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Phytochemistry and Biological-Pharmacological Profile of Aleurites moluccanus: A Critical Review

Biology Group    Start Submission

Siham Ayouaz*, Dwi LN Fibri, Radia Arab, Khokha Mouhoubi and Khodir Madani

Volume4-Issue2
Dates: Received: 2023-02-24 | Accepted: 2023-02-27 | Published: 2023-02-28
Pages: 310-316

Abstract

Background: Medicinal herbs are commonly used as fundamental ingredients in Asian countries. Our goal was to transcribe the ethno medicinal usage of Aleurites moluccanus and to highlight the stated pharmacological activity and composition.

Methods: Chemical composition and various pharmacological virtues of the different constituents of Aleurites moluccanus were obtained after an extensive survey from different scientific databases namely Elsevier, PubMed, Science Direct, Web of Science, Taylor and Francis, Google Scholar, Wiley On-line Library and ACS publications.

Results: Aleurites moluccanus are commonly used as a spice and flavoring element in cuisines, and their health advantages are well known. Perfumes contain them as well. Carbohydrates, proteins, minerals, lipids, essential oils, flavonoids, terpenoids, and carotenoids are among the chemical constituents of cardamom that have been identified through phytochemical investigations. Antioxidant, anti-diabetic, antibacterial, anticancer, gastroprotective, and insecticidal actions are only a few of the biological functions of the A. moluccanus. Further studies can be conducted to find out more about the pharmacological properties of the plant.

FullText HTML FullText PDF DOI: 10.37871/jbres1677


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Copyright

© 2023 Ayouaz S, et al. Distributed under Creative Commons CC-BY 4.0

How to cite this article

Ayouaz S, Fibri DLN, Arab R, Mouhoubi K, Madani K. Phytochemistry and Biological-Pharmacological Profi le of Aleurites moluccanus: A Critical Review. 2023 Feb 28; 4(2): 310-316. doi: 10.37871/jbres1677, Article ID: JBRES1677, Available at: https://www.jelsciences.com/articles/jbres1677.pdf


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References


  1. Lim TK. Aleurites moluccanus: Edible medicinal and non-medicinal plants. Fruits. 2012;2:465-471. doi: 10.1007/978-94-007-1764-0.
  2. Wang HB, Wang XY, Liu LP, Qin GW, Kang TG. Tigliane diterpenoids from the Euphorbiaceae and Thymelaeaceae families. Chem Rev. 2015 May 13;115(9):2975-3011. doi: 10.1021/cr200397n. Epub 2015 Apr 23. PMID: 25906056.
  3. Lincoln N, Zhang Q, Chen Q. State of the state tree: Historical and modern ecology of kukui (Candlenut, Aleurites moluccanus) in Hawai ‘i. Pacific Science. 2021;74(4):419-434. doi: 10.2984/74.4.9.
  4. Mistar EM, Sunatarty R, Zein I, Maulinda M, Amni C. Review potensi biomassa cangkang kemiri (Aleurites moluccana) sebagai bahan baku karbon aktif penyerap merkuri. Jurnal Serambi Engineering. 2023;8(1). doi: 10.32672/jse.v8i1.5551.
  5. de Britto Rosa MC, Ribeiro PR, de Oliveira Silva V, Selvati-Rezende DAC, da Silva TP, Souza FR, Cardoso MDG, Seixas JN, Andrade EF, Pardi V, Murata RM, Pereira LJ. Fatty acids composition and in vivo biochemical effects of Aleurites moluccana seed (Candlenut) in obese wistar rats. Diabetol Metab Syndr. 2022 Jun 8;14(1):80. doi: 10.1186/s13098-022-00847-4. PMID: 35676689; PMCID: PMC9178887.
  6. Juwono H, Dewi A, Nilasari G, Harmami, Widjaja T, Altway A, Bachtiar A, Ni’mah Y. Alternative liquid fuel from catalytic cracking of candlenut oil biodiesel (Aleurites moluccana) and PP/PS plastic waste. Journal of Hunan University Natural Sciences. 2022;49(1).
  7. Adnan J, Dalming T, Setiawan R. Pengaruh konsentrasi virgin coconut oil dan minyak kemiri (Aleurites moluccanus (l.) willd) terhadap mutu fisik formula pomade rambut. Journal Pharmacy of Pelamonia. 2022;2(1):27-36.
  8. Surbakti MPB, Sebayang F. Calcium silicate as a media for enhancement of Vitamin E concentration from candlenut oil (Aleurites moluccana). Journal of Chemical Natural Resources. 2022;4(1):33-43.
  9. Tillman H, Gassmann J, Stensgard S, Nguyen A, Tieu N, Melbardis M, Gharibyar H. Pharmacist’s evaluation of natural ingredients in topical products for rheumatoid arthritis. Pharmacology & Pharmacy. 2022;13(8):273-284. doi: 10.4236/pp.2022.138021.
  10. Muliani S. modifikasi permukaan karbon aktif dari tempurung kemiri (Aleurites moluccana) dengan HNO3 dan aplikasinya sebagai adsorben zat warna metil jingga surface modification of activated carbon from candlenut shell (Aleurites moluccana) with HNO3 and its application as an adsorbent methyl orange dyes. Universitas Hasanuddin. 2022.
  11. Cahya CAD, Lubis DFY. Workshop of formulation on preparation gel (Aleurites moluccana) as anticeptic hand sanitizer against bacteria Staphylococcus aureus. Jurnal Pengmas Kestra. 2022;2(2):153-157. doi: 10.35451/jpk.v2i2.1431.
  12. Kibazohi O, Sangwan RS. Vegetable oil production potential from Jatropha curcas, Croton megalocarpus, Aleurites moluccana, Moringa oleifera and Pachira glabra: Assessment of renewable energy resources for bio-energy production in Africa. Biomass and Bioenergy. 2011;35(3):1352-1356. doi: 10.1016/j.biombioe.2010.12.048.
  13. Chasanah UF, Yudastama F, Rahmasari D. Characteristics and stability of candle nut oil (Aleurites moluccana) nanoemulsion hair tonic preparation. KnE Medicine. 2022;576-585. doi: 10.18502/kme.v2i3.11911.
  14. Krisnawati H, Kallio M, Kanninen M. Aleurites moluccana (L.) Willd: Ecology, silviculture and productivity. CIFOR. 2011.
  15. Meyre-Silva C, Mora TC, Biavatti MW, Santos ARS, Dal-Margo J, Yunes RA, Cechinel-Filho V. Preliminary phytochemical and pharmacological studies of Aleurites moluccana leaves [L.] Willd. Phytomedicine. 1998;5(2):109-113. doi: 10.1016/S0944-7113(98)80006-8.
  16. Larrue S, Meyer JY, Chiron T. Anthropogenic vegetation contributions to Polynesia’s social heritage: The legacy of candlenut tree (Aleurites moluccana) forests and bamboo (Schizostachyum glaucifolium) groves on the island of Tahiti. Economic Botany. 2010;64(4):329-339.
  17. Leke JR, Sompie F, Bagau B, Podung A, Sarajar C, Siahaan R, Pudjihastuti E, Widodo E. The effect of candlenut (Aleurites moluccana I Willd.) seed flour in native chicken feeding toward the internal egg quality and cholesterol contens. Jurnal Ilmu dan Teknologi Hasil Ternak. 2022;17(2):64-73. doi: 10.21776/ub.jitek.2022.017.02.1.
  18. Keller HA, Stampella P, Delucchi G, Hurrell JA. Vernicia fordii y Aleurites moluccanus (Euphorbiaceae) en la Argentina. Naturalización y etnobotánica. Boletín de la Sociedad Argentina de Botánica. 2013;48(3-4):553-561. doi: 10.31055/1851.2372.v48.n3-4.7609.
  19. Liu HY, Li SJ, Zhao Y, Ni W, Hao XJ, Li JZ, Hua Y, Xie BB, Qing C, Chen CX. Four new podocarpane‐type trinorditerpenes from Aleurites moluccana. Helvetica Chimica Acta. 2007;90(10):2017-2023. doi: 10.1002/hlca.200790209.
  20. Alimboyoguen AB, De Castro-Cruz KA, Shen CC, Li WT. Chemical constituents of the bark of Aleurites moluccana L. Willd. Journal of Chemical & Pharmaceutical Research. 2014;6(5):1318-1320.
  21. Cabral MRP, dos Santos SAL, Stropa JM, de L. da Silva RC, Cardoso CAL, de Oliveira LCS, Scharf DR, Simionatto EL, Santiago EF, Simionatto E. Chemical composition and thermal properties of methyl and ethyl esters prepared from Aleurites moluccanus (L.) Willd (Euphorbiaceae) nut oil. Industrial Crops and Products. 2016;85:109-116. doi: 10.1016/j.indcrop.2016.02.058.
  22. Quintão NL, Meyre-Silva C, Silva GF, Antonialli CS, Rocha LW, Lucinda-Silva RM, Malheiros A, Souza MM, Cechinel Filho V, Bresolin TM. Aleurites moluccana (L.) Willd. Leaves: Mechanical Antinociceptive Properties of a Standardized Dried Extract and Its Chemical Markers. Evid Based Complement Alternat Med. 2011;2011:179890. doi: 10.1155/2011/179890. Epub 2011 Mar 23. PMID: 21660087; PMCID: PMC3092167.
  23. de Britto Rosa MC, Ribeiro PR, de Oliveira Silva V, Selvati-Rezende DAC, da Silva TP, Souza FR, Cardoso MDG, Seixas JN, Andrade EF, Pardi V, Murata RM, Pereira LJ. Fatty acids composition and in vivo biochemical effects of Aleurites moluccana seed (Candlenut) in obese wistar rats. Diabetol Metab Syndr. 2022 Jun 8;14(1):80. doi: 10.1186/s13098-022-00847-4. PMID: 35676689; PMCID: PMC9178887.
  24. Almas JF, Chasanah U, Rahmasari D. Activity of hair tonic nanoemulsion with candlenut oil (Aleurites moluccana) on mice (Mus musculus). KnE Medicine. 2022;630-636.
  25. Ariesto MR. Efek pemberian minyak kemiri (Aleurites moluccana L.) Dosis bertingkat terhadap gambaran histopatologi gaster tikus model gastritis yang diinduksi aspirin. Universitas Jenderal Soedirman. 2023.
  26. Liu H, Di Y, Yang J, Teng F, Lu Y, Ni W, Chen C, Hao X. Three novel 3, 4-seco-podocarpane trinorditerpenoids from Aleurites moluccana. Tetrahedron Letters. 2008;49(35):5150-5151. doi: 10.1016/j.tetlet.2008.06.088.
  27. Meyre-Silva C, Mora TC, Santos ARS, Magro JD, Yunes R, Monache F, Cechinel-Filho V. A Triterpene and a flavonoid glycoside from Aleurites moluccana L. Willd (Euphorbiaceae). Acta Farmaceutica Bonaerense. 1997;16:169-172.
  28. Prabowo WC, Wirasutisna KR, Insanu M. Isolation and characterization of 3-acetyl aleuritolic acid and scopoletin from stem bark of Aleurites moluccana (L.) Willd. Int J Pharm Pharm Sci. 2013;5(3):851-853.
  29. Satyanarayana P, Kumar KA, Singh SK, Rao GN. A new phorbol diester from Aleurites moluccana. Fitoterapia. 2001 Mar;72(3):304-6. doi: 10.1016/s0367-326x(00)00314-2. PMID: 11295313.
  30. Sotheeswaran S, Sharif MR, Moreau RA, Piazza GJ. Lipids from the seeds of seven Fijian plant species. Food Chemistry. 1994;49(1):11-13. doi: 10.1016/0308-8146(94)90225-9.
  31. Girardi LG, Morsch M, Cechinel-Filho V, Meyre-Silva C, Rodrigues CA. Isolation of flavonoids from Aleurites moluccana using chitosan modified with benzaldehyde (CH-Bz) as chromatographic support. Pharmazie. 2003 Sep;58(9):629-30. PMID: 14531457.
  32. Quintão NL, Rocha LW, Silva GF, Reichert S, Claudino VD, Lucinda-Silva RM, Malheiros A, De Souza MM, Cechinel Filho V, Bellé Bresolin TM, da Silva Machado M, Wagner TM, Meyre-Silva C. Contribution of α,β-Amyrenone to the Anti-Inflammatory and Antihypersensitivity Effects of Aleurites moluccana (L.) Willd. Biomed Res Int. 2014;2014:636839. doi: 10.1155/2014/636839. Epub 2014 Oct 19. PMID: 25386561; PMCID: PMC4217248.
  33. de Souza MM, Chagas LGRD, Gonçalves AE, Tomczak M, Reichert S, Schuquel ITA, Cechinel-Filho V, Meyre-Silva C. Phytochemical Analysis and Antinociceptive Properties of Hydroalcoholic Extracts of Aleurites moluccanus Bark. Planta Med. 2021 Aug;87(10-11):896-906. doi: 10.1055/a-1497-0239. Epub 2021 May 25. PMID: 34034350.
  34. Meyre-Silva C, Yunes RA, Santos AR, Magro JD, Delle-Monache F, Cechinel-Filho V. Isolation of a C-Glycoside Flavonoid with Antinociceptive Action from Aleurites moluccana Leaves. Planta Med. 1999 Apr;65(3):293-4. doi: 10.1055/s-2006-960785. PMID: 17260309.
  35. Cesca TG, Faqueti LG, Rocha LW, Meira NA, Meyre-Silva C, de Souza MM, Quintão NL, Silva RM, Filho VC, Bresolin TM. Antinociceptive, anti-inflammatory and wound healing features in animal models treated with a semisolid herbal medicine based on Aleurites moluccana L. Willd. Euforbiaceae standardized leaf extract: semisolid herbal. J Ethnopharmacol. 2012 Aug 30;143(1):355-62. doi: 10.1016/j.jep.2012.06.051. Epub 2012 Jul 7. PMID: 22776834.
  36. Pedrosa RC, Meyre-Silva C, Cechinel-Filho V, Benassi JC, Oliveira LF, Zancanaro V, Dal Magro J, Yunes RA. Hypolipidaemic activity of methanol extract of Aleurites moluccana. Phytother Res. 2002 Dec;16(8):765-8. doi: 10.1002/ptr.1046. PMID: 12458484.
  37. Hakim A, Jamaluddin J, Al Idrus SW, Jufri AW, Ningsih BNS. Ethnopharmacology, phytochemistry, and biological activity review of Aleurites moluccana. Journal of Applied Pharmaceutical Science. 2022;12(4):170-178. doi: 10.7324/JAPS.2022.120419.
  38. Niazi J, Gupta V, Chakarborty P, Kumar P. Antiinflammatory and antipyretic activity of Aleuritis moluccana leaves. Asian J Pharm Clin Res. 2010;3(1):35-37.
  39. Mendes Hoepers S, Tolentino de Souza HG, Meira Quintão NL, Roberto Santin J, Cechinel Filho V, Silva RM, Garcia Couto A, Simão da Silva KA. Topical anti-inflammatory activity of semisolid containing standardized Aleurites moluccana L. Willd (Euphorbiaceae) leaves extract. J Ethnopharmacol. 2015 Sep 15;173:251-5. doi: 10.1016/j.jep.2015.07.024. Epub 2015 Jul 18. PMID: 26196401.
  40. Mac Donald R, Camargo SS, Meyre-Silva C, Quintão NLM, Filho VC, Bresolin TMB, Lucinda-Silva RM. Development of an oral suspension containing dry extract of Aleurites moluccanus with anti-inflammatory activity. Revista Brasileira de Farmacognosia. 2016;26:68-76. doi: 10.1016/j.bjp.2015.06.011.
  41. Ubeda LCC, Araújo AC, Barbalho SM, dos Santos Bueno PC, Guiguer EL, de Sousa MDSS, Dias FDA, Modesto AN, Pinheiro RA, Marutani VH, Prando M. Effects of the seeds of Aleurites moluccana on the metabolic profile of wistar rats. The Pharma Innovation. 2017;6(1):98-103.
  42. Perera HDSM, Samarasekera JKRR, Handunnetti SM, Weerasena OVDSJ. In vitro anti-inflammatory and anti-oxidant activities of Sri Lankan medicinal plants. Industrial Crops and Products. 2016;94:610-620. doi: 10.1016/j.indcrop.2016.09.009.


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