Kevin Roe*
Volume5-Issue6
Dates: Received: 2024-06-11 | Accepted: 2024-06-12 | Published: 2024-06-14
Pages: 584-587
Abstract
A return to the climate of the middle Pliocene is probable within this century and the increased temperatures, particularly at higher latitudes, will boost the spread of several bacterial, viral and protozoan parasite pathogens which cause severe and/or lethal diseases. The warmer climate effects on the spread and evolution of some fungal pathogens may also increase their virulence, although probable, this is less certain. The increase in the range and pathogen populations in the various hosts and vectors during a return to the middle Pliocene epoch will also increase the probability that several pathogens will evolve more immuno-evasive genetic strains which will be more dangerous for humans and animals. There could also be severe impacts on livestock and agricultural food chains.
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DOI: 10.37871/jbres1930
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© 2024 Roe K. Distributed under Creative Commons CC-BY 4.0 
How to cite this article
Roe K. Return to a Warmer Climate of the Middle Pliocene will Boost Bacterial, Viral and Protozoan Parasite Pathogen Induced Diseases. J Biomed Res Environ Sci. 2024 Jun 14; 5(6): 584-587. doi: 10.37871/jbres1930, Article ID: JBRES1930, Available at: https://www.jelsciences.com/articles/jbres1930.pdf
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References
- Robinson MM, Dowsett HJ, Chandler MA. Pliocene Role in assessing future climate impacts. Eos Trans. 2008;89(49):501-502. doi: 10.1029/2008EO490001.
- Kaur H, Lynn AM. Mapping the FtsQBL divisome components in bacterial NTD pathogens as potential drug targets. Front Genet. 2023 Jan 4;13:1010870. doi: 10.3389/fgene.2022.1010870. PMID: 36685953; PMCID: PMC9846249.
- Roe K. Pathogen regulatory RNA usage enables chronic infections, T-cell exhaustion and accelerated T-cell exhaustion. Mol Cell Biochem. 2023 Nov;478(11):2505-2516. doi: 10.1007/s11010-023-04680-9. Epub 2023 Mar 21. PMID: 36941498; PMCID: PMC10027582.
- Henriquez-Figuereo A, Morán-Serradilla C, Angulo-Elizari E, Sanmartín C, Plano D. Small molecules containing chalcogen elements (S, Se, Te) as new warhead to fight neglected tropical diseases. Eur J Med Chem. 2023 Jan 15;246:115002. doi: 10.1016/j.ejmech.2022.115002. Epub 2022 Dec 5. PMID: 36493616.
- Pérez-Molina JA, Molina I. Chagas disease. Lancet. 2018 Jan 6;391(10115):82-94. doi: 10.1016/S0140-6736(17)31612-4. Epub 2017 Jun 30. PMID: 28673423.
- Bhattacharjee S, Ghosh D, Saha R, Sarkar R, Kumar S, Khokhar M, Pandey RK. Mechanism of Immune Evasion in Mosquito-Borne Diseases. Pathogens. 2023 Apr 23;12(5):635. doi: 10.3390/pathogens12050635. PMID: 37242305; PMCID: PMC10222277.
- Leggewie M, Scherer C, Altinli M, Gestuveo RJ, Sreenu VB, Fuss J, Vazeille M, Mousson L, Badusche M, Kohl A, Failloux AB, Schnettler E. The Aedes aegypti RNA interference response against Zika virus in the context of co-infection with dengue and chikungunya viruses. PLoS Negl Trop Dis. 2023 Jul 13;17(7):e0011456. doi: 10.1371/journal.pntd.0011456. PMID: 37440582; PMCID: PMC10343070.
- Fay RL, Ngo KA, Kuo L, Willsey GG, Kramer LD, Ciota AT. Experimental Evolution of West Nile Virus at Higher Temperatures Facilitates Broad Adaptation and Increased Genetic Diversity. Viruses. 2021 Sep 22;13(10):1889. doi: 10.3390/v13101889. PMID: 34696323; PMCID: PMC8540194.
- Liu Z, Zhang Q, Li L, He J, Guo J, Wang Z, Huang Y, Xi Z, Yuan F, Li Y, Li T. The effect of temperature on dengue virus transmission by Aedes mosquitoes. Front Cell Infect Microbiol. 2023 Sep 21;13:1242173. doi: 10.3389/fcimb.2023.1242173. Erratum in: Front Cell Infect Microbiol. 2023 Oct 24;13:1320461. PMID: 37808907; PMCID: PMC10552155.
- Xue X, Deng H, Zhao L, Zang X, Asuquo IP, Meng M, Ma X, Qin C, Meng Y, Wu C, Gao J, Pan L. Cryptococcosis caused by cryptococcus gattii: 2 case reports and literature review. Medicine (Baltimore). 2020 Dec 11;99(50):e23213. doi: 10.1097/MD.0000000000023213. PMID: 33327239; PMCID: PMC7738107.
- Salzer HJF, Burchard G, Cornely OA, Lange C, Rolling T, Schmiedel S, Libman M, Capone D, Le T, Dalcolmo MP, Heyckendorf J. Diagnosis and Management of Systemic Endemic Mycoses Causing Pulmonary Disease. Respiration. 2018;96(3):283-301. doi: 10.1159/000489501. Epub 2018 Jun 28. PMID: 29953992.
- Roe K. Treatment alternatives for multidrug-resistant fungal pathogens. Drug Discov Today. 2023 Jun;28(6):103596. doi: 10.1016/j.drudis.2023.103596. Epub 2023 Apr 20. PMID: 37086779.
