Covid-19 Research

Review Article

OCLC Number/Unique Identifier: 9575255467

Prevalence of Depression and Academic Performance among Medical Students: A Systematic Review

Medicine Group    Start Submission

Nkporbu AK* and Ayodeji O

Volume3-Issue6
Dates: Received: 2022-06-03 | Accepted: 2022-06-27 | Published: 2022-06-28
Pages: 714-721

Abstract

Background: Depression is the single largest contributor to global disability and disease burden. Medical students are considered a vulnerable group because they have to deal with stressors specific to medical education. Psychological morbidity in medical students represents a neglected public health problem and holds major implications for health services and mental health policymaking.

Aim: To ascertain the prevalence of depression and its impact on academic performance among medical students.

Design: A systematic review

Data sources: Systematic search for worldwide published literature from PubMed, PsycINFO, EMBASE, Google Scholar, EMBASE, Science Direct, BioMed Central and Medline databases

Study eligibility criteria: Studies included in this review reported the methods and/or measures for the prevalence of depression and academic performance among medical students

Data extraction: Data extraction was undertaken by the first reviewer, and checked by a second reviewer. All identified papers were critically appraised independently by both reviewers. Information was extracted from each included study (including author, title, year and setting of study). These data abstraction forms were reviewed and eligible papers entered into the meta-analysis.

Result: Out of a total of 2,236 publications retrieved, after examining the titles, abstracts (if abstract was unavailable, the article was nevertheless counted) and the reference lists for related articles, only 14 studies satisfied all the inclusion criteria. Non-English articles (French 1, Japanese 1, Mexican 1, Korean 2) were excluded to save time and cost.

Conclusion:
Moderate and severe depression showed a high prevalence among medical students. The presence mental health services for university students and medical students in particular is important. Efforts of professors in charge of preparing the exams should be directed towards making the oral and clinical exams more transparent.

FullText HTML FullText PDF DOI: 10.37871/jbres1502


Certificate of Publication




Copyright

© 2022 Nkporbu AK, et al. Distributed under Creative Commons CC-BY 4.0

How to cite this article

Nkporbu AK, Ayodeji O. Prevalence of Depression and Academic Performance among Medical Students: A Systematic Review. J Biomed Res Environ Sci. 2022 June 28; 3(6): 714-721. doi: 10.37871/jbres1502, Article ID: JBRES1502, Available at: https://www.jelsciences.com/articles/jbres1502.pdf


Subject area(s)

References


  1. Depression and other common mental disorders: Global health estimates. Division of Mental Health. World Health Organization. 2017.
  2. GBD 2015 Disease and Injury Incidence and Prevalence Collaborators. Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015. Lancet. 2016 Oct 8;388(10053):1545-1602. doi: 10.1016/S0140-6736(16)31678-6. Erratum in: Lancet. 2017 Jan 7;389(10064):e1. PMID: 27733282; PMCID: PMC5055577.
  3. Battle DE. Diagnostic and Statistical Manual of Mental Disorders (DSM). Codas. 2013;25(2):191-2. doi: 10.1590/s2317-17822013000200017. PMID: 24413388.
  4. Lei XY, Xiao LM, Liu YN, Li YM. Prevalence of Depression among Chinese University Students: A Meta-Analysis. PLoS One. 2016 Apr 12;11(4):e0153454. doi: 10.1371/journal.pone.0153454. PMID: 27070790; PMCID: PMC4829172.
  5. Hysenbegasi A, Hass SL, Rowland CR. The impact of depression on the academic productivity of university students. J Ment Health Policy Econ. 2005 Sep;8(3):145-51. PMID: 16278502.
  6. Yalemwork G. Depression among addis ababa university students sidist kilo campus: Prevalence, gender difference and other associated factors. 2015.
  7. Rotenstein LS, Ramos MA, Torre M, Segal JB, Peluso MJ, Guille C, Sen S, Mata DA. Prevalence of Depression, Depressive Symptoms, and Suicidal Ideation Among Medical Students: A Systematic Review and Meta-Analysis. JAMA. 2016 Dec 6;316(21):2214-2236. doi: 10.1001/jama.2016.17324. PMID: 27923088; PMCID: PMC5613659.
  8. Puthran R, Zhang MW, Tam WW, Ho RC. Prevalence of depression amongst medical students: a meta-analysis. Med Educ. 2016 Apr;50(4):456-68. doi: 10.1111/medu.12962. PMID: 26995484.
  9. Dyrbye LN, Thomas MR, Shanafelt TD. Systematic review of depression, anxiety, and other indicators of psychological distress among U.S. and Canadian medical students. Acad Med. 2006 Apr;81(4):354-73. doi: 10.1097/00001888-200604000-00009. PMID: 16565188.
  10. Ngasa SN, Sama CB, Dzekem BS, Nforchu KN, Tindong M, Aroke D, Dimala CA. Prevalence and factors associated with depression among medical students in Cameroon: a cross-sectional study. BMC Psychiatry. 2017 Jun 9;17(1):216. doi: 10.1186/s12888-017-1382-3. PMID: 28599624; PMCID: PMC5466797.
  11. Aniebue PN, Onyema GO. Prevalence of depressive symptoms among Nigerian medical undergraduates. Trop Doct. 2008 Jul;38(3):157-8. doi: 10.1258/td.2007.070202. PMID: 18628542.
  12. Basnet B, Jaiswal M, Adhikari B, Shyangwa PM. Depression among undergraduate medical students. Kathmandu Univ Med J (KUMJ). 2012 Jul-Sep;10(39):56-9. doi: 10.3126/kumj.v10i3.8021. PMID: 23434964.
  13. Olum R, Nakwagala FN, Odokonyero R. Prevalence and Factors Associated with Depression among Medical Students at Makerere University, Uganda. Adv Med Educ Pract. 2020 Nov 12;11:853-860. doi: 10.2147/AMEP.S278841. PMID: 33209071; PMCID: PMC7669518.
  14. Othieno CJ, Okoth RO, Peltzer K, Pengpid S, Malla LO. Depression among university students in Kenya: prevalence and sociodemographic correlates. J Affect Disord. 2014 Aug;165:120-5. doi: 10.1016/j.jad.2014.04.070. Epub 2014 May 4. PMID: 24882188.
  15. Melo-Carrillo A, Van Oudenhove L, Lopez-Avila A. Depressive symptoms among Mexican medical students: high prevalence and the effect of a group psychoeducation intervention. J Affect Disord. 2012 Feb;136(3):1098-103. doi: 10.1016/j.jad.2011.10.040. Epub 2011 Nov 25. PMID: 22119092.
  16. Sarokhani D, Delpisheh A, Veisani Y, Sarokhani MT, Manesh RE, Sayehmiri K. Prevalence of Depression among University Students: A Systematic Review and Meta-Analysis Study. Depress Res Treat. 2013;2013:373857. doi: 10.1155/2013/373857. Epub 2013 Sep 25. PMID: 24187615; PMCID: PMC3800630.
  17. Ahmed I, Banu H, Al-Fageer R, Al-Suwaidi R. Cognitive emotions: depression and anxiety in medical students and staff. J Crit Care. 2009 Sep;24(3):e1-7. doi: 10.1016/j.jcrc.2009.06.003. PMID: 19664516.
  18. Aktekin M, Karaman T, Senol YY, Erdem S, Erengin H, Akaydin M. Anxiety, depression and stressful life events among medical students: a prospective study in Antalya, Turkey. Med Educ. 2001 Jan;35(1):12-7. doi: 10.1046/j.1365-2923.2001.00726.x. PMID: 11123589.
  19. Supe AN. A study of stress in medical students at Seth G.S. Medical College. J Postgrad Med. 1998 Jan-Mar;44(1):1-6. PMID: 10703558.
  20. Dyrbye LN, Thomas MR, Shanafelt TD. Medical student distress: causes, consequences, and proposed solutions. Mayo Clin Proc. 2005 Dec;80(12):1613-22. doi: 10.4065/80.12.1613. PMID: 16342655.
  21. Bayram N, Bilgel N. The prevalence and socio-demographic correlations of depression, anxiety and stress among a group of university students. Soc Psychiatry Psychiatr Epidemiol. 2008 Aug;43(8):667-72. doi: 10.1007/s00127-008-0345-x. Epub 2008 Apr 8. PMID: 18398558.
  22. Higgins J, Green S. Cochrane handbook for systematic reviews of interventions, vol version 5.1.0. London: The cochrane collaboration. 2011.
  23. Liberati A, Altman DG, Tetzlaff J, Mulrow C, Gøtzsche PC, Ioannidis JP, Clarke M, Devereaux PJ, Kleijnen J, Moher D. The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. PLoS Med. 2009 Jul 21;6(7):e1000100. doi: 10.1371/journal.pmed.1000100. Epub 2009 Jul 21. PMID: 19621070; PMCID: PMC2707010.
  24. Critical Skills Appraisal Programme CASP UK. 2013.
  25. BETs CA Worksheets. BestBETs. 2013.
  26. Review manager. Version 5.1: The Nordic Cochrane Centre. 5.1 ed. Copenhagen: The Cochrane Collaboration. RevMan. 2011.
  27. Aveyard H. Why do a literature review in health and social care? Doing a literature review in health and social care. A practical guide. Berkshire: McGraw-Hill Education. 2007;5-21.
  28. Centers for Disease Control and Prevention (CDC). Current depression among adults---United States, 2006 and 2008. MMWR Morb Mortal Wkly Rep. 2010 Oct 1;59(38):1229-35. PMID: 20881934.
  29. Andrade L, Caraveo-Anduaga JJ, Berglund P, Bijl RV, De Graaf R, Vollebergh W, Dragomirecka E, Kohn R, Keller M, Kessler RC, Kawakami N, Kiliç C, Offord D, Ustun TB, Wittchen HU. The epidemiology of major depressive episodes: results from the International Consortium of Psychiatric Epidemiology (ICPE) Surveys. Int J Methods Psychiatr Res. 2003;12(1):3-21. doi: 10.1002/mpr.138. Erratum in: Int J Methods Psychiatr Res. 2003;12(3):165. PMID: 12830306; PMCID: PMC6878531.
  30. Goldney RD, Eckert KA, Hawthorne G, Taylor AW. Changes in the prevalence of major depression in an Australian community sample between 1998 and 2008. Aust N Z J Psychiatry. 2010 Oct;44(10):901-10. doi: 10.3109/00048674.2010.490520. PMID: 20932204.
  31. Newman DL, Moffitt TE, Caspi A, Magdol L, Silva PA, Stanton WR. Psychiatric disorder in a birth cohort of young adults: prevalence, comorbidity, clinical significance, and new case incidence from ages 11 to 21. J Consult Clin Psychol. 1996 Jun;64(3):552-62. PMID: 8698949.
  32. Depression & suicide among college students: A fact sheet for physicians. National Institute of Mental Health (NIMH). 2009;700-744.
  33. Blanco C, Okuda M, Wright C, Hasin DS, Grant BF, Liu SM, Olfson M. Mental health of college students and their non-college-attending peers: results from the National Epidemiologic Study on Alcohol and Related Conditions. Arch Gen Psychiatry. 2008 Dec;65(12):1429-37. doi: 10.1001/archpsyc.65.12.1429. PMID: 19047530; PMCID: PMC2734947.
  34. Ceyhan A, Ceyhan E, Kurty Y. Investigation of university students’ depression. Eurasian Journal of Educational Research. 2009;36:75-90.
  35. Yeung A, Howarth S, Chan R, Sonawalla S, Nierenberg AA, Fava M. Use of the Chinese version of the Beck Depression Inventory for screening depression in primary care. J Nerv Ment Dis. 2002 Feb;190(2):94-9. doi: 10.1097/00005053-200202000-00005. PMID: 11889362.
  36. Su KP, Chiu TH, Huang CL, Ho M, Lee CC, Wu PL, Lin CY, Liau CH, Liao CC, Chiu WC, Pariante CM. Different cutoff points for different trimesters? The use of Edinburgh Postnatal Depression Scale and Beck Depression Inventory to screen for depression in pregnant Taiwanese women. Gen Hosp Psychiatry. 2007 Sep-Oct;29(5):436-41. doi: 10.1016/j.genhosppsych.2007.05.005. PMID: 17888811.
  37. Katon W, Schulberg H. Epidemiology of depression in primary care. Gen Hosp Psychiatry. 1992 Jul;14(4):237-47. doi: 10.1016/0163-8343(92)90094-q. PMID: 1505745.
  38. Poole H, Bramwell R, Murphy P. The utility of the Beck Depression Inventory Fast Screen (BDI-FS) in a pain clinic population. Eur J Pain. 2009 Sep;13(8):865-9. doi: 10.1016/j.ejpain.2008.09.017. Epub 2008 Nov 14. PMID: 19010075.
  39. Ayuso-Mateos JL, Vázquez-Barquero JL, Dowrick C, Lehtinen V, Dalgard OS, Casey P, Wilkinson C, Lasa L, Page H, Dunn G, Wilkinson G; ODIN Group. Depressive disorders in Europe: prevalence figures from the ODIN study. Br J Psychiatry. 2001 Oct;179:308-16. doi: 10.1192/bjp.179.4.308. PMID: 11581110.
  40. Martin A, Rief W, Klaiberg A, Braehler E. Validity of the Brief Patient Health Questionnaire Mood Scale (PHQ-9) in the general population. Gen Hosp Psychiatry. 2006 Jan-Feb;28(1):71-7. doi: 10.1016/j.genhosppsych.2005.07.003. PMID: 16377369.
  41. Yu X, Stewart SM, Wong PT, Lam TH. Screening for depression with the Patient Health Questionnaire-2 (PHQ-2) among the general population in Hong Kong. J Affect Disord. 2011 Nov;134(1-3):444-7. doi: 10.1016/j.jad.2011.05.007. Epub 2011 Jun 12. PMID: 21665288.
  42. Fawzy M, El-Maghraby Z, El-Amin H, Sahloul M. The Zagazig depression scale manual. Cairo: El-Nahda El-Massriya (in Arabic). 1982.
  43. Ibrahim AK, Kelly SJ, Glazebrook C. Analysis of an Egyptian study on the socioeconomic distribution of depressive symptoms among undergraduates. Soc Psychiatry Psychiatr Epidemiol. 2012 Jun;47(6):927-37. doi: 10.1007/s00127-011-0400-x. Epub 2011 May 31. PMID: 21626055.
  44. Carroll BJ, Feinberg M, Smouse PE, Rawson SG, Greden JF. The Carroll rating scale for depression. I. Development, reliability and validation. Br J Psychiatry. 1981 Mar;138:194-200. doi: 10.1192/bjp.138.3.194. PMID: 7272609.
  45. Van de Velde S, Bracke P, Meuleman B. Gender differences in depression in 25 European countries after eliminating measurement bias in the CES-D. Social Science Research. 2010;39:396-404. doi: 10.1016/j.ssresearch.2010.01.002.
  46. Ghodasara SL, Davidson MA, Reich MS, Savoie CV, Rodgers SM. Assessing student mental health at the Vanderbilt University School of Medicine. Acad Med. 2011 Jan;86(1):116-21. doi: 10.1097/ACM.0b013e3181ffb056. PMID: 21099385.
  47. Ben-Ezra M, Essar N. Depression and anxiety in developing countries. Lancet. 2004 Oct 23-29;364(9444):1488. doi: 10.1016/S0140-6736(04)17269-3. PMID: 15500892.
  48. Nutbrown C. A student’s guide to methodology. 2nd ed. London: Sage Publications Ltd. 2007.
  49. Bonita R, Beaglehole R, Kjellstrom T. Basic epidemiology. 2nd ed. Geneva: WHO. 2006.
  50. Dubben HH, Beck-Bornholdt HP. Systematic review of publication bias in studies on publication bias. BMJ. 2005 Aug 20;331(7514):433-4. doi: 10.1136/bmj.38478.497164.F7. Epub 2005 Jun 3. PMID: 15937056; PMCID: PMC1188109.
  51. Denscombe M. The length of responses to open-ended questions: a comparison of online and paper questionnaires in terms of a mode effect. Social Science Computer Review. (2008);26:359-68.
  52. Denscombe M. Item non-response rates: a comparison of online and paper questionnaires. International Journal of Social Research Methodology. (2009);12:281-91. doi: 10.1080/13645570802054706.
  53. Adewuya AO, Ola BA, Afolabi OO. Validity of the patient health questionnaire (PHQ-9) as a screening tool for depression amongst Nigerian university students. J Affect Disord. 2006 Nov;96(1-2):89-93. doi: 10.1016/j.jad.2006.05.021. Epub 2006 Jul 20. PMID: 16857265.
  54. Tesera B, Wohabie B. The potential effect of depression on academic outcomes of students in higher educational institutions of northwest Ethiopia. Educational research and reviews. 2020;16(1):9-15.
  55. Elsawy WIH, Sherif AAR, Attia MSED, El-Nimr NA. Depression among medical students in Alexandria, Egypt. Afr Health Sci. 2020 Sep;20(3):1416-1425. doi: 10.4314/ahs.v20i3.47. PMID: 33402990; PMCID: PMC7751550.
  56. Sarokhani D, Delpisheh A, Veisani Y, Sarokhani MT, Manesh RE, Sayehmiri K. Prevalence of Depression among University Students: A Systematic Review and Meta-Analysis Study. Depress Res Treat. 2013;2013:373857. doi: 10.1155/2013/373857. Epub 2013 Sep 25. PMID: 24187615; PMCID: PMC3800630.
  57. Garlow SJ, Rosenberg J, Moore JD, Haas AP, Koestner B, Hendin H, Nemeroff CB. Depression, desperation, and suicidal ideation in college students: results from the American Foundation for Suicide Prevention College Screening Project at Emory University. Depress Anxiety. 2008;25(6):482-8. doi: 10.1002/da.20321. PMID: 17559087.
  58. Aalto-Setälä T, Marttunen M, Tuulio-Henriksson A, Poikolainen K, Lönnqvist J. One-month prevalence of depression and other DSM-IV disorders among young adults. Psychol Med. 2001 Jul;31(5):791-801. doi: 10.1017/s0033291701004081. PMID: 11459377.


Comments


Swift, Reliable, and studious. We aim to cherish the world by publishing precise knowledge.

  • asd
  • Brown University Library
  • University of Glasgow Library
  • University of Pennsylvania, Penn Library
  • University of Amsterdam Library
  • The University of British Columbia Library
  • UC Berkeley’s Library
  • MIT Libraries
  • Kings College London University
  • University of Texas Libraries
  • UNSW Sidney Library
  • The University of Hong Kong Libraries
  • UC Santa Barbara Library
  • University of Toronto Libraries
  • University of Oxford Library
  • Australian National University
  • ScienceOpen
  • UIC Library
  • KAUST University Library
  • Cardiff University Library
  • Ball State University Library
  • Duke University Library
  • Rutgers University Library
  • Air University Library
  • UNT University of North Texas
  • Washington Research Library Consortium
  • Penn State University Library
  • Georgetown Library
  • Princeton University Library
  • Science Gate
  • Internet Archive
  • WashingTon State University Library
  • Dimensions
  • Zenodo
  • OpenAire
  • Index Copernicus International
  • icmje
  •  International Scientific Indexing (ISI)
  • Sherpa Romeo
  • ResearchGate
  • Universidad De Lima
  • WorldCat
  • JCU Discovery
  • McGill
  • National University of Singepore Libraries
  • SearchIT
  • Scilit
  • SemantiScholar
  • Base Search
  • VU
  • KB
  • Publons
  • oaji
  • Harvard University
  • sjsu-library
  • UWLSearch
  • Florida Institute of Technology
  • CrossRef
  • LUBsearch
  • Universitat de Paris
  • Technical University of Denmark
  • ResearchBIB
  • Google Scholar
  • Microsoft Academic Search