Covid-19 Research

Case Report

OCLC Number/Unique Identifier: 9575234757

An Infant with Hydrocephalus and Hepatomegaly

Medicine Group    Start Submission

Patricia Pichilingue-Reto*, Lara Pavageau, Venkat Kakkilaya, Naseem Uddin and Amanda S Evans

Volume3-Issue6
Dates: Received: 2022-06-21 | Accepted: 2022-06-27 | Published: 2022-06-29
Pages: 722-725

Abstract

We report a histologic and PCR-confirmed case of symptomatic congenital toxoplasmosis in a premature infant with optic nerve atrophy and severe ventriculomegaly requiring ventriculoperitoneal shunt in the absence of cerebral calcifications. A significant risk factor in acquisition of this congenital infection was mother’s consumption of raw deer meat during pregnancy.

FullText HTML FullText PDF DOI: 10.37871/jbres1503


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Copyright

© 2022 Pichilingue-Reto P, et al. Distributed under Creative Commons CC-BY 4.0

How to cite this article

Pichilingue-Reto P, Pavageau L, Kakkilaya V, Uddin N, Evans AS. An Infant with Hydrocephalus and Hepatomegaly. J Biomed Res Environ Sci. 2022 June 29; 3(6): 722-725. doi: 10.37871/jbres1503, Article ID: JBRES1503, Available at: https://www.jelsciences.com/articles/jbres1503.pdf


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References


  1. Pappas G, Roussos N, Falagas ME. Toxoplasmosis snapshots: global status of Toxoplasma gondii seroprevalence and implications for pregnancy and congenital toxoplasmosis. Int J Parasitol. 2009 Oct;39(12):1385-94. doi: 10.1016/j.ijpara.2009.04.003. Epub 2009 May 9. PMID: 19433092.
  2. Jones JL, Kruszon-Moran D, Elder S, Rivera HN, Press C, Montoya JG, McQuillan GM. Toxoplasma gondii Infection in the United States, 2011-2014. Am J Trop Med Hyg. 2018 Feb;98(2):551-557. doi: 10.4269/ajtmh.17-0677. Epub 2017 Dec 14. Erratum in: Am J Trop Med Hyg. 2018 Jul;99(1):241-242. PMID: 29260660; PMCID: PMC5929212.
  3. Owusu-Dommey A, Pogreba-Brown K, Villa-Zapata L. Seroprevalence of Toxoplasma gondii in the U.S.: Evidence from a representative cross-sectional survey. Parasitol Int. 2020 Dec;79:102175. doi: 10.1016/j.parint.2020.102175. Epub 2020 Aug 5. PMID: 32763362.
  4. Maldonado YA, Read JS; COMMITTEE ON INFECTIOUS DISEASES. Diagnosis, Treatment, and Prevention of Congenital Toxoplasmosis in the United States. Pediatrics. 2017 Feb;139(2):e20163860. doi: 10.1542/peds.2016-3860. PMID: 28138010.
  5. Brady-McCreery KM, Hussein MA, Paysse EA. Congenital toxoplasmosis with unusual retinal findings. Arch Ophthalmol. 2003 Aug;121(8):1200-1. doi: 10.1001/archopht.121.8.1200. PMID: 12912703.
  6. Jones JL, Dargelas V, Roberts J, Press C, Remington JS, Montoya JG. Risk factors for Toxoplasma gondii infection in the United States. Clin Infect Dis. 2009 Sep 15;49(6):878-84. doi: 10.1086/605433. PMID: 19663709.
  7. Gerhold RW, Saraf P, Chapman A, Zou X, Hickling G, Stiver WH, Houston A, Souza M, Su C. Toxoplasma gondii seroprevalence and genotype diversity in select wildlife species from the southeastern United States. Parasit Vectors. 2017 Oct 23;10(1):508. doi: 10.1186/s13071-017-2456-2. PMID: 29061166; PMCID: PMC5654087.
  8. Gaulin C, Ramsay D, Thivierge K, Tataryn J, Courville A, Martin C, Cunningham P, Désilets J, Morin D, Dion R. Acute Toxoplasmosis among Canadian Deer Hunters Associated with Consumption of Undercooked Deer Meat Hunted in the United States. Emerg Infect Dis. 2020 Feb;26(2):199-205. doi: 10.3201/eid2602.191218. PMID: 31961291; PMCID: PMC6986818.
  9. Contopoulos-Ioannidis D, Wheeler KM, Ramirez R, Press C, Mui E, Zhou Y, Van Tubbergen C, Prasad S, Maldonado Y, Withers S, Boyer KM, Noble AG, Rabiah P, Swisher CN, Heydemann P, Wroblewski K, Karrison T, Grigg ME, Montoya JG, McLeod R. Clustering of Toxoplasma gondii Infections Within Families of Congenitally Infected Infants. Clin Infect Dis. 2015 Dec 15;61(12):1815-24. doi: 10.1093/cid/civ721. Epub 2015 Sep 24. PMID: 26405150; PMCID: PMC4657536.
  10. Olariu TR, Remington JS, McLeod R, Alam A, Montoya JG. Severe congenital toxoplasmosis in the United States: clinical and serologic findings in untreated infants. Pediatr Infect Dis J. 2011 Dec;30(12):1056-61. doi: 10.1097/INF.0b013e3182343096. PMID: 21956696.
  11. McAuley JB. Congenital Toxoplasmosis. J Pediatric Infect Dis Soc. 2014 Sep;3 Suppl 1(Suppl 1):S30-5. doi: 10.1093/jpids/piu077. PMID: 25232475; PMCID: PMC4164182.
  12. Olariu TR, Press C, Talucod J, Olson K, Montoya JG. Congenital toxoplasmosis in the United States: clinical and serologic findings in infants born to mothers treated during pregnancy. Parasite. 2019;26:13. doi: 10.1051/parasite/2019013. Epub 2019 Mar 6. PMID: 30838974; PMCID: PMC6402364.
  13. Hutson SL, Wheeler KM, McLone D, Frim D, Penn R, Swisher CN, Heydemann PT, Boyer KM, Noble AG, Rabiah P, Withers S, Montoya JG, Wroblewski K, Karrison T, Grigg ME, McLeod R. Patterns of Hydrocephalus Caused by Congenital Toxoplasma gondii Infection Associate With Parasite Genetics. Clin Infect Dis. 2015 Dec 15;61(12):1831-4. doi: 10.1093/cid/civ720. Epub 2015 Sep 24. PMID: 26405147; PMCID: PMC4657535.
  14. Khan K, Khan W. Congenital toxoplasmosis: An overview of the neurological and ocular manifestations. Parasitol Int. 2018 Dec;67(6):715-721. doi: 10.1016/j.parint.2018.07.004. Epub 2018 Jul 21. PMID: 30041005.
  15. Popli MB, Popli V. Neuroimage: Congenital toxoplasmosis. Neurol India. 1999 Mar;47(1):74. PMID: 10339716.
  16. Remington JS, McLeod R, Wilson CB, Desmonts G. Toxoplasmosis. In: Remington JS, Klein JO, Wilson, Victor Nizet, Maldonado YA, editors. Infectious diseases of the fetus and newborn. 7th ed. Saunders WB; 2011. p.918-1041. doi: 10.1016/B978-1-4160-6400-8.00031-6.
  17. Patel DV, Holfels EM, Vogel NP, Boyer KM, Mets MB, Swisher CN, Roizen NJ, Stein LK, Stein MA, Hopkins J, Withers SE, Mack DG, Luciano RA, Meier P, Remington JS, McLeod RL. Resolution of intracranial calcifications in infants with treated congenital toxoplasmosis. Radiology. 1996 May;199(2):433-40. doi: 10.1148/radiology.199.2.8668790. PMID: 8668790.
  18. Robert-Gangneux F, Dupretz P, Yvenou C, Quinio D, Poulain P, Guiguen C, Gangneux JP. Clinical relevance of placenta examination for the diagnosis of congenital toxoplasmosis. Pediatr Infect Dis J. 2010 Jan;29(1):33-8. doi: 10.1097/INF.0b013e3181b20ed1. PMID: 19858771.
  19. Toxoplasma gondii Infections. In: Kimberlin DW, Brady MT, Jackson MA, Long SS, editors. Red Book: 2018 Report of the Committee on Infectious Diseases. American Academy of Pediatrics; 2018. p.809-819.


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