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The Target of Chemoprevention for Gastric Cancer

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Open Access
Article Type Opinion
Subject Medicine Group
OCLC 9528699572
Shaoqing Lai* and Yaxiaer Rezhayiding
Issue: Volume3-Issue5
Pages: 602-606
Received: 2022-05-10
Accepted: 2022-05-23
Published: 2022-05-25

Abstract

Gastric Cancer (GC) is the fifth leading cancer in the world and the third leading cause of cancer-related death. The 5-year survival rate of advanced gastric cancer is less than 30%, it is very important to prevent gastric cancer. Current methods to prevent gastric cancer are eradication of H. pylori, early endoscopic diagnosis and early treatment. Chemoprevention of cancer is using of natural, synthetic, or biological substances to prevent, or reverse the development of cancer, thereby reducing the incidence and mortality of cancer. We will discuss the target of chemoprevention for gastric cancer based on the clue of regeneration of gastric mucosal epithelium from the perspectives of gastric stem cell proliferation and differentiation.

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© 2022 Lai S. Distributed under Creative Commons CC-BY 4.0 Creative CommonsAttribution

How to cite this article

Lai S. The Target of Chemoprevention for Gastric Cancer. J Biomed Res Environ Sci. 2022 May 25; 3(5): 602-606. doi: 10.37871/jbres1486, Article ID: JBRES1486, Available at: https://www.jelsciences.com/articles/jbres1486.pdf

Subject area(s)

OncologyCancerGastroenterology

References

  1. Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, Bray F. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin. 2021 May;71(3):209-249. doi: 10.3322/caac.21660. Epub 2021 Feb 4. PMID: 33538338.
  2. Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D. Global cancer statistics. CA Cancer J Clin. 2011 Mar-Apr;61(2):69-90. doi: 10.3322/caac.20107. Epub 2011 Feb 4. Erratum in: CA Cancer J Clin. 2011 Mar-Apr;61(2):134. PMID: 21296855.
  3. Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018 Nov;68(6):394-424. doi: 10.3322/caac.21492. Epub 2018 Sep 12. Erratum in: CA Cancer J Clin. 2020 Jul;70(4):313. PMID: 30207593.
  4. Howson CP, Hiyama T, Wynder EL. The decline in gastric cancer: epidemiology of an unplanned triumph. Epidemiol Rev. 1986;8:1-27. doi: 10.1093/oxfordjournals.epirev.a036288. PMID: 3533579.
  5. Coggon D, Barker DJ, Cole RB, Nelson M. Stomach cancer and food storage. J Natl Cancer Inst. 1989 Aug 2;81(15):1178-82. doi: 10.1093/jnci/81.15.1178. PMID: 2746670.
  6. Powell J, McConkey CC. Increasing incidence of adenocarcinoma of the gastric cardia and adjacent sites. Br J Cancer. 1990 Sep;62(3):440-3. doi: 10.1038/bjc.1990.314. PMID: 2206952; PMCID: PMC1971432.
  7. Edge SB, Compton CC. The American Joint Committee on Cancer: the 7th edition of the AJCC cancer staging manual and the future of TNM. Ann Surg Oncol. 2010 Jun;17(6):1471-4. doi: 10.1245/s10434-010-0985-4. PMID: 20180029.
  8. LAUREN P. THE TWO HISTOLOGICAL MAIN TYPES OF GASTRIC CARCINOMA: DIFFUSE AND SO-CALLED INTESTINAL-TYPE CARCINOMA. AN ATTEMPT AT A HISTO-CLINICAL CLASSIFICATION. Acta Pathol Microbiol Scand. 1965;64:31-49. doi: 10.1111/apm.1965.64.1.31. PMID: 14320675.
  9. Cancer Genome Atlas Research Network. Comprehensive molecular characterization of gastric adenocarcinoma. Nature. 2014 Sep 11;513(7517):202-9. doi: 10.1038/nature13480. Epub 2014 Jul 23. PMID: 25079317; PMCID: PMC4170219.
  10. Meyskens FL Jr, Mukhtar H, Rock CL, Cuzick J, Kensler TW, Yang CS, Ramsey SD, Lippman SM, Alberts DS. Cancer Prevention: Obstacles, Challenges and the Road Ahead. J Natl Cancer Inst. 2015 Nov 7;108(2):djv309. doi: 10.1093/jnci/djv309. PMID: 26547931; PMCID: PMC4907357.
  11. Stoner GD, Morse MA, Kelloff GJ. Perspectives in cancer chemoprevention. Environ Health Perspect. 1997 Jun;105 Suppl 4(Suppl 4):945-54. doi: 10.1289/ehp.97105s4945. PMID: 9255586; PMCID: PMC1470021.
  12. Barker N, Huch M, Kujala P, van de Wetering M, Snippert HJ, van Es JH, Sato T, Stange DE, Begthel H, van den Born M, Danenberg E, van den Brink S, Korving J, Abo A, Peters PJ, Wright N, Poulsom R, Clevers H. Lgr5(+ve) stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro. Cell Stem Cell. 2010 Jan 8;6(1):25-36. doi: 10.1016/j.stem.2009.11.013. PMID: 20085740.
  13. Chen S, Lewallen M, Xie T. Adhesion in the stem cell niche: biological roles and regulation. Development. 2013 Jan 15;140(2):255-65. doi: 10.1242/dev.083139. PMID: 23250203; PMCID: PMC3597204.
  14. Yoku Hayakawa, Hiroshi Ariyama, JitkaStancikova, Daniel L. Worthley, Vladimir Korinek, Timothy C. Wang Mistl expressing gastric stem cells maintain the normal and neoplastic gastric epithelium and are supported by a perivascular stem cell niche [J] Cancer Cell 2015 28(6):800-814. DOI:10.1016/j. ccell.2015. 10.003
  15. Mills JC, Shivdasani RA. Gastric epithelial stem cells. Gastroenterology. 2011 Feb;140(2):412-24. doi: 10.1053/j.gastro.2010.12.001. Epub 2010 Dec 7. PMID: 21144849; PMCID: PMC3708552.
  16. Karam SM. Lineage commitment and maturation of epithelial cells in the gut. Front Biosci. 1999 Mar 15;4:D286-98. doi: 10.2741/karam. PMID: 10077541.
  17. Karam SM. Cell lineage relationship in the stomach of normal and genetically manipulated mice. Braz J Med Biol Res. 1998 Feb;31(2):271-9. doi: 10.1590/s0100-879x1998000200010. PMID: 9686149.
  18. Li Q, Jia Z, Wang L, Kong X, Li Q, Guo K, Tan D, Le X, Wei D, Huang S, Mishra L, Xie K. Disruption of Klf4 in villin-positive gastric progenitor cells promotes formation and progression of tumors of the antrum in mice. Gastroenterology. 2012 Mar;142(3):531-42. doi: 10.1053/j.gastro.2011.11.034. Epub 2011 Dec 7. PMID: 22155367; PMCID: PMC3477581.
  19. Dias-Neto M, Pintalhao M, Ferreira M, Lunet N. Salt intake and risk of gastric intestinal metaplasia: systematic review and meta-analysis. Nutr Cancer. 2010;62(2):133-47. doi: 10.1080/01635580903305391. PMID: 20099187.
  20. Song JH, Kim YS, Heo NJ, Lim JH, Yang SY, Chung GE, Kim JS. High Salt Intake Is Associated with Atrophic Gastritis with Intestinal Metaplasia. Cancer Epidemiol Biomarkers Prev. 2017 Jul;26(7):1133-1138. doi: 10.1158/1055-9965.EPI-16-1024. Epub 2017 Mar 24. PMID: 28341758.
  21. Thapa S, Fischbach LA, Delongchamp R, Faramawi MF, Orloff M. Association between Dietary Salt Intake and Progression in the Gastric Precancerous Process. Cancers (Basel). 2019 Apr 3;11(4):467. doi: 10.3390/cancers11040467. PMID: 30987215; PMCID: PMC6520970.
  22. Parsonnet J, Friedman GD, Vandersteen DP, Chang Y, Vogelman JH, Orentreich N, Sibley RK. Helicobacter pylori infection and the risk of gastric carcinoma. N Engl J Med. 1991 Oct 17;325(16):1127-31. doi: 10.1056/NEJM199110173251603. PMID: 1891020.
  23. Lee YC, Chiang TH, Chou CK, Tu YK, Liao WC, Wu MS, Graham DY. Association Between Helicobacter pylori Eradication and Gastric Cancer Incidence: A Systematic Review and Meta-analysis. Gastroenterology. 2016 May;150(5):1113-1124.e5. doi: 10.1053/j.gastro.2016.01.028. Epub 2016 Feb 2. PMID: 26836587.
  24. Levi S, Beardshall K, Haddad G, Playford R, Ghosh P, Calam J. Campylobacter pylori and duodenal ulcers: the gastrin link. Lancet. 1989 May 27;1(8648):1167-8. doi: 10.1016/s0140-6736(89)92752-9. PMID: 2566737.
  25. Uemura N, Okamoto S, Yamamoto S, Matsumura N, Yamaguchi S, Yamakido M, Taniyama K, Sasaki N, Schlemper RJ. Helicobacter pylori infection and the development of gastric cancer. N Engl J Med. 2001 Sep 13;345(11):784-9. doi: 10.1056/NEJMoa001999. PMID: 11556297.
  26. Malfertheiner P. The intriguing relationship of Helicobacter pylori infection and acid secretion in peptic ulcer disease and gastric cancer. Dig Dis. 2011;29(5):459-64. doi: 10.1159/000332213. Epub 2011 Nov 16. PMID: 22095010.
  27. Wong BC, Lam SK, Wong WM, Chen JS, Zheng TT, Feng RE, Lai KC, Hu WH, Yuen ST, Leung SY, Fong DY, Ho J, Ching CK, Chen JS; China Gastric Cancer Study Group. Helicobacter pylori eradication to prevent gastric cancer in a high-risk region of China: a randomized controlled trial. JAMA. 2004 Jan 14;291(2):187-94. doi: 10.1001/jama.291.2.187. PMID: 14722144.
  28. Kiriyama Y, Tahara T, Shibata T, Okubo M , NakagawaM, Okabe A, Ohmiya N, Kuroda M, Sugioka A, Ichinose M, Tatematsu M, Tsukamoto T. Gastric-and-intestinal mixed intestinal metaplasia is irreversible point with eradication of Helicobacter pylori. Open J Pathology. 2016;6(1):93-104. doi: 10.4236/ojpathology.2016.62012.
  29. Korman MG, Strickland RG, Hansky J. Serum gastrin in chronic gastritis. Br Med J. 1971 Apr 3;2(5752):16-8. doi: 10.1136/bmj.2.5752.16. PMID: 5550864; PMCID: PMC1795895.
  30. Pounder R. Changes of plasma gastrin concentration associated with drugs forpeptic ulceration. In: Walsh JH, editor. Gastrin. New York, NY: Raven Press. 1993. p. 319–34.
  31. Waldum HL, Hauso Ø, Sørdal ØF, Fossmark R. Gastrin May Mediate the Carcinogenic Effect of Helicobacter pylori Infection of the Stomach. Dig Dis Sci. 2015 Jun;60(6):1522-7. doi: 10.1007/s10620-014-3468-9. Epub 2014 Dec 6. PMID: 25480404.
  32. Mahr S, Neumayer N, Gerhard M, Classen M, Prinz C. IL-1beta-induced apoptosis in rat gastric enterochromaffin-like cells is mediated by iNOS, NF-kappaB, and Bax protein. Gastroenterology. 2000 Mar;118(3):515-24. doi: 10.1016/s0016-5085(00)70257-5. PMID: 10702202.
  33. Zhang B, Rong G, Wei H, Zhang M, Bi J, Ma L, Xue X, Wei G, Liu X, Fang G. The prevalence of Th17 cells in patients with gastric cancer. Biochem Biophys Res Commun. 2008 Sep 26;374(3):533-7. doi: 10.1016/j.bbrc.2008.07.060. Epub 2008 Jul 23. PMID: 18655770.
  34. Yamada Y, Saito H, Ikeguchi M. Prevalence and clinical relevance of Th17 cells in patients with gastric cancer. J Surg Res. 2012 Dec;178(2):685-91. doi: 10.1016/j.jss.2012.07.055. Epub 2012 Aug 9. PMID: 22940035.
  35. Li Q, Li Q, Chen J, Liu Y, Zhao X, Tan B, Ai J, Zhang Z, Song J, Shan B. Prevalence of Th17 and Treg cells in gastric cancer patients and its correlation with clinical parameters. Oncol Rep. 2013 Sep;30(3):1215-22. doi: 10.3892/or.2013.2570. Epub 2013 Jun 27. PMID: 23807713.
  36. Bockerstett KA, Osaki LH, Petersen CP, Cai CW, Wong CF, Nguyen TM, Ford EL, Hoft DF, Mills JC, Goldenring JR, DiPaolo RJ. Interleukin-17A Promotes Parietal Cell Atrophy by Inducing Apoptosis. Cell Mol Gastroenterol Hepatol. 2018 Jan 2;5(4):678-690.e1. doi: 10.1016/j.jcmgh.2017.12.012. PMID: 29930985; PMCID: PMC6009015.
  37. De Block CE, De Leeuw IH, Van Gaal LF. Autoimmune gastritis in type 1 diabetes: a clinically oriented review. J Clin Endocrinol Metab. 2008 Feb;93(2):363-71. doi: 10.1210/jc.2007-2134. Epub 2007 Nov 20. PMID: 18029461.
  38. Cheung KS, Chan EW, Wong AYS, Chen L, Wong ICK, Leung WK. Long-term proton pump inhibitors and risk of gastric cancer development after treatment for Helicobacter pylori: a population-based study. Gut. 2018 Jan;67(1):28-35. doi: 10.1136/gutjnl-2017-314605. Epub 2017 Oct 31. PMID: 29089382.
  39. Miao ZF, Adkins-Threats M, Burclaff JR, Osaki LH, Sun JX, Kefalov Y, He Z, Wang ZN, Mills JC. A Metformin-Responsive Metabolic Pathway Controls Distinct Steps in Gastric Progenitor Fate Decisions and Maturation. Cell Stem Cell. 2020 Jun 4;26(6):910-925.e6. doi: 10.1016/j.stem.2020.03.006. Epub 2020 Apr 2. PMID: 32243780; PMCID: PMC7275895.
  40. LAUREN P. The Two Histological Main Types Of Gastric Carcinoma: Diffuse And So-Called Intestinal-Type Carcinoma. An Attempt At A Histo-Clinical Classification. Acta Pathol Microbiol Scand. 1965;64:31-49. doi: 10.1111/apm.1965.64.1.31. PMID: 14320675.
  41. Correa P. Human gastric carcinogenesis: a multistep and multifactorial process--First American Cancer Society Award Lecture on Cancer Epidemiology and Prevention. Cancer Res. 1992 Dec 15;52(24):6735-40. PMID: 1458460.
  42. Graham DY, Zou WY. Guilt by association: intestinal metaplasia does not progress to gastric cancer. Curr Opin Gastroenterol. 2018 Nov;34(6):458-464. doi: 10.1097/MOG.0000000000000472. PMID: 30138135; PMCID: PMC6913177.
  43. MORSON BC. Intestinal metaplasia of the gastric mucosa. Br J Cancer. 1955 Sep;9(3):365-76. doi: 10.1038/bjc.1955.35. PMID: 13269634; PMCID: PMC2073705.
  44. Kinoshita H, Hayakawa Y, Koike K. Metaplasia in the Stomach-Precursor of Gastric Cancer? Int J Mol Sci. 2017 Sep 27;18(10):2063. doi: 10.3390/ijms18102063. PMID: 28953255; PMCID: PMC5666745.
  45. Graham DY, Zou WY. Guilt by association: intestinal metaplasia does not progress to gastric cancer. Curr Opin Gastroenterol. 2018 Nov;34(6):458-464. doi: 10.1097/MOG.0000000000000472. PMID: 30138135; PMCID: PMC6913177.
  46. Tatematsu M, Tsukamoto T, Inada K. Stem cells and gastric cancer: role of gastric and intestinal mixed intestinal metaplasia. Cancer Sci. 2003 Feb;94(2):135-41. doi: 10.1111/j.1349-7006.2003.tb01409.x. PMID: 12708487.
  47. Bartley AN, Rashid A, Fournier KF, Abraham SC. Neuroendocrine and mucinous differentiation in signet ring cell carcinoma of the stomach: evidence for a common cell of origin in composite tumors. Hum Pathol. 2011 Oct;42(10):1420-9. doi: 10.1016/j.humpath.2010.12.008. Epub 2011 Mar 21. PMID: 21419473.
  48. Kirchner T, Müller S, Hattori T, Mukaisyo K, Papadopoulos T, Brabletz T, Jung A. Metaplasia, intraepithelial neoplasia and early cancer of the stomach are related to dedifferentiated epithelial cells defined by cytokeratin-7 expression in gastritis. Virchows Arch. 2001 Oct;439(4):512-22. doi: 10.1007/s004280100477. PMID: 11710638.
  49. Humar B, Fukuzawa R, Blair V, Dunbier A, More H, Charlton A, Yang HK, Kim WH, Reeve AE, Martin I, Guilford P. Destabilized adhesion in the gastric proliferative zone and c-Src kinase activation mark the development of early diffuse gastric cancer. Cancer Res. 2007 Mar 15;67(6):2480-9. doi: 10.1158/0008-5472.CAN-06-3021. PMID: 17363565.
  50. Tsukamoto T. Pathology of gastric cancer.Liaoning Science and Technology Publishing House. 2020,1. ISBN 978-7-5591-1312-2
  51. Grossi C, Lattes R. Carcinoid tumors of the stomach. Cancer. 1956;9:698–711.
  52. Waldum HL, Brenna E, Sandvik AK. Relationship of ECL cells and gastric neoplasia. Yale J Biol Med. 1998 May-Aug;71(3-4):325-35. PMID: 10461363; PMCID: PMC2578987.
  53. Whitehead R, Cosgrove C. Mucins and carcinoid tumours. Pathology. 1979 Jul;11(3):473-8. doi: 10.3109/00313027909059024. PMID: 523185.
  54. Waldum HL, Aase S, Kvetnoi I, Brenna E, Sandvik AK, Syversen U, Johnsen G, Vatten L, Polak JM. Neuroendocrine differentiation in human gastric carcinoma. Cancer. 1998 Aug 1;83(3):435-44. PMID: 9690535.
  55. Waldum H, Haugen O, Isaksen C, Mecsei R, Sandvik A. Are diffuse gastric carcinomas neuroendocrine tumours (ECL-omas)?. Eur J GastroenterolHepatol. 1991;3(1):245–9.
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