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The Relationship between Intakes of Iron, Folic Acid, Vitamin C, Age at Menarche, Hemoglobin Status and Physical Activity with Menstrual Cycles in Female Students at Smait Al-Ichwan Cikarang Utara-Indonesia

Medicine Group    Start Submission

Isma Nurhalisa and Moesijanti YE Soekatri*

Dates: Received: 2022-06-17 | Accepted: 2022-06-25 | Published: 2022-06-30
Pages: 742-747


Background: Adolescence is the period of transition from children becoming adults that is marked by the occurrence of puberty, namely menstruation. At that time there was a change in the reproductive system that allows the occurrence of disturbances, one of which is menstrual cycle disorders.

Aim: Based on data from RISKESDAS (basic health survei) (2013), it shows that the percentage of menstrual cycle irregularities at the age of 10-29 years is 16.4% (RISKESDAS (basic health survei). Irregular menstrual cycles in adolescent girls aged 15-19 years are 11.7% and as many as 14.9% women who live in urban areas in Indonesia.

Methods: Samples were taken by using purposive sampling technique; it is obtained a sample of 35 students from grade 11 and 12 aged 16-18 years at SMAIT-Al-Ichwan Cikarang Utara. Data on the age at menarche and menstrual cycle with the method of interview used a questionnaire, food intake was obtained from 2x24 hours food recall form that is not in a row and hemoglobin status used Easy Touch Blood Hb tool conducted by nurses. Physical activity data was obtained by filling out a form and the results were calculated by using the PAR/PAL method. Statistical analysis used a chi-square test and used a fisher exact test value.

Results: The results of the reserach showed that there is no significant relationship between the intake of iron, folic acid, vitamin C and physical activity on menstrual cycle (p > 0.05).

Conclusion: This conclusion constitues there is a significant relationship between hemoglobin status on menstrual cycle (p = 0.005).

FullText HTML FullText PDF DOI: 10.37871/jbres1508

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© 2022 Nurhalisa I, et al. Distributed under Creative Commons CC-BY 4.0

How to cite this article

Nurhalisa I, Soekatri MYE. The Relationship between Intakes of Iron, Folic Acid, Vitamin C, Age at Menarche, Hemoglobin Status and Physical Activity with Menstrual Cycles in Female Students at Smait Al-Ichwan Cikarang Utara-Indonesia. J Biomed Res Environ Sci. 2022 June 30; 3(6): 742-747. doi: 10.37871/jbres1508, Article ID: JBRES1508, Available at:

Subject area(s)


  1. Proverawati A, Misaroh S. Menarche meaningful first menstruation. 2009.
  2. Research and Development Agency. Basic health survey. 2013.
  3. Azizah H. Relationship between age at menarche, physical activity and nutrition knowledge with menstrual cycle in adolescent girls. 2020.
  4. Basic Health Survey. Health Survey and Development Agency. Indonesian Ministry of Health. Jakarta. 2010.
  5. Wahab A, Wilopo SA, Hakimi M, Ismail D. Declining age at menarche in Indonesia: A systematic review and meta-analysis. Int J Adolesc Med Health. 2018 Sep 26;32(6). Doi: 10.1515/ijamh-2018-0021. PMID: 30256760.
  6. Atarod Z, Alami S, Bahari M, Hashemi, Kianejad A. Prevalence of menstrual disorders and associated risk factors in high school female students in pulo gadung district, east Jakarta. Medical Journal of Indonesia. 2009;59(7):308-313.
  7. Handayani MS, Dwiriani CM, Riyadi H. Relationship between body composition and nutritional status with sexual development. J Nutrition and Food. 2013.
  8. Heriyanto MH. Relationship between nutritional intake and other factors with body fat percentage in female students of nutrition and communication studies at UI class of 2009 and 2012. University of Indonesia. 2012.
  9. Yermachenko A, Dvornyk V. Nongenetic determinants of age at menarche: A systematic review. Biomed Res Int. 2014;2014:371583. doi: 10.1155/2014/371583. Epub 2014 Jun 23. PMID: 25050345; PMCID: PMC4094877.
  10. Ministry of Health. Basic health survey, Jakarta: Health survey and development agency, ministry of health RI. 2013.
  11. Adelia D. Prediction of haemoglobin levels based on intake of protein, iron, vitamin c, vitamin a, menstrual patterns and knowledge of nutrition in female students, south Jakarta. Polytechnic of Health Ministry of Health Jakarta II. 2015.
  12. Wiranti AA. Relationship between intake of micro nutrients (iron, vitamin B12, and vitamin A) with the incidence of anaemia in female students. Scientific Works. 2016;8–13.
  13. Wahyuningsih M. Relationship between nutrient intake, physical activity, and nutritional status on menstrual cycle of adolescent girls. Polytechnic of Health Ministry of Health Jakarta II. 2020.
  14. Adillah A. The influence of counselling about iron nutritional anaemia using online puzzle media on the level of knowledge. 2019:16-17.
  15. Restuti AN, Susindra Y. Relationship between nutrient intake and nutritional status with the incidence of anemia in adolescent girls. Seminar. Results Study and Devotion. 2016:78.
  16. Wahyuni Y, Dewi R. Menstrual cycle disorders related to nutrient intake in vegetarian adolescents. 2018.
  17. Maulani, Annisa. Relationship between nutritional status, micronutrient intake and stress level with menstrual cycle in female nutrition students of Uhamka. Jakarta: Proceedings of the national seminar on strengthening research and its outcomes as academic culture in higher education. 2019.
  18. Catrine F, Nazhif G, Erry YM, Rachmanida N, Putri R. Relationship between intake, nutritional status, physical activity, stress level and menstrual cycle of badminton athletes. Nutrition Studies Program. 2021.
  19. Krisna A, Prastiwi I, Iskandar M, Kebidanan A, Cikarang BH. Factors related to the menstrual cycle in adolescent girls in class XI at SMAN 3 Cikarang Utara Regency. 2019.
  20. Rakhmawati A. The relationship between obesity and the incidence of menstrual cycle disorders in young adult women. Semarang: Diponegoro University. 2012.
  21. Wahyuni, Dewi, Ratna. Menstrual cycle disorders related to nutritional intake in vegetarian teens. Jakarta: Indonesian Journal of Nutrition. 2018.
  22. Epri Sugma. Article review of the effect of stress on menstrual cycle in adolescent. Lampung: Lampung University. 2015.
  23. Kritianti Septi. Relationship between anaemia and menstrual cycle in adolescent girls. Journal of Youth Studies. 2013.
  24. Bilkisthi, Sabilla. Relationship between menstrual cycle, amount of blood that comes out during menstruation, nutritional adequacy and nutritional status, and the effect of blood supplementation (TTD) with anaemia status in adolescent girls at the Minhaajurrosyidiin Islamic boarding school jakarta. Nutritiont Department, Polytechnic of Health Ministry of Health Jakarta II. 2017.
  25. Mariatus, Sholihah D. The correlation between exercise activity, genetic background, fast-food consumption, and dysmenorrhea. Periodic Epidemiology Journal. 2019.
  26. Anindita, Darwin, Afriwardi. The relationship between daily physical activity and menstrual disorders in medical college students at Andalas University. Andalas Journal of Health. 2016.
  27. Mahitala, Anindita. Relationship between physical activity and menstrual disorders in women of fertility age in Temanggung village, Kaliangkrik district, Magelang regency in 2015. Journal of Public Health. 2017;3(3):74-80.


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