Macronutrient fluxes from diffuse sources can affect aquatic ecosystems' health and drinking water quality. These are critical issues covered in the sixth gal of the 2030 Agenda for Sustainable Development to ensure the availability and sustainable management of water and sanitation for all [1]. To promote water quality protection, we need a better understanding of the hydrogeochemical, ecological and anthropogenic factors affecting diffuse pollution by Nitrogen (N) and Phosphorus (P) compounds generated by human activities.