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Review Article

Recent Developments and Applications of Single-Cell RNA Sequencing Technology in Cell Classification

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Open Access
Article Type Review Article
Subject Biology Group
OCLC 9385833448
Safir Ullah Khan* and Munir Ullah Khan
Issue: Volume2-Issue12
Pages: 1283-1290
Received: 2021-12-07
Accepted: 2021-12-27
Published: 2021-12-29

Abstract

Multicellular organisms have many cell types and are complex, and heterogeneity is common among cells. Single-Cell RNA Sequencing (scRNA-SEQ) is a new technique for studying the transcriptional activity of a single cell that is still in its early stages of development. It generates transcriptional profiles from thousands of parallel cells to reveal the differential expression of individual cell genomes. They reflect the heterogeneity between cells to identify different cell types and form cell maps of tissues or organs, which play an essential role in biology and clinical medicine. Based on the introduction and comparison of the scRNA-SEQ sequencing platform, this paper focuses on the application of scRNA-SEQ in the exploration of cell types in the nervous system and immune system and summarizes the research results of the combination of scRNA-SEQ and spatial transcriptome technology.

FullText HTML FullText PDF DOI: 10.37871/jbres1383 Crossmark

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© 2021 Khan SU, et al. Distributed under Creative Commons CC-BY 4.0 Creative CommonsAttribution

How to cite this article

Khan SU, Khan MU. Recent Developments and Applications of Single-Cell RNA Sequencing Technology in Cell Classification. J Biomed Res Environ Sci. 2021 Dec 29; 2(12): 1283-1290. doi: 10.37871/jbres1383, Article ID: JBRES1383, Available at: https://www.jelsciences.com/articles/jbres1383.pdf

Subject area(s)

Molecular BiologyGenomicsBiology

University/Institute

University of Science and Technology of China

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