Preparation and Characterization of 3-Amino- 1H-1,2,4-Triazole Grafted on the Surface of Silica Nanoparticles Support (SNPs-AT ) for the Synthesis of Pyrano[2,3-c]Pyrazole Derivatives as the Novel, Effective, and Reclaimable Catalyst

Pourkazemi A*; Karami B; Farahi M

**Pourkazemi A*, Karami B and Farahi M**

Volume6-Issue7
Dates: Received: 2025-09-13 | Accepted: 2025-09-17 | Published: 2025-09-19
Pages: 1290-1301

Abstract

The main objective of the current research, 3-amino-1H‐1,2,4‐triazole immobilized on 3-chloropropyl joined SiO2 nanoparticles as a recyclable, environment-friendly, and novel heterogeneous base catalyst. It was characterized by fourier transform infrared, X-ray diffraction patterns, field emission scanning electron microscopes, and energy-dispersive X-ray spectroscopy. This new material as a green and efficient catalyst was used for the synthesis of pyrano [2,3-c]pyrazoles derivatives through the reaction of aromatic aldehydes, malononitrile, and 3-methyl-1-phenyl-2-pyrazoline-5-one. The reactions did in solvent-free conditions at 60°C and the related pyran derivatives prepared in excellent yields. Also, this catalyst could be used several times without decreasing the activity.

FullText HTML FullText PDF DOI: 10.37871/jbres2184

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Pourkazemi A, Karami B, Farahi M. Preparation and Characterization of 3-Amino- 1H‐1,2,4‐Triazole Grafted on the Surface of Silica Nanoparticles Support (SNPs-AT ) for the Synthesis of Pyrano[2,3-c]Pyrazole Derivatives as the Novel, Effective, and Reclaimable Catalyst. J Biomed Res Environ Sci. 2025 Sept 19; 6(9): 1290-1301. doi: 10.37871/jbres2184, Article ID: JBRES2184, Available at: https://www.jelsciences.com/articles/jbres2184.pdf

Subject area(s)

Organic Chemistry

Material Science

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