Cardiovascular & Vascular Diseases
Section Editors
Research Topics in this Section
Cardiovascular Diseases
49
Cardiovascular DiseasesThese topics are filtered from our journals helping to discover the community within the widespread of mult…
Clinical Cardiology
44
Clinical CardiologyThese topics are filtered from our journals helping to discover the community within the widespread of multi-di…
Hypertension
6
HypertensionThese topics are filtered from our journals helping to discover the community within the widespread of multi-disciplin…
Vascular Medicine
16
Vascular MedicineThese topics are filtered from our journals helping to discover the community within the widespread of multi-disc…
Recent Articles
50 articles
Open Access
Research Article 29 Apr 2026
Down-Regulation of Ephrin-B1 in Left Ventricular Non-Compaction
Background: Left Ventricular Non-Compaction (LVNC) is a rare cardiomyopathy with incompletely understood pathophysiological mechanisms. Ephrin-B1 (Ep), a key protein of cardiomyocyte lateral junctions, may play a role in…
7 Views 54 Downloads
Open Access
Research Article 27 Feb 2026
The Development of Acute Kidney Injury and Electrolyte Disorders in Relation to Different Cardioplegic Solutions used during Cardiac Surgery
Background: Acute Kidney Injury (AKI) is a serious complication after cardiac surgery. We sought to determine the possible onset of AKI in patients undergoing cardiac surgery with different cardioplegic solution during C…
13 Views 68 Downloads
Open Access
Perspective 27 Feb 2026
Music as Medicine: Transforming Cardiac Interventions with Physiological and Neurochemical Benefits
Music, deeply embedded in human culture, profoundly influences physiological and psychological states, showcasing remarkable potential within clinical environments, notably the catheterization laboratory (Cath Lab). This…
9 Views 68 Downloads
Open Access
Review Article 11 Nov 2025
Keto Diet May Worsen Coronary Artery Disease: Insights from Bethsaida Hospital’s Plant-Based Diet Experience
The ketogenic (keto) diet, characterized by high fat, moderate protein, and minimal carbohydrate intake, has surged in popularity due to its perceived efficacy in rapid weight loss. Nevertheless, accumulating evidence hi…
746 Views 64 Downloads
Open Access
Review Article 08 Oct 2025
The Beneficial Role of Exercise and Whole-Food Plant-Based Diet in Coronary Artery Disease Prevention and Management
Coronary Artery Disease (CAD) remains a critical global health issue, substantially contributing to morbidity and mortality worldwide. The strategic combination of Regular Physical Exercise (RPE) and a Whole-Food Plant-B…
1,686 Views 91 Downloads
Open Access
Perspective 19 Aug 2025
Artificial Intelligence and Robotics in Interventional Cardiology: Preparing for a Transformative Future
Cardiovascular Disease (CVD) remains the leading cause of death worldwide, despite significant advances in pharmacotherapy and interventional techniques. The emergence of Artificial Intelligence (AI) and robotics represe…
13 Views 84 Downloads
Open Access
Clinical Trials 18 Aug 2025
Measuring Nitric Oxide, Reversing Disease and Mitigating Restenosis through Plant-Based Diet and Lifestyle
Once underestimated, Nitric Oxide (NO) is now recognized as a crucial molecule in maintaining vascular health, supporting brain function, and modulating systemic diseases. Since its Nobel Prize-winning discovery in 1998,…
232 Views 76 Downloads
Open Access
Review Article 11 Aug 2025
Why we avoid Animal Products: Science and Success Behind Bethsaida Hospitals Whole-Food Plant-Based Cardiac Program
Cardiovascular disease remains the leading cause of morbidity and mortality globally, with atherosclerosis and restenosis as critical pathological contributors. Accumulating evidence suggests that diets high in animal pr…
315 Views 77 Downloads
Open Access
Perspective 11 Aug 2025
Harnessing Nutrition to Prevent Coronary Recoil in Drug-Coated Balloon Angioplasty: Insights from Bethsaida Hospital
The success of Drug-Coated Balloon (DCB) angioplasty hinges critically on effectively preventing coronary artery recoil, an acute elastic response that threatens procedural efficacy and long-term vessel patency. While te…
528 Views 79 Downloads
Open Access
Original Article 27 Jul 2025
The Veterans Affairs Lipid Optimization Reimagined - Quality Improvement Program Rationale and Methods
Background: Atherosclerotic cardiovascular disease (ASCVD) is a major contributor to morbidity and mortality in United States (US) Veterans and to healthcare costs in the United States Veterans Affairs (VA) Healthcare Sy…
227 Views 92 Downloads 1 Citation
Open Access
Original Article 09 Jul 2025
Evaluation of the Effect of Ligaria cuneifolia Infusion on Plasma Cholesterol and Liver and Kidney Function in Patients with Cardiovascular Risk
Ligaria cuneifolia (R. et P.) Tiegh. –Loranthaceae– (Lc), commonly used in traditional medicine, is believed to reduce total plasma cholesterol (TC) and improve blood flow. Objective: To evaluate the effect of inges…
7 Views 83 Downloads
Open Access
Opinion 09 Jul 2025
Cracks in the Evidence: Why Studies from COURAGE to ISCHEMIA Failed to Show Benefit of Stenting PCI
Percutaneous Coronary Intervention (PCI) with stenting remains widely utilized for managing Chronic Coronary Syndrome (CCS). However, landmark clinical trials such as COURAGE and ISCHEMIA have repeatedly shown no signifi…
616 Views 74 Downloads
Open Access
Mini Review 30 Jun 2025
Potential Benefits of the Dietary Approaches to Stop Hypertension in Cardiovascular Disease
Cardiovascular Diseases (CVDs) are the leading cause of mortality worldwide and a major public health concern due to their increasing prevalence, economic impact, and association with modifiable lifestyle factors such as…
929 Views 75 Downloads
Open Access
Perspective 30 Jun 2025
Transforming Cardiac Care through Plant-Based Diets: A Breakthrough Experience from Bethsaida Hospital, Indonesia
Seven years ago, at Bethsaida Hospital in Indonesia, Professor Dasaad Mulijono pioneered the integration of a Plant-Based Diet (PBD) into routine cardiac caresa paradigm shift that has dramatically improved outcomes for …
582 Views 85 Downloads
Open Access
Review Article 16 Jun 2025
Modulation of Inflammation in Cardiac Function after Myocardial Infarction
511 Views 77 Downloads
Open Access
Clinical Trials 14 Jun 2025
Gut Microbiota, Cardiovascular Innovation, and Lifestyle Medicine: Southeast Asia’s First Clinical Integration of TMAO Testing
Trimethylamine N-Oxide (TMAO) has emerged as a novel biomarker implicated in the pathogenesis and progression of various cardiometabolic conditions, including Coronary Artery Disease (CAD), stroke, type 2 diabetes mellit…
662 Views 80 Downloads
Open Access
Review Article 28 May 2025
The European Union Must Act Effectively for a New Plan of Action to Improve the Cardiovascular Health Burden of European citizens: A Narrative Review
This Narrative Review presents data describing the health burden of Cardiovascular Disease (CVD) within and across the WHO European Region. CVD remains the most common cause of death in the region. Large disparities in d…
3,140 Views 83 Downloads
Open Access
Case Series 14 May 2025
Multivessel Minimally Invasive Coronary Bypass with Aortic Crossclamp. Experience with 40 First Patients
Background: Minimally Invasive Coronary Revascularization (MICS-CABG) has been performed for over 20 years; however, their technical complexity, steep learning curves and absence of training programs explain the weak acc…
374 Views 75 Downloads
Open Access
Short Communication 12 May 2025
Autologous Angiogenic Cell Precursors- A Molecular Strategy for The Treatment of Heart Failure: Response to Biocardia’s Cardiamp HF Trial
507 Views 87 Downloads 1 Citation
Open Access
Mini Review 05 May 2025
Advancements and Challenges of AI-Based Tools as an Effective Personalized Medicine in the Future for the Early Diagnosis of Pulmonary Hypertension
Personalized medicine is the customizable approach to medical treatment and healthcare decisions for individual patients based on their unique genetic, environmental, and lifestyle factors. Integrating Artificial Intelli…
1,186 Views 98 Downloads
Open Access
Perspective 24 Apr 2025
How a Plant-Based Diet and Ultra-Low LDL Levels Can Reverse Atherosclerosis and Prevent Restenosis: A Breakthrough in Heart Health
Low-Density Lipoprotein Cholesterol (LDL-C) remains a key target in preventing and treating cardiovascular disease. Recent data and expert consensus increasingly support aggressive LDL-C lowering strategies, with emergin…
1,867 Views 96 Downloads 1 Citation
Open Access
Research Article 28 Mar 2025
Potential Use of Immunological Indices as Predictors of Bacterial Infections Following Cardiopulmonary Bypass Surgery in Elderly Patients
Cardiac surgery with Cardiopulmonary Bypass (CPB) induces postoperative immunological responses in patients. We aimed to determine changes in various immunological parameters in patients during and after cardiac surgery …
260 Views 140 Downloads 1 Citation
Open Access
Case Report 26 Nov 2024
Tricuspid Stenosis of a Complex Etiology in a 26-Year-Old Woman after Surgical Correction of Congenital Gerbode Defect, successfully treated with Percutaneous Balloon Valvuloplasty
Adults with Congenital Heart Disease (ACHD) are a constantly growing population that often presents significant challenges and requires a multidisciplinary approach. Therapeutic decisions must balance potential benefits …
212 Views 136 Downloads
Open Access
Case Report 30 Sep 2024
Stroke as the First Sign of Heart Tumor What the Neurologist should know about Heart
Primary heart cancers are rare, but cancer metastases occur much more often, which is why they are diagnosed mainly in non-oncology departments. Approximately 85% of heart cancers are benign, with myxoma predominating [1…
184 Views 119 Downloads
Open Access
Case Report 24 Jul 2024
Postural Orthostatic Tachycardia Syndrome (POTS) of Autoimmune Origin - Case and Review
Introduction: Postural Orthostatic Tachycardia Syndrome (POTS) belongs to a group of orthostatic intolerance syndromes. It is defined by the increase in heart rate ≥30 bpm or heart rate higher than 120/min during first…
3,063 Views 116 Downloads 1 Citation
Open Access
Research Article 06 Jun 2024
Association between Sedentary Behaviors, Tobacco Smoke, Epigenetics, and Cardiovascular Disease
The association between sedentary behavior or physical inactivity and risk for developing vascular aging, Cardiovascular (CVD) or Coronary Artery Disease (CAD) as well as developing risk factors for the disease is high. …
1,169 Views 97 Downloads
Open Access
Research Article 26 Feb 2024
Initial Clinical Experience with New Technology ePatchTM Extended Holter Monitoring
Introduction and objectives: Conventional methods of Holter (H) monitoring, data analysis and reporting can be inefficient, leading to high costs and long response times. Traditional H devices can be cumbersome to wear, …
4,268 Views 104 Downloads
Open Access
Clinical Trials 02 Feb 2024
Angiogenic Precursor Cell Treatment of Critical Limb Ischemia Decreases Ulcer Size, Amputation and Death Rate: Re-Examination of phase II ACP NO-CLI Trial Data
Introduction: Critical limb ischemia has a prevalence in the US of 1.33%, with mortality 15-20% and major amputation 10-40% per year. Stem cell treatment has emerged as a treatment option for the 45% of patients for who…
1,668 Views 149 Downloads 1 Citation
Open Access
Research Article 17 Jan 2024
Risk Factors for Early Bioprosthetic Heart Valve Degeneration in Patients with Rheumatic Fever
Background: Rheumatic Fever (RF) is an immunological disorder related to exposure to group a streptococcus and rheumatic heart disease is an important cause of valve replacement. Bioprosthetic valves tend to degenerate f…
1,124 Views 112 Downloads
Open Access
Short Communication 05 Jan 2024
Analysis of the Impact of Tourmaline and Terahertz-Infused Clothing on Heart Rate Variability
Introduction: Expanding upon prior investigations that identified advantageous Far Infrared (FIR) properties associated with two minerals, namely tourmaline and terahertz, across diverse domains, including health and med…
6,706 Views 128 Downloads
Open Access
Research Article 12 Dec 2023
The Value of Fetal Echocardiography for Early Detection of Congenital Heart Defects: A Report of our Experience in a Great Referral Heart Center in Iran
Background: Prenatal diagnosis of cardiac defects in fetus is of paramount importance to enable a better monitoring of heart defects and to allow planning a proper management. We reported our experience on fetal heart ec…
2,378 Views 94 Downloads
Open Access
Research Article 17 Nov 2023
Network Pharmacology Study of Huangqi-Huangjing in the Treatment of Diabetic Nephropathy and Diabetic Cardiomyopathy
Objective: To systematically investigate the mechanism of Huangqi-Huangjing in the treatment of Diabetic Nephropathy (DN) and Diabetic Cardiomyopathy (DC) using network pharmacology and molecular docking analysis. To pro…
1,204 Views 121 Downloads
Open Access
Mini Review 14 Nov 2023
Hypoxic Epicardium Contribution to Myocardial Repair
Epicardium, the outer epithelial layer of the heart forming from extracardiac primordium, plays a fundamental role in myocardial embryogenesis by generating epicardial-derived cells (cardiac fibroblasts, mesenchymal cell…
729 Views 100 Downloads
Open Access
Research Article 25 Oct 2023
TDI Analysis as Predictor of Positive Perugini Score in HFpEF Patients with Restrictive Phenotype
Cardiac amyloidosis is an important but underdiagnosed cause of heart failure with preserved ejection fraction (HFpEF). We analysed TDI doppler with echo to determine if there is a correlation with positive results in my…
744 Views 126 Downloads
Open Access
Research Article 15 Oct 2023
The Impact of COVID-19 Pandemic on Cardiovascular Diseases in Brazil
Background: The novel coronavirus pandemic is an international public health emergency due to the high contagious potential of the virus on a global scale and, similarly to what happened globally, Brazilian authorities t…
3,299 Views 114 Downloads
Open Access
Short Communication 20 Sep 2023
Cardiovascular Complications of SARS-CoV-2 (COVID-19) in Adults
Severe Acute Respiratory Syndrome-2 (COVID-19) was a devastating worldwide pandemic which affected multiple organs, resulting in significant mortality and morbidity. A hallmark of COVID-19 is the ability to mutate and in…
2,719 Views 109 Downloads
Open Access
Mini Review 13 Sep 2023
Prevalence, Predictors and Diagnosis of Cardiac Amyloidosis in Patients with Aortic Stenosis
Cardiac amyloidosis and aortic stenosis often share a common clinical phenotype, and are associated with morbidity and mortality if untreated. Cardiac amyloidosis is present in ~15% of patients with aortic stenosis. Clin…
599 Views 131 Downloads
Open Access
Mini Review 19 Aug 2023
Musculoskeletal Manifestations of Transthyretin Cardiac Amyloidosis
Transthyretin Cardiac Amyloidosis (ATTR-CA) is caused by the deposition of misfolded transthyretin fibrils, leading to restrictive cardiomyopathy and eventually death if untreated. ATTR-CA is associated with certain musc…
1,311 Views 91 Downloads
Open Access
Research Article 17 Aug 2023
Differential Expression of the MiT/TFE Transcription Factor Family in Vascular Endothelial Cells under Low Oscillatory Shear Stress
Low Oscillating Shear Stress (LOSS) is known to promote inflammation and atherosclerosis, impacting the phenotype and function of Vascular Endothelial Cells (VECs). The microphthalmia/transcription factor E (MiT/TFE) fam…
1,036 Views 103 Downloads
Open Access
Short Communication 19 May 2023
Subclinical Paroxystic Atrial Fibrillation after Stroke
Stroke is a pathology with great social repercussion, since it is the second cause of mortality in the world and the first cause of dependency in adults [1].…
551 Views 82 Downloads
Open Access
Review Article 30 Mar 2023
Relationship between Ischemic Stroke and Atrial Fibrillation, Systematic Review
Introduction: Atrial Fibrillation (AF) is not only one of the main causes of stroke, but it is also the most common sustained cardiac arrhythmia. As a result of population aging, an increase in the prevalence of AF and o…
435 Views 94 Downloads
Open Access
Review Article 29 Mar 2023
Ischemic Stroke of Cardioembolic Origin Systematic Review
Ischemic stroke corresponds to 80% of cases in Brazil, which demonstrates the epidemiological importance in Brazil. The magnitude of this fact reflects the reason why stroke is considered the second cause of death in the…
1,018 Views 89 Downloads
Open Access
Review Article 19 Jan 2023
ET-traps: A Potential Therapeutic for Use in Human Complications of the Heart and Kidneys
Endothelin-1 (ET-1) is a potent bioactive mediator that induces vasoconstriction and promotes vascular remodeling. Previous studies indicate that ET-1 plays an important role in the pathophysiology of humans. This includ…
1,537 Views 94 Downloads
Open Access
Rapid Communication 05 Jan 2023
ASSUMER on PYP Scan for Cardiac Amyloid Typing and Origin: Case-Specific Corroborating Clinical Background and Genetic Analysis
Suspicion for Cardiac Amyloidosis (CA) led a 75-year-old male patient with fatigue, dyspnea, and palpitations to be subjected to scintigraphic myocardial investigation with technetium-99m-pyrophosphate (99mTc-PYP, or PYP…
799 Views 98 Downloads
Open Access
Mini Review 04 Jan 2023
Molecular Imaging in Oncocardiology
Cancer and Cardiovascular Disease (CVD) are the most common causes of death and disability in many countries. Cancer and CVD are closely related in terms of both scientific and clinical perspectives. Oncocardiology has r…
560 Views 110 Downloads
Open Access
Case Report 28 Nov 2022
Cancer Patient was attacked by Thrombosis: Case Report
Background: Cancer is the second leading cause of mortality after cardiovascular disease. The second common leading cause of mortality in cancer patients is thrombosis, vary from arterial or venous thromboembolism to dis…
763 Views 79 Downloads
Open Access
Case Report 28 Nov 2022
Successful 4-Year Outcome Following Convergent Ablation for Longstanding Persistent Atrial Fibrillation in an Octogenarian – Novel Therapy for an Old Condition in the Very Elderly
The most common age range for Atrial Fibrillation (AF) prevalence over the coming decades will potentially be in those over 75 years old. However, despite widespread recognition of the strong association between AF burde…
764 Views 70 Downloads
Open Access
Research Article 28 Nov 2022
Effects of the Mechanism of Traditional Chinese Medical Prescription-Yiqihuoxue Formula on Vasculopathy with Systemic Sclerosis
Vasculopathy is a prevalent complication that may appear in the early stage of Systemic Sclerosis (SSc). Traditional Chinese medical prescription-Yiqihuoxue formula (YQHX) has been used as a therapeutic option for SSc in…
1,304 Views 83 Downloads
Open Access
Opinion 22 Nov 2022
Budd-Chiari Syndrome: From Clinical to Ultrasonic Diagnosis
Budd-Chiari Syndrome (BCS) is a rare but specific vascular disease. However, the first symptoms of BCS in clinical can be various, such as abdominal pain, lower limb swelling, liver enlargement, etc. BCS is easily misdia…
1,086 Views 78 Downloads
Open Access
Research Article 27 Oct 2022
Research Progress on the Correlation between Hyperhomocysteinemia and Arteriosclerosis Obliteran
Arteriosclerosis Obliteran (ASO) is a local manifestation of systemic arteriosclerosis in the lower extremity arteries. ASO is a chronic progressive disease caused by arteriosclerosis, such as intimal thickening, lumen s…
1,543 Views 78 Downloads 1 Citation