Clinical Cardiology
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Clinical CardiologyThese topics are filtered from our journals helping to discover the community within the widespread of multi-disciplinary Have a look at this page once and make your article more discoverable in our esteemed journal to ensuring readers find your article through search engines such as Google.
Research Articles
45 articles
Open Access
Short Communication 19 Jul 2026
Early-Onset Myocardial Infarction in Young Adults (18-30 Years): A Multisystem Pathophysiological Disorder beyond Premature Atherosclerosis
Myocardial Infarction (MI) in young adults aged 18–30 years is an emerging clinical concern with a steadily increasing global incidence. Although traditionally attributed to premature atherosclerosis, growing evidence su…
43 Views
Open Access
Research Article 29 Apr 2026
Down-Regulation of Ephrin-B1 in Left Ventricular Non-Compaction
Background: Left Ventricular Non-Compaction (LVNC) is a rare cardiomyopathy with incompletely understood pathophysiological mechanisms. Ephrin-B1 (Ep), a key protein of cardiomyocyte lateral junctions, may play a role in…
34 Views 54 Downloads
Open Access
Review Article 11 Nov 2025
Keto Diet May Worsen Coronary Artery Disease: Insights from Bethsaida Hospital’s Plant-Based Diet Experience
The ketogenic (keto) diet, characterized by high fat, moderate protein, and minimal carbohydrate intake, has surged in popularity due to its perceived efficacy in rapid weight loss. Nevertheless, accumulating evidence hi…
766 Views 64 Downloads
Open Access
Perspective 19 Aug 2025
Artificial Intelligence and Robotics in Interventional Cardiology: Preparing for a Transformative Future
Cardiovascular Disease (CVD) remains the leading cause of death worldwide, despite significant advances in pharmacotherapy and interventional techniques. The emergence of Artificial Intelligence (AI) and robotics represe…
36 Views 84 Downloads
Open Access
Review Article 11 Aug 2025
Why we avoid Animal Products: Science and Success Behind Bethsaida Hospitals Whole-Food Plant-Based Cardiac Program
Cardiovascular disease remains the leading cause of morbidity and mortality globally, with atherosclerosis and restenosis as critical pathological contributors. Accumulating evidence suggests that diets high in animal pr…
338 Views 77 Downloads
Open Access
Perspective 11 Aug 2025
Harnessing Nutrition to Prevent Coronary Recoil in Drug-Coated Balloon Angioplasty: Insights from Bethsaida Hospital
The success of Drug-Coated Balloon (DCB) angioplasty hinges critically on effectively preventing coronary artery recoil, an acute elastic response that threatens procedural efficacy and long-term vessel patency. While te…
544 Views 79 Downloads
Open Access
Opinion 09 Jul 2025
Cracks in the Evidence: Why Studies from COURAGE to ISCHEMIA Failed to Show Benefit of Stenting PCI
Percutaneous Coronary Intervention (PCI) with stenting remains widely utilized for managing Chronic Coronary Syndrome (CCS). However, landmark clinical trials such as COURAGE and ISCHEMIA have repeatedly shown no signifi…
633 Views 74 Downloads
Open Access
Perspective 30 Jun 2025
Transforming Cardiac Care through Plant-Based Diets: A Breakthrough Experience from Bethsaida Hospital, Indonesia
Seven years ago, at Bethsaida Hospital in Indonesia, Professor Dasaad Mulijono pioneered the integration of a Plant-Based Diet (PBD) into routine cardiac caresa paradigm shift that has dramatically improved outcomes for …
609 Views 85 Downloads
Open Access
Review Article 16 Jun 2025
Modulation of Inflammation in Cardiac Function after Myocardial Infarction
521 Views 77 Downloads 1 Citation
Open Access
Case Series 14 May 2025
Multivessel Minimally Invasive Coronary Bypass with Aortic Crossclamp. Experience with 40 First Patients
Background: Minimally Invasive Coronary Revascularization (MICS-CABG) has been performed for over 20 years; however, their technical complexity, steep learning curves and absence of training programs explain the weak acc…
391 Views 75 Downloads
Open Access
Short Communication 12 May 2025
Autologous Angiogenic Cell Precursors- A Molecular Strategy for The Treatment of Heart Failure: Response to Biocardia’s Cardiamp HF Trial
525 Views 87 Downloads 1 Citation
Open Access
Perspective 24 Apr 2025
How a Plant-Based Diet and Ultra-Low LDL Levels Can Reverse Atherosclerosis and Prevent Restenosis: A Breakthrough in Heart Health
Low-Density Lipoprotein Cholesterol (LDL-C) remains a key target in preventing and treating cardiovascular disease. Recent data and expert consensus increasingly support aggressive LDL-C lowering strategies, with emergin…
1,878 Views 96 Downloads 1 Citation
Open Access
Case Report 26 Nov 2024
Tricuspid Stenosis of a Complex Etiology in a 26-Year-Old Woman after Surgical Correction of Congenital Gerbode Defect, successfully treated with Percutaneous Balloon Valvuloplasty
Adults with Congenital Heart Disease (ACHD) are a constantly growing population that often presents significant challenges and requires a multidisciplinary approach. Therapeutic decisions must balance potential benefits …
217 Views 136 Downloads
Open Access
Case Report 30 Sep 2024
Stroke as the First Sign of Heart Tumor What the Neurologist should know about Heart
Primary heart cancers are rare, but cancer metastases occur much more often, which is why they are diagnosed mainly in non-oncology departments. Approximately 85% of heart cancers are benign, with myxoma predominating [1…
190 Views 119 Downloads
Open Access
Case Report 24 Jul 2024
Postural Orthostatic Tachycardia Syndrome (POTS) of Autoimmune Origin - Case and Review
Introduction: Postural Orthostatic Tachycardia Syndrome (POTS) belongs to a group of orthostatic intolerance syndromes. It is defined by the increase in heart rate ≥30 bpm or heart rate higher than 120/min during first…
3,072 Views 116 Downloads 2 Citations
Open Access
Research Article 26 Feb 2024
Initial Clinical Experience with New Technology ePatchTM Extended Holter Monitoring
Introduction and objectives: Conventional methods of Holter (H) monitoring, data analysis and reporting can be inefficient, leading to high costs and long response times. Traditional H devices can be cumbersome to wear, …
4,278 Views 104 Downloads 1 Citation
Open Access
Research Article 17 Jan 2024
Risk Factors for Early Bioprosthetic Heart Valve Degeneration in Patients with Rheumatic Fever
Background: Rheumatic Fever (RF) is an immunological disorder related to exposure to group a streptococcus and rheumatic heart disease is an important cause of valve replacement. Bioprosthetic valves tend to degenerate f…
1,136 Views 112 Downloads
Open Access
Short Communication 05 Jan 2024
Analysis of the Impact of Tourmaline and Terahertz-Infused Clothing on Heart Rate Variability
Introduction: Expanding upon prior investigations that identified advantageous Far Infrared (FIR) properties associated with two minerals, namely tourmaline and terahertz, across diverse domains, including health and med…
6,715 Views 128 Downloads
Open Access
Research Article 12 Dec 2023
The Value of Fetal Echocardiography for Early Detection of Congenital Heart Defects: A Report of our Experience in a Great Referral Heart Center in Iran
Background: Prenatal diagnosis of cardiac defects in fetus is of paramount importance to enable a better monitoring of heart defects and to allow planning a proper management. We reported our experience on fetal heart ec…
2,392 Views 94 Downloads
Open Access
Mini Review 14 Nov 2023
Hypoxic Epicardium Contribution to Myocardial Repair
Epicardium, the outer epithelial layer of the heart forming from extracardiac primordium, plays a fundamental role in myocardial embryogenesis by generating epicardial-derived cells (cardiac fibroblasts, mesenchymal cell…
737 Views 100 Downloads
Open Access
Research Article 25 Oct 2023
TDI Analysis as Predictor of Positive Perugini Score in HFpEF Patients with Restrictive Phenotype
Cardiac amyloidosis is an important but underdiagnosed cause of heart failure with preserved ejection fraction (HFpEF). We analysed TDI doppler with echo to determine if there is a correlation with positive results in my…
751 Views 126 Downloads
Open Access
Short Communication 19 May 2023
Subclinical Paroxystic Atrial Fibrillation after Stroke
Stroke is a pathology with great social repercussion, since it is the second cause of mortality in the world and the first cause of dependency in adults [1].…
561 Views 82 Downloads
Open Access
Review Article 30 Mar 2023
Relationship between Ischemic Stroke and Atrial Fibrillation, Systematic Review
Introduction: Atrial Fibrillation (AF) is not only one of the main causes of stroke, but it is also the most common sustained cardiac arrhythmia. As a result of population aging, an increase in the prevalence of AF and o…
447 Views 94 Downloads
Open Access
Review Article 29 Mar 2023
Ischemic Stroke of Cardioembolic Origin Systematic Review
Ischemic stroke corresponds to 80% of cases in Brazil, which demonstrates the epidemiological importance in Brazil. The magnitude of this fact reflects the reason why stroke is considered the second cause of death in the…
1,026 Views 89 Downloads
Open Access
Rapid Communication 05 Jan 2023
ASSUMER on PYP Scan for Cardiac Amyloid Typing and Origin: Case-Specific Corroborating Clinical Background and Genetic Analysis
Suspicion for Cardiac Amyloidosis (CA) led a 75-year-old male patient with fatigue, dyspnea, and palpitations to be subjected to scintigraphic myocardial investigation with technetium-99m-pyrophosphate (99mTc-PYP, or PYP…
806 Views 98 Downloads
Open Access
Mini Review 04 Jan 2023
Molecular Imaging in Oncocardiology
Cancer and Cardiovascular Disease (CVD) are the most common causes of death and disability in many countries. Cancer and CVD are closely related in terms of both scientific and clinical perspectives. Oncocardiology has r…
565 Views 110 Downloads
Open Access
Case Report 28 Nov 2022
Cancer Patient was attacked by Thrombosis: Case Report
Background: Cancer is the second leading cause of mortality after cardiovascular disease. The second common leading cause of mortality in cancer patients is thrombosis, vary from arterial or venous thromboembolism to dis…
771 Views 79 Downloads
Open Access
Case Report 28 Nov 2022
Successful 4-Year Outcome Following Convergent Ablation for Longstanding Persistent Atrial Fibrillation in an Octogenarian – Novel Therapy for an Old Condition in the Very Elderly
The most common age range for Atrial Fibrillation (AF) prevalence over the coming decades will potentially be in those over 75 years old. However, despite widespread recognition of the strong association between AF burde…
770 Views 70 Downloads
Open Access
Research Article 27 Oct 2022
Research Progress on the Correlation between Hyperhomocysteinemia and Arteriosclerosis Obliteran
Arteriosclerosis Obliteran (ASO) is a local manifestation of systemic arteriosclerosis in the lower extremity arteries. ASO is a chronic progressive disease caused by arteriosclerosis, such as intimal thickening, lumen s…
1,548 Views 78 Downloads 1 Citation
Open Access
Research Article 26 Oct 2022
Effect of Fastigial Nucleus Stimulation on Serum Inflammatory Factors in Patients with Coronary Heart Disease
Objective:
To observe the effect of Fastigial Nucleus Stimulation (FNS) on serum inflammatory
factors in patients with coronary heart disease.
Methods: 144 patients with coronary heart disease were randomly divi…
734 Views 86 Downloads
Open Access
Case Report 26 Oct 2022
Unusual Thrombosis Despite Anticoagulation
Background: Pulmonary Embolism (PE) is a life-threatening condition with annual incidence ranging from 39 to 115 cases per 100,000 population [1]. Along with many other causes, neoplasia is one of the highest risk factor…
991 Views 79 Downloads
Open Access
Research Article 30 Sep 2022
Predictors of Acute Response to Cardiac Resynchronization Therapy in Cardiomyopathy Patients
Background: Usefulness of echocardiogram-associated markers for prediction of the response of the patients with cardiomyopathy to Cardiac Resynchronization Therapy (CRT) is under debate.Method: In a cross sectional retro…
688 Views 81 Downloads
Open Access
Case Report 24 May 2022
Perfect is the Enemy of the Good: Outflow Tract Rupture During Self-Expandable Transcatheter Aortic Valve Implantation
Annular rupture is an ambiguous term that refers to a series of infrequent but life-threatening transcatheter aortic valve replacement complications associated with anatomical and clinical risk factors that often require…
1,225 Views 86 Downloads
Open Access
Research Article 30 Apr 2022
Pathophysiology, Treatment and Long-Term Consequences of Heart Failure in Infancy
Introduction: Infants have the highest risk to die from heart failure. However, innovations like beta-blocker treatment introduced more than 50 years ago are not recorded in the guidelines if the clinical trials are miss…
1,496 Views 88 Downloads
Open Access
Review Article 26 Apr 2022
Exposure to Urban Air Pollution Nanoparticles: Oxidative Stress and Cardiovascular Disease
It is estimated that more than two-thirds of air pollution-related deaths are due to cardiovascular causes. Significant studies have now indicated that exposure to urban air pollutants is known to be a source of oxidativ…
3,262 Views 89 Downloads 3 Citations
Open Access
Review Article 16 Apr 2022
Association of Myocardial Infarction Among Cervical Cancer Patients
Introduction: Increased risk of myocardial infarction has been validated for several cancers, but limited study evaluated this risk in cervical cancer patients. Our study aimed to evaluate the risk of myocardial infarcti…
1,866 Views 51 Downloads
Open Access
Case Report 08 Mar 2022
Lead Extraction and Re-Extractions - Inherent Parts of Permanent Pacing in Children and Young Adults
Children require often replacement of leads even several times. Repeated extraction in this group nay be challenging. We report the case of a 22-year-old man with the first pacemaker implanted in the first year of life, …
2,354 Views 86 Downloads 3 Citations
Open Access
Clinical Image 09 Sep 2021
Reflection on the benignity or pathology of the presence of U waves in the electrocardiogram
We present the electrocardiogram (Figure 1) of a 14-year-old man in which, without related pathology, and incidentally in the context of a consultation for another reason, a U wave was detected in precordial leads V3 and…
2,386 Views 70 Downloads
Open Access
Case Report 29 Jun 2021
Inducible Atrial Fibrillation and Myocardial Ischemia in a Veteran Amateur Runner: An Anecdotal Case Report
Atrial fibrillation is the most common sustained cardiac arrhythmia and is associated with significant morbidity and mortality. Coronary artery disease frequently coexists with AF, and management of these associated cond…
1,715 Views 141 Downloads
Open Access
Research Article 08 Jun 2021
Clinical Appearance and Diagnosis of Heparin Induced Thrombocytopenia
Heparin-Ä°nduced Thrombocytopenia (HIT) is a life-threatening complication that occurs in a small percentage of exposed patients (e.g. unfractionated heparin, Low Molecular Weight Heparin [LMWH]) regardless of dose and t…
1,133 Views 89 Downloads
Open Access
Research Article 20 May 2021
Neutrophil to Lymphocyte Ratio Reflects the Proteolytic Activity of the Abdominal Aortic Aneurysm Wall
Background: This study aims to evaluate the local proteolytic activity from the level of Abdominal Aortic Aneurysm (AAA) wall and correlate the obtained values with the preoperative values of NLRs (Neutrophil-Lymphocyte …
1,554 Views 77 Downloads
Open Access
Commentary 11 May 2021
Erroneous Recording of Maternal Heart Rate as Fetal Heart Rate During Second Stage of Labour: Isn’t it Time to Stop this?
Electronic Fetal Heart Rate (FHR) monitoring is recommended to assess fetal well-being during labour in high risk pregnancies. This Cardiotocograph (CTG) monitoring relies on the ultrasound technology with the limitation…
6,866 Views 130 Downloads 9 Citations
Open Access
Original Article 18 Mar 2021
Potential Use of Quercetin as Protective Agent against Hydroxychloroquine Induced Cardiotoxicity
The aim of this study is to investigate the protective effects of Quercetin (QCT) on Hydroxychloquine (HCQ)-induced myocardial affection in rats. HCQ has been found to produce toxic effects including cardiac manifestatio…
3,417 Views 66 Downloads 4 Citations
Open Access
Case Report 29 Jan 2021
Triggered by Covid-19? Large Vascular Occlusion Resulting in Cytokine Storm Syndrome and Kounis Syndrome: A Case Report
It has been widely reported that infections caused by coronaviruses, especially SARS-CoV-2 (Covid-19), can result in cytokine storm syndrome, one of the causes of acute cerebrovascular disease and ‘kounis syndrome’. …
1,873 Views 384 Downloads 1 Citation
Open Access
Editorial 11 Jan 2021
Multifaceted Medical and Scientific Approaches and the Role of the Public in Combating the COVID-19 Pandemic in the Digital Era
Epidemics and pandemics have been recurrent in history. One of the worst pandemics in the modern history was the 1918 H1N1 flu (“Spanish fluâ€) that claimed the lives of an estimated 50 million people globally [1]. Th…
5,616 Views 292 Downloads
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