All Articles

Background: Cancer affects patients far beyond the physical burden of disease. Emotional distress, uncertainty, existential suffering, and unmet spiritual needs frequently accompany diagnosis, treatment, survivorship, and end-of-life care. In Ayurveda, Daivavyapashraya Chikitsa refers to spiritually oriented measures s…

Although the effects of institutional quality and its indicators on economic growth have been extensively examined, studies focusing on the institutional quality-financial sector development link remain limited. Therefore, this study concentrates on the institutional quality-financial development link, while also incor…

Chronic Urticaria (CU) poses a significant therapeutic challenge, as conventional antihistamines are ineffective for about 40% of patients. This treatment gap is linked to key pathological drivers: impaired histamine metabolism due to low Diamine Oxidase (DAO) activity, immune dysregulation, and vitamin D deficiency. A…

The global resurgence of syphilis has coincided with increasing evidence of complex interactions between Treponema pallidum infection and neurological disorders, extending beyond classical neurosyphilis manifestations. This perspective article synthesizes recent clinical and translational evidence on syphilis-associate…

Randomised Controlled Trials (RCTs), particularly those utilising a Double-Blind (DBRCT) design, are the gold standard in medical research. However, applying this model to dietary interventions-especially Plant-Based Diets (PBDs)-poses considerable methodological and ethical challenges. The inability to blind participa…

Artificial intelligence (AI) is increasingly shaping genome-editing design, supporting predictive modeling of TALEN- and CRISPR-based systems by integrating genomic sequence features, chromatin structural context, and experimental metadata. However, the rapid proliferation of machine learning (ML)-driven tools has crea…

We understand the surface roughness and the vertical height features of polymers using surface profilometer. We study 5 polymers that include polystyrene, transparent Polyethylene Oxide (PEO), translucent Polyethylene Oxide, Polyvinyl Chloride (PVC) and textile cloth polymers for the first time. We study the front and …

Background: The lower Taedong River (DPR Korea) is a typical fluvial-estuarine-marine composite sedimentary zone characterized by strong heterogeneity, complex hydrodynamics, and highly variable sediment properties. These geological and hydrological conditions give rise to severe drilling challenges, including unstable…

Monoclonal antibody therapy directed against certain pathways leading to the eventual cellular immune reaction to an irritating agent has been a mainstay of therapy for many pathological conditions considered autoimmune in nature. Unfortunately, these monoclonal antibody therapies are extremely expensive, and may lead …

Background: Caseous Lymphadenitis (CL) is a chronic infectious and contagious disease that affects sheep and small ruminants, whose prevalence in Argentine Patagonia has been demonstrated over the years. However, this disease continues to be underestimated within the sheep farming sector, causing economic losses due to…

Background: Degenerative Knee Osteoarthritis (KOA) is a major cause of pain and disability, and effective joint-preserving therapies for moderate (Kellgren-Lawrence [KL] grade 2-3) disease remain limited. Bone Marrow Aspirate Concentrate (BMAC) has emerged as a regenerative treatment option, and intra-articular BMAC in…

Objective: To evaluate the phytochemical composition of Guiera senegalensis leaf extracts using GC–MS and to molecularly characterize clinical isolates of Escherichia coli and Staphylococcus aureus.Methods: Leaf extracts were prepared using aqueous and ethanol solvents. Phytochemical constituents were qualitatively and…

Background: Takayasu arteritis, rheumatoid arthritis, and autoimmune hypothyroidism are immune-mediated disorders that rarely coexist in a single patient. Their concurrence represents an important example of polyautoimmunity and may create diagnostic and therapeutic challenges.Case presentation: A 45-year-old Sudanese …

Background: Poliomyelitis, also known as infantile paralysis, is an infectious disease caused by the poliovirus, which may present with a broad clinical spectrum ranging from mild, self-limited symptoms to severe neurological impairment, including paralysis of limb and respiratory muscles. Although currently rare due t…

Background: Abdominal obesity is a major driver of metabolic dysfunction, yet conventional screening methods fail to capture dynamic glycemic abnormalities. CGM-based phenotyping in non-diabetic, centrally obese Southeast Asian populations remains unexplored.Objective: To identify glucose phenotypes (glucotypes) using …