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Effect of Fastigial Nucleus Stimulation on Serum Inflammatory Factors in Patients with Coronary Heart Disease

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Open Access
Article Type Research Article
Subject Medicine Group
OCLC JBRES Record
Li Wensong, Zhou Zicheng and Zhang Runfeng*
Issue: Volume3-Issue10
Pages: 1240-1243
Received: 2022-10-15
Accepted: 2022-10-25
Published: 2022-10-26

Abstract

Objective: To observe the effect of Fastigial Nucleus Stimulation (FNS) on serum inflammatory factors in patients with coronary heart disease.

Methods: 144 patients with coronary heart disease were randomly divided into the experimental group (n = 72) and the control group (n = 72). The control group received conventional medication for coronary heart disease. The experimental group was given the cerebellar nucleus electrical stimulation on the basis of routine medication. High-sensitivity C-reactive protein (hs-CRP), Interleukin-6 (IL-6), Tumor Necrosis Factor α (TNF-α), Lipoprotein-associated phospholipase A2 (Lp-PLA2) were measured before and after treatment in both groups.

Results: There were no significant differences in serum hs-CRP, TNF-α, IL-6 and Lp-PLA2 between the two groups before treatment (p > 0.05). After treatment, serum hs-CRP, TNF-α, IL-6 and Lp-PLA2 were significantly lower in the two groups than before treatment (p < 0.01). The levels of serum hs-CRP, TNF- α , IL-6 and Lp-PLA2 in the experimental group were significantly lower than those in the control group (p < 0.05).

Conclusion: FNS can effectively reduce the level of serum inflammatory factors in patients with coronary heart disease. (Clinical Trial Registration: URL: http://www.clinicaltrials.gov. Unique identifier: NCT04121715).

FullText HTML FullText PDF DOI: 10.37871/jbres1584 Crossmark

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© 2022 Wensong L, et al. Distributed under Creative Commons CC-BY 4.0 Creative CommonsAttribution

How to cite this article

Wensong L, Zicheng Z, Runfeng Z. Effect of Fastigial Nucleus Stimulation on Serum Inflammatory Factors in Patients with Coronary Heart Disease. 2022 Oct 26; 3(10): 1240-1243. doi: 10.37871/jbres1584, Article ID: JBRES1584, Available at: https://www.jelsciences.com/articles/jbres1584.pdf

Subject area(s)

Vascular MedicineCardiovascular DiseasesClinical Cardiology

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