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Case Report

Three Haemoglobin Variants for Congenital Erythrocytosis and Sickle Cell Disease HbSC

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Open Access
Article Type Case Report
Subject Medicine Group
OCLC JBRES Record
Epifania Rita Testa*, Luciana Geremia, Valeria Brunetta, Roberto Tassan-Toffola, Pietro Polito, Rosalinda Testa, Lara Bet, Katia Piccinin, Mara Simonella, Paola Pupulin1 and Andrea Bontadini
Issue: Volume3-Issue10
Pages: 1204-1207
Received: 2022-09-29
Accepted: 2022-10-20
Published: 2022-10-18

Abstract

The inherited haemoglobin disorders and the clinical laboratory is essential in the diagnosis. Phlebotomy is the therapeutic procedure indicated to reduce blood viscosity and decreasing the risk of thrombotic events in the haemoglobin variants with high affinity for O2 or vaso-occlusive crises in Sickle Cell Disease (SCD) with double heterozygosity HbSC. We describe how therapeutic bleeding remains the treatment in two variant haemoglobinopathies, Haemoglobin Regina and the Haemoglobin Trollhattan, reported for the first time in the Italian population and a double heterozygosity HbSC. In patients with high haematocrit level when other secondary conditions of polyglobulia are excluded, a High-Performance Liquid Chromatography (HPLC) analysis for haemoglobin study should be suggested. Also in children with erythrocytosis frequently, such as the finding of Haemoglobin Okazaky.

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Copyright

© 2022 Testa ER, et al.. Distributed under Creative Commons CC-BY 4.0 Creative CommonsAttribution

How to cite this article

Testa ER, Geremia L, Brunetta V, Tassan-Toffola R, Polito P, Testa R, Bet L, Piccinin K, Simonella M, Pupulin P, Bontadini A. Shedding Light on Child Physical Abuse and its Ramifications: A Review. 2022 Oct 18; 3(10): 1204-1207. doi: 10.37871/jbres1579, Article ID: JBRES1579, Available at: https://www.jelsciences.com/articles/jbres1579.pdf

Subject area(s)

HematologyBlood Disorders

References

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