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Spontaneous Breast Hematoma Induced by Vitamin K Antagonist Therapy: A Case Report

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Open Access
Article Type Case Report
Subject Medicine Group
OCLC JBRES Record
Amri M*, Altimimi A, Boudar A, Asklou A, Azzouzi L and Habbal R
Issue: Volume5-Issue8
Pages: 1063-1066
Received: 2024-07-31
Accepted: 2024-08-30
Published: 2024-08-31

Abstract

Anticoagulant medications, particularly Vitamin K Antagonists (VKAs), are essential for managing thrombotic conditions but can cause severe side effects such as spontaneous hematomas. This case report describes a 69-year-old woman on VKA therapy who developed a large right breast hematoma. Immediate suspension of VKA, blood transfusions, and vitamin K administration led to clinical improvement. Breast ultrasonography confirmed the diagnosis, and after a week, the hematoma regressed, allowing for the resumption of anticoagulation with unfractionated heparin. This case highlights the need for careful monitoring and management of VKA therapy, especially in elderly patients.

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© 2024 Amri M. Distributed under Creative Commons CC-BY 4.0 Creative CommonsAttribution

How to cite this article

Amri M, Altimimi A, Boudar A, Asklou A, Azzouzi L, Habbal R. Spontaneous Breast Hematoma Induced by Vitamin K Antagonist Therapy: A Case Report. J Biomed Res Environ Sci. 2024 Aug 31; 5(8): 1063-1066. doi: 10.37871/jbres1989, Article ID: JBRES1989, Available at: https://www.jelsciences.com/articles/jbres1989.pdf

Subject area(s)

HematologyBlood Disorders

References

  1. Kayaalp SO. Medical pharmacology for rational treatment. Ankara: Pelikan Publishing. 2012.
  2. Yang JC, Makaryus AN. Warfarin Anticoagulation and Spontaneous Pectoral Haematomas. Heart Lung Circ. 2016 Jul;25(7):e81-4. doi: 10.1016/j.hlc.2015.10.022. Epub 2016 Feb 8. PMID: 26948766.
  3. Gani I, Kapoor R, Saeed M. Spontaneous Breast Haematoma after Heparin Anticoagulation. Eur J Case Rep Intern Med. 2020 Jun 11;7(9):001735. doi: 10.12890/2020_001735. PMID: 32908833; PMCID: PMC7473684.
  4. Patel N, Baker SM, Modrykamien A. Hemorrhagic shock due to spontaneous pectoral hematoma associated with anticoagulation therapy. J Gen Intern Med. 2013 Dec;28(12):1673. doi: 10.1007/s11606-013-2451-z. Epub 2013 May 1. PMID: 23636915; PMCID: PMC3832720.
  5. Shakerian B, Razavi N. Warfarin-Induced Spontaneous Bilateral Breast and Extrathoracic Hematoma in an Elderly Woman. J Tehran Heart Cent. 2020 Apr;15(2):84-85. doi: 10.18502/jthc.v15i2.4190. PMID: 33552201; PMCID: PMC7825465.
  6. Gündeş E, Değer KC, Taşcı E, Senger AS, Duman M. Anticoagulant-induced breast hematoma. Ulus Travma Acil Cerrahi Derg. 2017 Jan;23(1):72-73. doi: 10.5505/tjtes.2016.01657. PMID: 28261775.
  7. Beyth RJ, Landefeld CS. Anticoagulants in older patients. A safety perspective. Drugs Aging. 1995 Jan;6(1):45-54. doi: 10.2165/00002512-199506010-00004. Erratum in: Drugs Aging 1995 Apr;6(4):343. PMID: 7696778.
  8. Patel MR. The role of antiplatelet therapy in the management of cardiovascular disease. American Journal of Cardiology. 2011;108(1):24-33.
  9. Lanas A. NSAID-induced gastrointestinal damage and the role of proton pump inhibitors. Nature Reviews Gastroenterology & Hepatology. 2011;8(8):481-493.
  10. Maree AO. The effect of antibiotic therapy on the INR in patients on stable warfarin therapy. Journal of Clinical Pharmacy and Therapeutics. 2010;35(5):499-504.
  11. Benbouchta K, Mrabet A, Kallel O, El Ouafi N, Bazid Z. Spontaneous massive pectoral hematoma induced by vitamin K antagonist therapy: a case report. Pan Afr Med J. 2021 Apr 1;38:324. doi: 10.11604/pamj.2021.38.324.28454. PMID: 34285747; PMCID: PMC8265252.
  12. Ming-Yang Li, Xiao-Ping Li, Hai-Xian Ren, Shi-Hui Tang, Booreddy S, Can-Can Zhang, Zhi-Jun Tan. Rivaroxaban-induced breast spontaneous hematoma: A case report. Int J Clin Exp Med. 2018;11(6):6378-6382.
  13. Gani I, Kapoor R, Saeed M. Spontaneous Breast Haematoma after Heparin Anticoagulation. Eur J Case Rep Intern Med. 2020 Jun 11;7(9):001735. doi: 10.12890/2020_001735. PMID: 32908833; PMCID: PMC7473684.
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