Comparison of Assisted Reproductive Technology (ART) Outcomes between Fasting during Ramadan, Pre and Post Ramadan Patients: A Retrospective Study

Soheila Pourmasumi; Parvin Sabeti*

Soheila Pourmasumi and Parvin Sabeti*

Volume4-Issue8
Dates: Received: 2023-07-29 | Accepted: 2023-08-07 | Published: 2023-08-10
Pages: 1179-1183

Abstract

Background: Infertility is a problem that affected all aspect of life in couples. Infertility treatment create stressful condition for patients and control of this stress is effective for success rate of pregnancy. Ramadan is a holy month for Muslims and they believe that Ramadan can effect on their spiritual lives and they become closer to God. So we think that maybe Assisted Reproductive Technology (ART) outcomes improve in the fasting patients during Ramadan. The aim of this study was to evaluate the outcome of ART in fasting patients during Ramadan and compare with non-fasting pre and post Ramadan.

Methods: In this retrospective study, we reviewed the demographic, clinical and laboratory records of 367 patients who were in treatment plan in Ramadan, 424 patients in pre and 386 in post Ramadan. All data including Age, number of retrieved oocytes, matured oocytes, types of ART procedures, number of fertilized oocytes, number of transferred embryo, pregnancy rates were collected from the hospital records. The data analyzed by SPSS v 16. The level of significance was p < 0.05.

Results: We analyzed 1177 case in 3 groups. There was an increase in the ART outcomes including Number of COC, oocyte, ET and pregnancy rate, however, this difference was not statistically significant.

Conclusion: Although, positive results were slightly higher in Ramadan, but it was not statistically significant. We conclude that fasting during Ramadan has no significant negative effect on the outcomes of ART. More studies needed to evaluate hormonal and psychological parameters in ART patients during Ramadan.

FullText HTML FullText PDF DOI: 10.37871/jbres1784

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How to cite this article

Pourmasumi S, Sabeti P. Comparison of Assisted Reproductive Technology (ART) Outcomes between Fasting during Ramadan, Pre and Post Ramadan Patients: A Retrospective Study. 2023 Aug 10; 4(8): 1179-1183. doi: 10.37871/jbres1784, Article ID: JBRES1784, Available at: https://www.jelsciences.com/articles/jbres1784.pdf

Subject area(s)

Gynecology

Reproductive Medicine

References

Vander Borght M, Wyns C. Fertility and infertility: Definition and epidemiology. Clin Biochem. 2018 Dec;62:2-10. doi: 10.1016/j.clinbiochem.2018.03.012. Epub 2018 Mar 16. PMID: 29555319.
Kazemijaliseh H, Ramezani Tehrani F, Behboudi-Gandevani S, Hosseinpanah F, Khalili D, Azizi F. The Prevalence and Causes of Primary Infertility in Iran: A Population-Based Study. Glob J Health Sci. 2015 Apr 19;7(6):226-32. doi: 10.5539/gjhs.v7n6p226. PMID: 26153187; PMCID: PMC4803880.
Meyers M, Diamond R, Kezur D, Scharf C, Weinshel M, Rait DS. An infertility primer for family therapists: I. Medical, social, and psychological dimensions. Fam Process. 1995 Jun;34(2):219-29. doi: 10.1111/j.1545-5300.1995.00219.x. PMID: 7589419.
Zargar AH, Wani AI, Masoodi SR, Laway BA, Salahuddin M. Epidemiologic and etiologic aspects of primary infertility in the Kashmir region of India. Fertil Steril. 1997 Oct;68(4):637-43. doi: 10.1016/s0015-0282(97)00269-0. PMID: 9341602.
Damti OB, Sarid O, Sheiner E, Zilberstein T, Cwikel J. [Stress and distress in infertility among women]. Harefuah. 2008;147(3):256-260.
Boivin J, Schmidt L. Infertility-related stress in men and women predicts treatment outcome 1 year later. Fertil Steril. 2005 Jun;83(6):1745-52. doi: 10.1016/j.fertnstert.2004.12.039. PMID: 15950646.
Bellone M, Cottencin O, Rigot JM, Goudemand M. [Study on psychiatric disorders and defensive process assessed by the "defense style questionnaire" in sterile males SAMPLE consulting in andrology]. Encephale. 2005;31(4 Pt 1):414-425.
Musa R, Ramli R, Yazmie AW, Khadijah MB, Hayati MY, Midin M, Nik Jaafar NR, Das S, Sidi H, Ravindran A. A preliminary study of the psychological differences in infertile couples and their relation to the coping styles. Compr Psychiatry. 2014 Jan;55 Suppl 1:S65-9. doi: 10.1016/j.comppsych.2013.01.001. Epub 2013 Feb 19. PMID: 23433218.
Kato T. Frequently Used Coping Scales: A Meta-Analysis. Stress Health. 2015 Oct;31(4):315-23. doi: 10.1002/smi.2557. Epub 2013 Dec 12. PMID: 24338955.
Agli O, Bailly N, Ferrand C. Spirituality and religion in older adults with dementia: a systematic review. Int Psychogeriatr. 2015 May;27(5):715-25. doi: 10.1017/S1041610214001665. Epub 2014 Aug 26. PMID: 25155440.
Meo SA, Hassan A. Physiological changes during fasting in Ramadan. J Pak Med Assoc. 2015 May;65(5 Suppl 1):S6-S14. PMID: 26013791.
Etemadifar M, Sayahi F, Alroughani R, Toghianifar N, Akbari M, Nasr Z. Effects of prolonged fasting on fatigue and quality of life in patients with multiple sclerosis. Neurol Sci. 2016 Jun;37(6):929-33. doi: 10.1007/s10072-016-2518-9. Epub 2016 Mar 19. PMID: 26994616.
Farooq A, Herrera CP, Almudahka F, Mansour R. A Prospective Study of the Physiological and Neurobehavioral Effects of Ramadan Fasting in Preteen and Teenage Boys. J Acad Nutr Diet. 2015 Jun;115(6):889-97. doi: 10.1016/j.jand.2015.02.012. Epub 2015 Apr 1. PMID: 25840939.
Kiyani MM, Memon AR, Amjad MI, Ameer MR, Sadiq M, Mahmood T. Study of Human Biochemical Parameters During and After Ramadan. J Relig Health. 2017 Feb;56(1):55-62. doi: 10.1007/s10943-015-0084-8. PMID: 26149778.
Pallayova M, Zaghloul HB, Arora T, Choudhury SM, Omar OM, Chagoury OL, Taheri S. Investigating physiological glucose excursions before, during, and after Ramadan in adults without diabetes mellitus. Physiol Behav. 2017 Oct 1;179:110-115. doi: 10.1016/j.physbeh.2017.05.032. Epub 2017 May 31. PMID: 28577886.
Sagy I, Zeldetz V, Halperin D, Abu Tailakh M, Novack V. The effect of Ramadan fast on the incidence of renal colic emergency department visits. QJM. 2017 Sep 1;110(9):571-576. doi: 10.1093/qjmed/hcx079. PMID: 28419353.
Wahba KA. Effect of fasting of Ramadan on infertile women undergoing in-vitro fertilization/intracytoplasmic sperm injection cycles: A Prospective Cohort Study. Open Journal of Obstetrics and Gynecology. 2016;6(3):171. doi: 10.4236/ojog.2016.63022.
Attarzadeh Hosseini SR, Hejazi K. The effects of ramadan fasting and physical activity on blood hematological-biochemical parameters. Iran J Basic Med Sci. 2013 Jul;16(7):845-9. PMID: 23997915; PMCID: PMC3758056.
Yavangi M, Amirzargar MA, Amirzargar N, Dadashpour M. Does Ramadan fasting has any effects on menstrual cycles? Iran J Reprod Med. 2013 Feb;11(2):145-50. PMID: 24639740; PMCID: PMC3941357.
Baynouna Al Ketbi LM, Niglekerke NJ, Zein Al Deen SM, Mirghani H. Diet restriction in Ramadan and the effect of fasting on glucose levels in pregnancy. BMC Res Notes. 2014 Jun 24;7:392. doi: 10.1186/1756-0500-7-392. PMID: 24962444; PMCID: PMC4088297.
Glazier JD, Hayes DJL, Hussain S, D'Souza SW, Whitcombe J, Heazell AEP, Ashton N. The effect of Ramadan fasting during pregnancy on perinatal outcomes: a systematic review and meta-analysis. BMC Pregnancy Childbirth. 2018 Oct 25;18(1):421. doi: 10.1186/s12884-018-2048-y. PMID: 30359228; PMCID: PMC6202808.
Awwad J, Usta IM, Succar J, Musallam KM, Ghazeeri G, Nassar AH. The effect of maternal fasting during Ramadan on preterm delivery: a prospective cohort study. BJOG. 2012 Oct;119(11):1379-86. doi: 10.1111/j.1471-0528.2012.03438.x. Epub 2012 Jul 25. PMID: 22827751.
Litzky JF, Marsit CJ. Epigenetically regulated imprinted gene expression associated with IVF and infertility: possible influence of prenatal stress and depression. J Assist Reprod Genet. 2019 Jul;36(7):1299-1313. doi: 10.1007/s10815-019-01483-0. Epub 2019 May 24. PMID: 31127477; PMCID: PMC6642239.
Kala M, Nivsarkar M. Role of cortisol and superoxide dismutase in psychological stress induced anovulation. Gen Comp Endocrinol. 2016 Jan 1;225:117-124. doi: 10.1016/j.ygcen.2015.09.010. Epub 2015 Sep 21. PMID: 26393311.
Gerogianni G, Babatsikou F, Polikandrioti M, Grapsa E. Management of anxiety and depression in haemodialysis patients: the role of non-pharmacological methods. Int Urol Nephrol. 2019 Jan;51(1):113-118. doi: 10.1007/s11255-018-2022-7. Epub 2018 Nov 19. PMID: 30456545.
Ramezanzade Tabriz E, Mohammadi R, Roshandel GR, Talebi R, Khorshidi M. Pain coping strategies and their relationship with unpleasant emotions (Anxiety, stress, and depression) and religious coping in cancer patients. Middle East Journal of Cancer. 2018;9(3):208-216. doi: 10.30476/mejc.2018.42125.
Niyazmand ZA, Abbasszadeh A, Borhani F, Sefidkar R. The relationship between spiritual health and hope in multiple sclerosis patients: A descriptive-correlational study. Electronic Journal of General Medicine. 2018;15(5). doi: 10.29333/ejgm/93464.
Raz DJ, Sun V, Kim JY, Williams AC, Koczywas M, Cristea M, Reckamp K, Hayter J, Tiep B, Ferrell B. Long-Term Effect of an Interdisciplinary Supportive Care Intervention for Lung Cancer Survivors After Surgical Procedures. Ann Thorac Surg. 2016 Feb;101(2):495-502; discussion 502-3. doi: 10.1016/j.athoracsur.2015.07.031. Epub 2015 Oct 9. PMID: 26443881; PMCID: PMC4718894.