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Prevalence, Predictors and Diagnosis of Cardiac Amyloidosis in Patients with Aortic Stenosis

Journal of Biomedical Research & Environmental Sciences article abstract with citation details, DOI, publication dates, subject areas, full text links, and references.

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Open Access
Article Type Mini Review
Subject Medicine Group
OCLC JBRES Record
Syed Bukhari*
Issue: Volume4-Issue9
Pages: 1277-1280
Received: 2023-08-26
Accepted: 2023-09-12
Published: 2023-09-13

Abstract

Cardiac amyloidosis and aortic stenosis often share a common clinical phenotype, and are associated with morbidity and mortality if untreated. Cardiac amyloidosis is present in ~15% of patients with aortic stenosis. Clinical suspicion for cardiac amyloidosis in aortic stenosis is often raised based on history (bilateral carpal tunnel syndrome, severe lumbar spinal stenosis, spontaneous biceps rupture), chronic troponin elevation, electrocardiographic features (low-voltage criteria, pseudoinfarct pattern), echocardiogram (bilateral ventricular hypertrophy, abnormal longitudinal strain) and magnetic resonance imaging (late gadolinium enhancement, elevated T1 and T2). Eventual diagnosis of cardiac amyloidosis is based either on pyrophosphate nuclear scintigraphy or tissue biopsy depending on which subtype of cardiac amyloidosis is suspected.

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© 2023 Bukhari Syed. Distributed under Creative Commons CC-BY 4.0 Creative CommonsAttribution

How to cite this article

Bukhari S. Prevalence, Predictors and Diagnosis of Cardiac Amyloidosis in Patients with Aortic Stenosis. 2023 Sep 13; 4(9): 1277-1280. doi: 10.37871/jbres1796, Article ID: JBRES1796, Available at: https://www.jelsciences.com/articles/ jbres1796.pdf

Subject area(s)

Cardiovascular Diseases

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