/jbres2171 ISSN: 2766-2276
1,005 Views 92 Downloads
Open Access Perspective 11 Aug 2025

Harnessing Nutrition to Prevent Coronary Recoil in Drug-Coated Balloon Angioplasty: Insights from Bethsaida Hospital

Dasaad Mulijono*
The success of Drug-Coated Balloon (DCB) angioplasty hinges critically on effectively preventing coronary artery recoil, an acute elastic response that threatens procedural efficacy and long-term vessel patency. While te…
Vol.6, Issue 8 10.37871/jbres2158 ISSN: 2766-2276
544 Views 79 Downloads
Open Access Case Report 16 Jul 2025

Case Presentation Corticosteroids as the treatment of Left Hypoglossal Nerve Paralysis in a 35-Year-Old Man Following a Jiu Jitsu Training Maneuver

Zacharias Kalentakis*
This case report describes a rare instance of isolated left hypoglossal nerve (cranial nerve XII) paralysis in a 35-year-old male following a jiu jitsu training session. The patient presented with acute-onset dysarthria …
Vol.6, Issue 7 10.37871/jbres2142 ISSN: 2766-2276
707 Views 75 Downloads
Open Access Opinion 09 Jul 2025

Cracks in the Evidence: Why Studies from COURAGE to ISCHEMIA Failed to Show Benefit of Stenting PCI

Dasaad Mulijono*
Percutaneous Coronary Intervention (PCI) with stenting remains widely utilized for managing Chronic Coronary Syndrome (CCS). However, landmark clinical trials such as COURAGE and ISCHEMIA have repeatedly shown no signifi…
Vol.6, Issue 7 10.37871/jbres2140 ISSN: 2766-2276
633 Views 74 Downloads
Open Access Original Article 30 Jun 2025

The Abiwaijiwuli-Mufasili Attenuates Cartilage Damage and Ameliorates Osteoarthritis In vivo and In vitro By Regulating Serpina3-Mediated Wnt/b-Catenin Pathway

Qin Ma, Xinyi Liu, Xiaomin Wang, Rui Liu, Jingjing Li, Jialin Wu, Zhe Xu, Peipei Wang and Wei Chen*
Introduction: Aibiwajiwuli-Mufasili (ABYJ), an ancient classic formula of Uyghur medicine, is used to treat osteoarthritis (OA) in clinical practice in China, yet the underlying mechanism remains obscure. We aimed to pro…
Vol.6, Issue 6 10.37871/jbres2132 ISSN: 2766-2276
320 Views 86 Downloads
Open Access Perspective 30 Jun 2025

Transforming Cardiac Care through Plant-Based Diets: A Breakthrough Experience from Bethsaida Hospital, Indonesia

Ali Usman*
Seven years ago, at Bethsaida Hospital in Indonesia, Professor Dasaad Mulijono pioneered the integration of a Plant-Based Diet (PBD) into routine cardiac caresa paradigm shift that has dramatically improved outcomes for …
Vol.6, Issue 6 10.37871/jbres2135 ISSN: 2766-2276
609 Views 85 Downloads
Open Access Review Article 24 Apr 2025

Healing with Food or Managing with Injection? A New Era in Chronic Disease Care

Dasaad Mulijono*
The global burden of chronic diseases, particularly obesity, diabetes, and cardiovascular diseases, continues to rise. While pharmacological interventions, such as Semaglutide, provide short-term benefits in weight manag…
Vol.6, Issue 4 10.37871/jbres2092 ISSN: 2766-2276
494 Views 102 Downloads 1 Citation
Open Access Review Article 15 Feb 2024

Drug Design Strategies, Modes of Action, Synthesis and Industrial Challenges Behind Trifluoromethylated New Chemical Entities

Leitao EPT* and Sobral LMS
Medicinal plants have been an inspiration source for developing new chemical entities, providing diverse chemical structures and modes of action for medicinal chemistry strategies. Modern medicinal chemistry approaches p…
Vol.5, Issue 2 10.37871/jbres1883 ISSN: 2766-2276
30,342 Views 120 Downloads 5 Citations
Open Access Short Communication 12 Mar 2023

The Possible Therapeutic Application of CO on COVID-19

Zhang Rui-Gang*
An outbreak of pneumonia caused by a novel Coronavirus (2019-nCoV) is ongoing in China [1]. The disease caused by 2019-nCoV was recently named as COVID-19 by WHO. Although the case-fatality rate of COVID-19 (about 2.3% u…
Vol.4, Issue 3 10.37871/jbres1687 ISSN: 2766-2276
2,463 Views 49 Downloads
Open Access Review Article 19 Jan 2023

ET-traps: A Potential Therapeutic for Use in Human Complications of the Heart and Kidneys

Arjun Jain and Ira Jain*
Endothelin-1 (ET-1) is a potent bioactive mediator that induces vasoconstriction and promotes vascular remodeling. Previous studies indicate that ET-1 plays an important role in the pathophysiology of humans. This includ…
Vol.4, Issue 1 10.37871/jbres1646 ISSN: 2766-2276
1,545 Views 94 Downloads
Open Access Review Article 24 Dec 2022

Characteristics of the Gut Microbiota in Rheumatic Diseases and Promising Therapeutic Strategies

Shangui Zhang and Xuyan Yang*
Over the past twenty years, the link between gut microbes and human autoimmune diseases has attracted extensive attention. Available studies have shown that alterations in gut microbiota are closely related to the develo…
Vol.3, Issue 12 10.37871/jbres1627 ISSN: 2766-2276
2,108 Views 86 Downloads
Open Access Opinion 24 Dec 2022

Economic Evaluation: Advantages of Implementing Drug Track and Trace beyond Health Benefits

Fernanda Maciel Rebelo*, Vidal Augusto Zapparoli Castro Melo, Alinne Lopomo Beteto and Eduardo Mario Dias
Traceability is a valuable strategy to prevent the administration of counterfeit and substandard medicines, but despite being an efficient risk management strategy, it has high implementation and operational costs. An ec…
Vol.3, Issue 12 10.37871/jbres1628 ISSN: 2766-2276
666 Views 78 Downloads 1 Citation
Open Access Opinion 21 May 2022

The Worldwide Herbal Market: Trends and Opportunities

Sechaba Bareetseng*
For many centuries, plant species have been used by local and indigenous communities as part of their culture and traditions for the preparations of medicines to treat, both human and animal diseases. Local and Indigenou…
Vol.3, Issue 5 10.37871/jbres1482 ISSN: 2766-2276
11,184 Views 97 Downloads 40 Citations
Open Access Review Article 20 Nov 2021

Emerging Therapeutic Role of CDK Inhibitors in Targeting Cancer Stem Cells

Sadia Perveen, Hanfa Ashfaq#, Mehak Shahid, Ambreen Kanwal and Asima Tayyeb*
Within a tumor, Cancer Stem Cells (CSCs) exists and own similar characteristics of a normal stem cell thus contributing towards aggressiveness of cancer by playing crucial role in tumor recurrence and metastasis capabili…
Vol.2, Issue 11 10.37871/jbres1355 ISSN: 2766-2276
1,892 Views 68 Downloads 2 Citations
Open Access Review Article 22 Dec 2020

Pharmacodynamics of Remdesivir: How to Improve for COVID-19 Treatment

Ashok Chakraborty* and Anil Diwan
Potential clinical benefit in SARS-CoV-2 with remdesivir have been noticed. Recently, FDA has granted the use of remdesivir for COVID-therapy. However, the efficacy of remdesivir alone or with combination of other antivi…
Vol.1, Issue 8 10.37871/jbres1175 ISSN: 2766-2276
8,640 Views 486 Downloads 2 Citations
Open Access Review Article 23 Nov 2020

The Kinetics of Glucose Transport in Human Red Blood Cells Depend on Their Metabolic State

Gunter Fred Fuhrmann*
This article about freshly drawn human red blood cells offers new insights in regulation of glucose transport. Transport of glucose in Glut1 red blood cells is highly asymmetric and depend on metabolic energy, most proba…
Vol.1, Issue 7 10.37871/jbres1164 ISSN: 2766-2276
6,335 Views 591 Downloads 1 Citation
Open Access Original Article 31 Oct 2020

Repurposing Potential of Diminazene Aceturate as an Inhibitor of the E. coli DNA Gyrase B

Varsha Dwivedi, Archana Ayyagari, Rakhi Chandran, Prerna Diwan, Sanjay Gupta and Vandana Gupta*
Drug-resistant Escherichia coli (E. coli) has overburdened the healthcare facilities in recent years and is getting hard to combat, mandating search for novel therapeutics with a broad antibacterial spectrum and high che…
Vol.1, Issue 6 10.37871/jbres1153 ISSN: 2766-2276
3,612 Views 384 Downloads 1 Citation
Open Access Research Article 15 Sep 2020

Ginger (Zingiber officinale) and its Bioactive Components with Protective and Therapeutic Potential against Cancer

Meeneri Vilas Bobde, Saroj Yadav and Sibi G*
Ginger can be an important complementary medicine for prevention and treatment of different types of cancers, owing to its natural origin, safety, and low cost relative to synthetic cancer drugs. Ginger contains volatile…
Vol.1, Issue 5 10.37871/jbres1133 ISSN: 2766-2276
5,339 Views 497 Downloads 3 Citations

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