All Articles

This study documents the stepwise development and evaluation of a generic Lymecycline 408 mg hard gelatin capsule manufactured locally in Pakistan. The formulation process began with the selection of suitable pharmacopeial excipients after conducting accelerated compatibility testing to ensure that no undesirable physi…

Background: The Nucleotide-binding oligomerization domain-Like Receptor family CARD domain-containing 4 (NLRC4) inflammasome is a critical component of innate immunity. As an intracellular pattern recognition receptor, NLRC4 contributes to host defence by responding to diverse microbial ligands through interactions wit…

Background: Acute Kidney Injury (AKI) is a serious complication after cardiac surgery. We sought to determine the possible onset of AKI in patients undergoing cardiac surgery with different cardioplegic solution during Cardiopulmonary Bypass (CPB) including Custodiol Solution (CS), cold crystalloid St. Thomas cardiople…

Music, deeply embedded in human culture, profoundly influences physiological and psychological states, showcasing remarkable potential within clinical environments, notably the catheterization laboratory (Cath Lab). This article offers an in-depth examination of music's crucial role in interventional cardiology from bo…

Bilharzias is Schistosomiasis is prevalent in tropical and subtropical countries such as Yemen. Urogenital schistosomiasis can cause infertility in both males and females. Severe schistosomiasis can cause intense granulomatous epididymitis and inhibition of spermatogenesis, causing male factor infertility. This study r…

Introduction: Rising divorce rates globally represent a significant social concern. Among many reasons, the most important are poor communication, accounting for 38% of divorces, while sexual dissatisfaction represents a very high critical contributing factor.Aim: We examined the role of emotional and physical intimacy…

Premalignant hematology patients categorized as monoclonal B-cell lymphocytosis, clonal cytopenia of indeterminate importance, monoclonal gammopathy of unknown relevance, and clonal hematopoiesis. These disorders are categorized as premalignant due to their clonal proliferation of myeloid, lymphoid, or plasma cells, wi…

Objective: To evaluate serum parameters in treatment-naive and treated Primary Open Angle Glaucoma (POAG), and no glaucoma eye patients. Methods: Fasting blood samples of the participants were analyzed for electrolytes, proteins, urea, Blood Urea Nitrogen (BUN), creatinine, lipids, and liver enzymes. Results: Electroly…

The article, which raises never-before-bioethical and legal questions, is a consideration of the manner in which rapid advances in neurotechnology are reshaping criminal law. Neurotechnology is changing how we think about free will, criminal intent, and personal responsibility. This also includes devices that observe o…

This phenomenological study utilized a qualitative research design which aimed to understand the experiences of the Doctors to The Barrio (DTTB) working in Geographically Isolated and Disadvantaged Areas (GIDA). In this study, nine (9) DTTB were chosen as participants through purposive sampling technique. Each underwen…

Background: Many chronic conditions that frequently cause pain in certain areas of the body seem to be related to the infiltration of unwanted irritants across a mucosal barrier in certain tissues that have been weakened by genetic, traumatic, or infection factors. They all have in common that they are ameliorated foll…

Although the literature on the spatial dimension of social inequality in Attica and on mortality trends in Greece is extensive, studies investigating the spatial variation in life expectancy at birth and at age 65 within the Region of Attica are rare. The primary purpose of this paper is to examine whether there is spa…