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OCLC Number/Unique Identifier:

Kanemi Yusho and Transgenerational Epigenetic Inheritance

Biology Group    Start Submission

Tohru Shibuya* and Yukiharu Horiya

Dates: Received: 2023-03-15 | Accepted: 2023-03-28 | Published: 2023-03-30
Pages: 543-545


“Kanemi Yusho” was caused by the contamination of heated Polychlororinated Bisphenyls (PCBs) for deodorization in the manufacturing process of rice bran oil at the Kanemi Warehouse Co. Ltd., (Kokura-ward, Kitakyushu, Fukuoka, Japan) in 1968.People who ingested contaminated rice bran oil developed skin conditions, such as chloracne, which is characterized by black and white pustules, as well as liver and kidney diseases. A total of 15,000 peoples were affected. The sale of the contaminated rice bran oil was immediately banned, and it was concluded that the causative agent of “Kanemi Yusho” was Polychlorinated Dibenzofurans (PCDFs) derived from heated PCBs [1]. There toxicity are expressed after the activation by Aryl Hydrocarbon Receptor (AhR) [2].

FullText HTML FullText PDF DOI: 10.37871/jbres1708

Certificate of Publication


© 2023 Shibuya T, et al. Distributed under Creative Commons CC-BY 4.0

How to cite this article

Shibuya T, Horiya Y. Kanemi Yusho and Transgenerational Epigenetic Inheritance. 2023 Mar 30; 4(3): 543-545. doi: 10.37871/jbres1708, Article ID: JBRES1708, Available at:

Subject area(s)


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