Special Issue
Data-Driven Discovery: Biostatistics, Biometrics & Computational Science
Guest Editor: Yingjun Zhao — Department of Intelligent Manufacturing Engineering, Xinjiang University, China
Submission
Covid-19 Research
Safety Profile of COVID-19 Vaccines: Retrospective Analysis of Short, Medium, and Long-Term Side Effects: The Military Hospital Experience – Read more Evaluating the Efficacy of Different SARS-Cov-2 Drug Targets Using the Topo-Geometrical Superposition Algorithm, Molecular Docking and Chemical Reactivity Frameworks – Read more Preventing COVID-19 Infection by Complementary Medicine and Oral Health – Read more Analysis of Body Temperature in Patients with Trauma Visiting a Local Emergency Medical Center during the SARS-CoV-2 Outbreak – Read more N95 Respirator Fit Testing Experience during the Pandemic at a Singapore Tertiary Health Institution: Streamlining Workflow and Improving Respirator Fit Rate – Read more COVID-19 is an Amplifier of Social Inequalities Structural Violence against Students with Special Learning Needs and Low Socio-Economic Status – Read more Interaction between Chronic Influenza and COVID-19: Novel Aspects of Immune System Combat – Read more Daily Life, Fear of COVID-19 and Social Support in the Older Adults in Home Isolation: A Cross-Sectional Study – Read more The Impact of COVID-19 Pandemic on Cardiovascular Diseases in Brazil – Read more Diversity of Non-Influenza Respiratory Viruses Associated with Influenza-Like Illness during 2009 pre and pandemic periods in Sao Paulo, Brazil, a Historical Overview – Read more Cardiovascular Complications of SARS-CoV-2 (COVID-19) in Adults – Read more Impact of COVID-19 Pandemic on the Development of Childrens Executive Functions Implications for School-Based Interventions – Read more The Impact of the COVID-19 Pandemic on Youth Education – Read more Association between Dietary Habits, Lifestyle and Migraine Attacks During Social Isolation in the COVID-19 Pandemic: A Systematic Review of Observational Studies – Read more The Brazilian Increase in Cases of Lung Cancer and COVID-19, Can They be related? – Read more The Possible Therapeutic Application of CO on COVID-19 – Read more Planetary View of COVID Impact vs. IQ & PISA Rank as National Level of Intelligence – Read more Electrophysiological Study in a Patient with Visual Deficit after Severe Coronavirus 2 Pneumonia – Read more A Presentation of Analyses of COVID-19 Vaccine Samples, Blood Samples, Urine Samples, Foot Bath Samples, Sitz Bath Samples, and Skin-Extract Samples – Read more Is Anosmia-Ageusia in COVID-19 Patients Associated with Neuro-Philic Virus Mutant and Mild Respiratory Involvement? – Read more

Immunology

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29 Articles Open Access Medicine Group Submit to this Topic
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31
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ImmunologyThese topics are filtered from our journals helping to discover the community within the widespread of multi-disciplinary Have a look at this page once and make your article more discoverable in our esteemed journal to ensuring readers find your article through search engines such as Google.

Research Articles

29 articles
Open Access Review Article 28 Jan 2026

Systemic Lupus Erythematosus: Clinical, Diagnostic, and Therapeutic Perspectives

Bergamaschi MM
Background: Systemic Lupus Erythematosus is a chronic autoimmune disease with systemic involvement, predominantly affecting women of reproductive age. Its development is related to genetic, hormonal, and environmental fa…
Vol.7, Issue 1 10.37871/jbres2261 ISSN: 2766-2276
47 Views 97 Downloads
Open Access Review Article 08 Nov 2025

Exploring the Tumor Microenvironment: Macrophages and PD-1 Checkpoint Inhibitors

Liu X, Lu Y, Wei J, Liu H, Huang J, Ding Y
This review provides an in-depth examination of the tumor microenvironment, macrophages, and PD-1 checkpoint inhibitors. It delves into the fundamental aspects of the tumor microenvironment and macrophages, discussing th…
Vol.6, Issue 11 10.37871/jbres2219 ISSN: 2766-2276
461 Views 75 Downloads
Open Access Review Article 05 Nov 2025

The Cellular Crosstalk between the Endothelial Cells and Immune Cells in the Metastasis of NSCLC

Wang J, Huang Y, Jin Y, Liu G
Background: Bone and brain metastasis are common in the NSCLC, and tumor environment has played a vital role in the metastasis, endothelial cells are a key component of the tumor microenvironment and its role in the deve…
Vol.6, Issue 11 10.37871/jbres2217 ISSN: 2766-2276
205 Views 73 Downloads
Open Access Original Article 23 Jun 2025

Age and Disease activity related Biomarkers in Takayasuarteritis: Comparison with Giant Cell Arteritis

Andrea DG, Lisa C, Jennifer LC, Harald B and Peter MV*
Background and objective: Measuring Takayasu (TAK) disease activity remains a difficult task. The aims of this study were to identify biomarkers reflecting disease activity in TAK, to analyze the effects of treatment, to…
Vol.6, Issue 6 10.37871/jbres2130 ISSN: 2766-2276
357 Views 82 Downloads
Open Access Research Article 28 Mar 2025

Potential Use of Immunological Indices as Predictors of Bacterial Infections Following Cardiopulmonary Bypass Surgery in Elderly Patients

Piotr Sindera, Barbara Zawidlak-Wegrzynska* and Ewa Kucewicz-Czech
Cardiac surgery with Cardiopulmonary Bypass (CPB) induces postoperative immunological responses in patients. We aimed to determine changes in various immunological parameters in patients during and after cardiac surgery …
Vol.6, Issue 3 10.37871/jbres2084 ISSN: 2766-2276
271 Views 140 Downloads 1 Citation
Open Access Short Communication 25 Nov 2024

Potato Derived Exosome Nanoparticles as Anti Inflammation Agents

Yeji Lee, Da-Young Jeong and Sanghwa Yang*
The screening of exosomes from various sources reveals that potato-derived exosomes exhibit the most significant anti-inflammatory activity, as demonstrated by RT-PCR analyses of Tumor Necrosis Factor expression in exoso…
Vol.5, Issue 11 10.37871/jbres2039 ISSN: 2766-2276
713 Views 127 Downloads 2 Citations
Open Access Review Article 10 Nov 2024

A Comprehensive Review of IgG4 Related Disease Unraveling the Role of B and T Lymphocytes in the Pathogenesis of the Disease

Gaia Mancuso*
IgG4-RD is a chronic fibro inflammatory disease characterized by a significant elevation of serum IgG4 concentration and marked infiltration of IgG4-positive plasma cells in the affected organs. A dense lymphoplasmacytic…
Vol.5, Issue 11 10.37871/jbres2032 ISSN: 2766-2276
6,693 Views 119 Downloads
Open Access Research Article 27 Sep 2024

Populations of Triple Negative and Hormone Receptor Positive HER2 Negative Breast Tumors Share Immune Gene Profiles

Frank Schmitz, Wilbert B Copeland, Justine Dell Aringa, Kathryn Newhall, Mary L Disis, and Sasha E Stanton*
Background: Immune therapy has revolutionized the treatment of certain cancers including melanoma and lung cancer. Breast cancer has fewer tumors with high immune infiltrate and Immune Checkpoint Inhibitor (ICI) therapy…
Vol.5, Issue 9 10.37871/jbres2008 ISSN: 2766-2276
229 Views 116 Downloads
Open Access Case Report 24 Jul 2024

Postural Orthostatic Tachycardia Syndrome (POTS) of Autoimmune Origin - Case and Review

Zora Lazurova*, Peter Mitro, Ivica Lazurova, Monika Lukacova, Harald Heidecke, Jan Lepej, Igor Marin and Yehuda Shoenfeld
Introduction: Postural Orthostatic Tachycardia Syndrome (POTS) belongs to a group of orthostatic intolerance syndromes. It is defined by the increase in heart rate ≥30 bpm or heart rate higher than 120/min during first…
Vol.5, Issue 7 10.37871/jbres1964 ISSN: 2766-2276
3,072 Views 116 Downloads 2 Citations
Open Access Editorial 08 Jun 2024

The Promise of Tumor Mutation Burden and Microenvironment as Biomarkers in Glioma Treatment

David J Park* and Steven D Chang
Gliomas, particularly high-grade gliomas like glioblastomas, represent some of the most formidable challenges in oncology. These brain tumors are notorious for their resistance to conventional therapies, including surger…
Vol.5, Issue 6 10.37871/jbres1923 ISSN: 2766-2276
419 Views 103 Downloads
Open Access Mini Review 12 Dec 2023

Interaction between Chronic Influenza and COVID-19: Novel Aspects of Immune System Combat

Iskakov BA*, Kaupenbayeva RB, Kypshakbayev AE and Siddikov M
This abstract provides an overview of two highly contagious viruses - influenza viruses and the COVID-19 virus, causing severe acute respiratory illness. The paper examines common and unique characteristics of the viruse…
Vol.4, Issue 12 10.37871/jbres1846 ISSN: 2766-2276
2,781 Views 111 Downloads
Open Access Original Article 26 Apr 2023

Research Progress on Anti-Tumor Mechanism of Tannins in Traditional Chinese Medicine

Hui Ding, Yuxin Wang, Gen Li, Yingling Dong, Xinyu Dai, Chenglong Kang, Kai Li, Haixing Han, Xuling Peng* and Xi Chen*
By reviewing the literature on the efficacy of tannins in traditional Chinese medicine in the last decade or so, we have classified the anti-tumor mechanism of tannins in conjunction with the latest mechanism exploration…
Vol.4, Issue 4 10.37871/jbres1736 ISSN: 2766-2276
1,857 Views 95 Downloads 3 Citations
Open Access Original Article 26 Jan 2023

The Effect of Montelukast in Children with Asthma Predictive Index Negative Episodic Viral Wheezing

Ayse Kirmizitas Aydogdu* and Cihan Fidan
Background: The effectiveness of montelukast for wheezing in young children is not clear. We aimed to evaluate whether the use of montelukast in the treatment of wheezing affects the number of attacks in children aged 1 …
Vol.4, Issue 1 10.37871/jbres1652 ISSN: 2766-2276
1,368 Views 100 Downloads
Open Access Research Article 30 Nov 2022

What Role Do Immunological and Inflammatory Biomarkers Play on Mortality and Exacerbations in COPD Patients?

Anna Maria Romanelli, Mauro Raciti, Angela Papa* and Renato Prediletto
Background: COPD phenotypes have been identified according to patient clinical characteristics and, more recently, to their immunological markers. However, the role of these biomarkers in relation to exacerbations in dif…
Vol.3, Issue 11 10.37871/jbres1615 ISSN: 2766-2276
704 Views 97 Downloads
Open Access Short Communication 14 Oct 2022

Monkeypox and Immunosuppressed Neurological Patients: What can we Advise Vaccination in Multiple Sclerosis and Neuromyelitis Optica Patients?

Lorna Galleguillos*
Monkeypox is a zoonotic viral disease that was identified in 1958 in research monkeys that came from Singapore. It is an orthopoxvirus that belongs to the Poxviridae family [1]. This viral infection was restricted to Afr…
Vol.3, Issue 10 10.37871/jbres1573 ISSN: 2766-2276
781 Views 67 Downloads 2 Citations
Open Access Research Article 23 Jul 2022

Environmental Surveillance of Poliovirus in Four Districts within Two Regions of Ghana

Ernest Obese-Djomoah, Evangeline Obodai, Emmanuel Gbevi, Ewurabena Duker, Keren Attiku, Miriam Eshun, Bismarck Boahene, Samuel Victor Nuvor and John Kofi Odoom*
The eradication of poliovirus is at its last phase through the efforts and strategies of Global Polio Eradication Initiation (GPEI). There are very few countries that are still endemic with Wild Poliovirus (WPV) and othe…
Vol.3, Issue 7 10.37871/jbres1514 ISSN: 2766-2276
1,594 Views 91 Downloads 2 Citations
Open Access Research Article 25 May 2022

Pan Cancer Insights into BAZ1B as a Prognostic and Immunological Marker

Xiaorong Zhao, Yuhu Niu, Qingjuan Li, Yuxuan Zhang and Bo Niu*
Background: The Bromodomain Adjacent to the Zinc Finger Domain 1B (BAZ1B) is a versatile nuclear protein. BAZ1B acts on chromatin remodeling, participates in DNA replication and damage repair, and is involved in RNA tran…
Vol.3, Issue 5 10.37871/jbres1487 ISSN: 2766-2276
1,065 Views 92 Downloads
Open Access Research Article 24 May 2022

Omicron Waves of the COVID-19 Pandemic and Efficacy of Vaccinations and Testing

Igor Nesteruk* and Oleksii Rodionov
The sharp increase in the number of new COVID-19 cases in late 2021 and early 2022, which occurred even in countries with high vaccination levels, has raised the question about the possibility of overcoming the pandemic …
Vol.3, Issue 5 10.37871/jbres1484 ISSN: 2766-2276
4,009 Views 99 Downloads 8 Citations
Open Access Original Article 16 Apr 2022

Analysis of Vitamin D and its Correlation with Interleukin-6 in COVID-19 Patients at Mary Begg Health Services, Zambia: Implication for Patient Management

Misheck Chileshe*, Mwamba Mulamba, Vernon Julius, Mwenya Kwangu and Stephen Mwisiya Mubita
Introduction: The emergence of SARS COV-2 and Coronavirus Disease 2019 (COVID-19) came without any known medication or treatment, thereby raising concerns for drug (therapeutics) research and development. Vitamin D is a …
Vol.3, Issue 4 10.37871/jbres1445 ISSN: 2766-2276
5,211 Views 100 Downloads 1 Citation
Open Access Research Article 17 Jan 2022

High Affinity Peptides in Processes of IgG Purification, Chromatographic Column Virus Inactivation/Elimination and Titer of Anti-Rubella IgG Enrichment

Serhiy P Havryliuk, Ievhenia M Krasnobryzha, Olena S Havryliuk and Heorgii L Volkov*
According to "The Proteome Code" concept introduced by J. Biro and our early development of affinity peptide calculation method it was studied the possibility of high affinity peptide chromatographic gels development for…
Vol.3, Issue 1 10.37871/jbres1399 ISSN: 2766-2276
2,180 Views 106 Downloads
Open Access Original Article 31 Dec 2021

Prevalence of Adverse Events Post-COVID-19 Vaccination amongst the Adult Zambian Population

Misheck Chileshe*, Geoffrey Mupeta, Maisa Kasanga, Ruth Lindizyani Mfune, Steward Mudenda, Mildred Biemba, Nzooma Munkwangu Shimaponda-Mataa, Musalula Sinkala and Victor Daka
Introduction: COVID-19 continues to be a public health concern despite several practical interventions to curb its spread. Now, widespread vaccination appears to be the most important strategy in winning the fight agains…
Vol.2, Issue 12 10.37871/jbres1389 ISSN: 2766-2276
20 Views 143 Downloads 3 Citations
Open Access Original Article 12 Nov 2021

Frequency of Gingivitis among 12 to 70 Years Old Patients Visiting Lady Reading Hospital, Peshawar, Pakistan: A Cross Sectional Study

Gulrukh Hamid, Asim Shahzad* and Abrar Hussain Mian
The present cross sectional study aimed to determine the frequency of gingivitis among 21 to 70 old patients at Periodontal Department of Lady Reading Hospital (LRH), Peshawar, Pakistan. A total of 133 patients were obse…
Vol.2, Issue 11 10.37871/jbres1350 ISSN: 2766-2276
2,045 Views 78 Downloads 1 Citation
Open Access Review Article 25 Aug 2021

Guillain-Barre Syndrome: Review and Summary

Mary Shannon Byers*
Guillain-Barré Syndrome is a life-threatening, demyelinating, autoimmune condition in which the body’s immune system attacks the myelin of the peripheral nervous system. Guillain-Barré Syndrome is characterized by as…
Vol.2, Issue 8 10.37871/jbres1297 ISSN: 2766-2276
3,331 Views 103 Downloads
Open Access Research Article 27 May 2021

Profile of Hepatitis B Sero Markers Among Blood Donors Attending Usmanu Danfodiyo University Teaching Hospital, Sokoto-Nigeria

Hussaini Mohammed Alhassan*, Saudetu Haruna Shinkafi, Ibrahim Yakubu, Hamisu Abdullahi, Ahmad Hamidu Marafa, Abdullahi Isiyaku and Mustapha Umar Kalgo
Introduction: Hepatitis B Virus (HBV) is a double-stranded circular DNA virus, it is one of the major blood transmissible infections. The prevalence of HBV is highest in sub-Saharan Africa and East Asia, where 5-20% of t…
Vol.2, Issue 5 10.37871/jbres1251 ISSN: 2766-2276
2,243 Views 100 Downloads 4 Citations
Open Access Original Article 04 May 2021

Determination of Serum IL-8, CD4+ and CD8+ in Patients with Human Immunodeficiency Virus

Hussaini Mohammed Alhassan*, Mohammed Haruna Yeldu, Mohammed Kabir, Muawiya Abubakar, Abdullahi Isiyaku, Mustapha Umar Kalgo, Ahmed Hamidu Marafa and Abdullahi Hamisu
Background: Human Immunodeficiency Virus (HIV) is associated with a decline of immunity and progression to Acquired Immunodeficiency Syndrome (AIDS). This current study was aimed at evaluating the serum level of Interleu…
Vol.2, Issue 5 10.37871/jbres1230 ISSN: 2766-2276
1,783 Views 60 Downloads
Open Access Commentary 21 Apr 2021

COVID-19 Vaccination and the Expanding Role of Pharmacists: Pharmacist - Immunization Program

Muhammad Ahmer Raza, Shireen Aziz, Shahid Masood Raza* and Sana Shahzad
Pharmacists in health systems involved with immunizations have used their practice settings to become advocates for immunization and increase their responsibilities in the public health monarchy. Administering vaccines t…
Vol.2, Issue 4 10.37871/jbres1227 ISSN: 2766-2276
8,837 Views 128 Downloads
Open Access Original Article 24 Nov 2020

Epithelial Cells Orchestrate the Functions of Dendritic Cells in Intestinal Homeostasis

Tianming Li, Mei Liu, Siyu Sun, Xuying Liu and Dongyan Liu*
The gastrointestinal tract represents the largest mucosal membrane surface and is the one of the most complex human organs. The intestinal barrier dysfunction contributes to systemic immune activation. The mucosal immune…
Vol.1, Issue 7 10.37871/jbres1165 ISSN: 2766-2276
5,420 Views 667 Downloads 1 Citation
Open Access Letter to Editor 12 Jun 2020

Recommendations for Individualized Rehabilitation of Syncope in Children and Adolescents during the COVID-19 Epidemic

Xin Wang, Haihui Xiao, Yi Xu and Cheng Wang*
Since December 2019, the outbreak of SARS-CoV-2 in WuHan, HuBei province, has spread to the whole country and abroad. As a susceptible population, the number of children and adolescents is increasing day by day. Under th…
Vol.1, Issue 2 10.37871/jels1115 ISSN: 2766-2276
1,214 Views 490 Downloads 1 Citation
Open Access Short Communication 26 May 2020

Analysis of Reported Case Fatality Rate and Characteristics of COVID-19 Patients in Italy

Alireza Hamidian Jahromi
In a recent viewpoint publication in the Journal of American Medical Association (JAMA), Onder, et al. provided insight into the coronavirus disease 2019 (COVID-19) outbreak in Italy along with an explanation of the Ital…
Vol.1, Issue 1 10.37871/jels1111 ISSN: 2766-2276
3,056 Views 1,081 Downloads

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