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Granulomatous Amebic Encephalitis Caused by Entamoeba Dispar

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Open Access
Article Type Review Article
Subject Biology Group
OCLC JBRES Record
Weiwei Qi, Junjie Guo and XueXu*
Issue: Volume6-Issue7
Pages: 858-861
Received: 2025-06-25
Accepted: 2025-07-01
Published: 2025-07-02

Abstract

Entamoeba dispar, belonging to the Genus Entamoeba along with Entamoeba histolytica that causes amebiasis, was previously considered a non-pathogenic ameba and an ideal model for studying the pathogenesis of amebiasis. However, since its strains were isolated from symptomatic patients in Brazil in 1996, its pathogenic potential has been a subject of discussion. We report a case of multiple granulomatous encephalitis in a 4-year-old immunocompetent boy presenting with left eye esotropia. Sequences of E. dispar were detected in his cerebrospinal fluid through Next-Generation Sequencing (NGS). After three courses of metronidazole therapy, the brain and lung lesions showed significant reduction in subsequent examinations. This case expands the spectrum of diseases associated with E. dispar.

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© 2025 Santos Federico OR, et al., Distributed under Creative Commons CC-BY 4.0 Creative CommonsAttribution

How to cite this article

Qi W, Guo J, Xu X. Granulomatous Amebic Encephalitis Caused by Entamoeba Dispar. J Biomed Res Environ Sci. 2025 Jul 01; 6(7): 858-861. doi: 10.37871/jbres2138, Article ID: JBRES2138, Available at: https://www.jelsciences. com/articles/jbres2138.pdf

Subject area(s)

ParasitologyBiology

References

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