Covid-19 Research

Research Article

Pharmacognostical and Phytochemical Screening of GC–MS Analysis of Bioactive Compounds Present in Ethanolic Rhizome Extract of Zingiber officinale Roscoe

Journal of Biomedical Research & Environmental Sciences article abstract with citation details, DOI, publication dates, subject areas, full text links, and references.

View DOI Submit Manuscript

Article Details

Publication record, authors, dates, abstract, and full text access.

Open Access
Article Type Research Article
Subject Medicine Group
OCLC 9060760702
Azhagu Madhavan S*, Priyadharshini R, Sripriya R, Uma V and Vinotha P
Issue: Volume2-Issue5
Pages: 372-377
Received: 2021-05-13
Accepted: 2021-05-20
Published: 2021-05-22

Abstract

Nowadays, nanotechnology is used as a way to increase bioavailability and decrease the side effects of drugs and nutrients. Micronutrients and nutraceuticals such as vitamins, carotenoids, polyunsaturated fatty acids and polyphenols are classes of food ingredients that are essential for human health and well-being. These compounds are rarely added purely to the targeted food application but rather in encapsulated, solid, dry product forms with added functionalities such as improved stability, bioavailability or handling. Development of new strategies, like nanocarriers, that help to promote the access of neuroprotective molecules to the brain, is needed for providing more effective therapies for the disorders of the Central Nervous System (CNS). Polymer–lipid hybrid nanoparticles, encapsulating vitamin D3 and vitamin K2, with improved features in terms of stability, loading and mucoadhesiveness were produced for potential nutraceutical and pharmaceutical applications. Recently, nanoformulations that include nanovesicles, solid-lipid nanoparticles, nanostructured lipid carriers, nanoemulsions, and polymeric nanoparticles have shown promising outcomes in improving the efficacy and bioavailability of vitamin E. Active targeting of nanoparticles loaded with vitamin D to cancer cells.

FullText HTML FullText PDF DOI: 10.37871/jbres1244 Crossmark

Certificate of Publication

Certificate of Publication

Copyright

© 2021 Azhagu Madhavan S, et al. Distributed under Creative Commons CC-BY 4.0 Creative CommonsAttribution

How to cite this article

Azhagu Madhavan S, Priyadharshini R, Sripriya R, Uma V, Vinotha P. Pharmacognostical and Phytochemical Screening of GC–MS Analysis of Bioactive Compounds Present in Ethanolic Rhizome Extract of Zingiber officinale Roscoe. J Biomed Res Environ Sci. 2021 May 22; 2(5): 372-377. doi: 10.37871/jbres1244, Article ID: jbres1244

Subject area(s)

Pharmaceutica Analytica Acta

References

  1. Sushmitha HS, Balasubramanian Sathyamurthy. In Silico drug designing studies on Dengue Virus NS2BNS3 Protease. Indo American Journal of Pharmaceutical Sciences. 2018;5(8):7784-7790.
  2. https://bit.ly/2ShZi5W
  3. Babatunde DE, Otusemade GO, Ojewumi ME, Agboola O, Akinlabu KD, Oyeniyi E. Antimicrobial activity and phytochemical screening of neem leaves and lemon grass essential oil extracts. Int J Mech Eng Technol. 2019;10.
  4. https://bit.ly/3va4W8Q
  5. Eid A, Jaradat N, Elmarzugi N. A Review of chemical constituents and traditional usage of Neem plant (Azadirachta Indica). Palest Med Pharm J. 2017;2:75-81.
  6. Murugesan G, Nagaraj K, Sunmathi D, Subramani K. Methods involved in the synthesis of selenium nanoparticles and their different applications-a review. Eur J Biomed. 2019;6:189-194.
  7. Padalia RC, Verma RS, Sah AN, Karki N, Sundaresan V, Sakia D. Leaf and rhizome oil composition of Zingiber officinale Roscoe and their antibacterial and antioxidant activities. J Traditional Med. 2011;6(2):73-82.
  8. https://bit.ly/3fBBQIT
  9. Sasidharan I, Menon N. Comparative chemical composition and antimicrobial activity of Fresh and dry ginger oils (Zingiber officinale Roscoe). International J Cur Pharm Res. 2010;2(4):40-43.
  10. https://bit.ly/3vbUL3K
  11. Padmakumari KP, Sreekumar MM, Sankarikutty B. Composition of volatile oil of ginger (Z. officinale Roscoe) varieties from India. Indian Perfum. 2009;53:16-20.
  12. Baliga MS, Haniadka R, Pereira MM, Thilakchand KR, Rao S, Arora R. Radioprotective effects of Zingiber officinale Roscoe (ginger): past, present and future. Food Funct. 2012 Jul;3(7):714-23. doi: 10.1039/c2fo10225k. Epub 2012 May 18. PMID: 22596078.
  13. Khandelwal KR. Practical pharmacognosy techniques and experiments. New Delhi: Nirali Prakashan. 2002;15-163.
  14. Kokate CK. Practical Pharmacognosy. 1st ed. New Delhi: Vallabh Prakashan. 2005;111.
  15. Asghari-Paskiabi F, Imani M, Rafii-Tabar H, Razzaghi-Abyaneh M. Physicochemical properties, antifungal activity and cytotoxicity of selenium sulfide nanoparticles green synthesized by Saccharomyces cerevisiae. Biochem Biophys Res Commun. 2019 Sep 3;516(4):1078-1084. doi: 10.1016/j.bbrc.2019.07.007. Epub 2019 Jul 4. PMID: 31280861.
  16. Menon S, Agarwal H, Rajeshkumar S, Rosy PJ, Shanmugam VK. Investigating the antimicrobial activities of the biosynthesized selenium nanoparticles and its statistical analysis. BioNanoScience. 2020.
  17. Nogueira de Melo GA, Grespan R, Fonseca JP, Farinha TO, da Silva EL, Romero AL, Bersani-Amado CA, Cuman RK. Inhibitory effects of ginger (Zingiber officinale Roscoe) essential oil on leukocyte migration in vivo and in vitro. J Nat Med. 2011 Jan;65(1):241-6. doi: 10.1007/s11418-010-0479-5. Epub 2010 Oct 28. PMID: 20981498.
  18. Sivasothy Y, Chong WK, Hamid A, Eldeen IM, Sulaiman SF, Awang K. Essential oils of Zingiber officinale var. rubrum theilade and their antibacterial activities. Food Chemistry. 2011;124:514-517;
  19. Sivasothy Y, Chong WK, Hamid A, Eldeen IM, Sulaiman SF, Awang K. Directorate General of National Export Development. Ginger: Superior, hot export commodity for your health. Ministry of Trade of the Republic of Indonesia, Jakarta. 2016;1-9.
  20. Cahyono B, Satriadi H, Munfarida S. Antioxidant activity and total phenolic content in Red Ginger (Zingiber officinale) based drinks. IOP Conference Series: Earth and Environmental Science. 2018;102:1-9.
  21. Azhagu Madhavan S, Vinotha P, Uma V. Pharmacological and Anti-Cancer Activity of Ipomoea sepiaria Methanolic Extract against PC-3 Cell Line. Asian Journal of Advances in Medical Science. 2020;2(3):26-32.
  22. Kumar Sharma P, Singh V, Ali M. Chemical composition and antimicrobial activity of fresh rhizome essential oil of Zingiber officinale Roscoe. Pharmacognosy Journal. 2016;8:185-190.
  23. Hassan A, Abutalib A, Almagboul A, Kabbashi A. Antimicrobial activity of the rhizome essential oil of Zingiber officinale Roscoe. Advancement in Medicinal Plant Research. 2017;5:5-10.
  24. Sarda PD, Nagve AD, Salve BV, Prashar K, Warkhade BB. Zingiber officinale: phytochemical analysis and evaluation of antimicrobial activity in combination with commercial antibiotics. International Journal of Current Research. 2017;9(10):59107-59111.
  25. Srinivasan Krishnapura. Ginger rhizomes (Zingiber officinale): A spice with multiple health beneficial potentials. Pharma Nutrition. 2017;5:18-28.
  26. Mahadevi M, Azhagu Madhavan S. In vitro antioxidant properties and free radical scaveneing activity of aqueous extract of papaya root. Alochana Chakra Journal. 2020.
  27. Azhagu Madhavan S. GC–MS analysis of bioactive compounds present in ethanolic leaf extract acalypha indica. Asian Journal of Advances in Research. 2021;6(4):16-22.
  28. Azhagu Madhavan S, Mahadevi M, Ganesan S, Vinotha P, Uma V. Phytochemicals screening of physico-chemical parameters and fluorescence analysis of plant ethanolic leaf extract costus pictus. Asian Journal of Advances in Medical Science. 2021;2(4):24-30.
  29. Azhagu Madhavan S, Ganesan S. A study on establishment of phytochemical analysis of ethanolic extract of silybum marianum (l.) Gaertn. (milk thistle) seed extract. International Journal of Plant Biotechnology. 2020;6(2):1-9.
Publish with JBRES — Peer-reviewed, multidisciplinary Open Access with rapid review, DOI, and global visibility.
Double-Blind CrossRef DOI Discoverable
Submit Manuscript Membership