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Ultrastructural Changes in Brain Tissue in Drug-Resistant Mesial Temporal Lobe Epilepsy in Humans: A Mini-Review

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Open Access
Article Type Mini Review
Subject Medicine Group
OCLC JBRES Record
Darya Sitovskaya* and Yulia Zabrodskaya
Issue: Volume4-Issue11
Pages: 1570-1574
Received: 2023-11-03
Accepted: 2023-11-13
Published: 2023-11-17

Abstract

Epilepsy is a group of chronic neurological diseases of the brain characterized by a persistent predisposition to epileptic seizures, affecting more than 70 million people worldwide. Drug-resistance is a key problem in the theory and practice of epileptology. The literature contains many publications devoted to ultrastructural changes in brain tissue in experimental animal models, but the features of ultrastructural changes in human brain tissue in drug-resistant mesial Temporal Lobe Epilepsy (TLE) remain unknown. This brief review presents the current state of the art of problems devoted to the study of the ultrastructure of neurons, glia, and blood vessels in patients with drug-resistant mesial TLE.

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© 2023 Sitovskaya D, et al. Distributed under Creative Commons CC-BY 4.0 Creative CommonsAttribution

How to cite this article

Sitovskaya D, Zabrodskaya Y. Ultrastructural Changes in Brain Tissue in Drug-Resistant Mesial Temporal Lobe Epilepsy in Humans: A Mini-Review. J Biomed Res Environ Sci. 2023 Oct 17; 4(11): 1570-1574. doi: 10.37871/jbres1831, Article ID: JBRES1831, Available at: https://www.jelsciences.com/articles/jbres1831.pdf

Subject area(s)

Brain DisordersNeurological Disorders

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