Infectious Diseases & Immune System Research
Section Editors
Research Topics in this Section
Allergy
Blood Disorders
22
Blood DisordersThese topics are filtered from our journals helping to discover the community within the widespread of multi-discip…
Hematology
20
HematologyThese topics are filtered from our journals helping to discover the community within the widespread of multi-disciplinar…
HIV/AIDS
5
HIV/AIDSThese topics are filtered from our journals helping to discover the community within the widespread of multi-disciplinary …
Immunology
30
ImmunologyThese topics are filtered from our journals helping to discover the community within the widespread of multi-disciplinar…
Infectious Diseases
38
Infectious DiseasesThese topics are filtered from our journals helping to discover the community within the widespread of multi-di…
Vaccines
9
Aim: Vaccines are agents that trigger an immune response from our bodies to better equip them for dealing with a diseases. Scope:T…
Recent Articles
50 articles
Open Access
Review Article 22 Apr 2026
Therapeutic Strategies in Acute Myeloid Leukemia: Current Advances and Future Directions
Acute Myeloid Leukemia (AML) is a clinically aggressive and molecularly heterogeneous hematologic malignancy characterized by poor long-term outcomes, largely due to high rates of relapse and therapeutic resistance. For …
15 Views 56 Downloads
Open Access
Case Report 31 Mar 2026
Combined Dopaminergic Drugs to Treat Pyoderma Gangrenosum
Monoclonal antibody therapy directed against certain pathways leading to the eventual cellular immune reaction to an irritating agent has been a mainstay of therapy for many pathological conditions considered autoimmune …
9 Views 51 Downloads
Open Access
Review Article 28 Jan 2026
Systemic Lupus Erythematosus: Clinical, Diagnostic, and Therapeutic Perspectives
Background: Systemic Lupus Erythematosus is a chronic autoimmune disease with systemic involvement, predominantly affecting women of reproductive age. Its development is related to genetic, hormonal, and environmental fa…
32 Views 97 Downloads
Open Access
Review Article 20 Jan 2026
Anthrax Pathogenesis as Overcoming Lymph Node Macrophage Barrier
125 Views 76 Downloads
Open Access
Research Article 30 Dec 2025
Detoxification and Characterization of an Alpha Nanotoxoid of Clostridium septicum In vitro and In vivo
One solution to eliminate toxins is to trap them in polymer nanoparticles. Alpha clostridial toxins typically form pores in the cell membrane, allowing them to enter cells and exert their destructive and deadly effects. …
150 Views 79 Downloads
Open Access
Research Article 13 Dec 2025
Zoonotic Pathogens Anaplasma phagocytophilum, Babesia microti, Babesia odocoilei, and Borrelia burgdorferi Sensu Lato Detected in Ixodes scapularis Ticks Collected at an Established Population in Eastern Canada
Tick-borne zoonotic diseases baffle clinicians and traumatize patients worldwide. We provide the first documentation of four different tick-borne zoonotic pathogens in an established population of blacklegged ticks, Ixod…
61 Views 117 Downloads 1 Citation
Open Access
Review Article 08 Nov 2025
Exploring the Tumor Microenvironment: Macrophages and PD-1 Checkpoint Inhibitors
This review provides an in-depth examination of the tumor microenvironment, macrophages, and PD-1 checkpoint inhibitors. It delves into the fundamental aspects of the tumor microenvironment and macrophages, discussing th…
446 Views 75 Downloads
Open Access
Review Article 05 Nov 2025
The Cellular Crosstalk between the Endothelial Cells and Immune Cells in the Metastasis of NSCLC
Background: Bone and brain metastasis are common in the NSCLC, and tumor environment has played a vital role in the metastasis, endothelial cells are a key component of the tumor microenvironment and its role in the deve…
189 Views 73 Downloads
Open Access
Comparative Studies 21 Oct 2025
The Correlation between the Efficacy and Survival of Chemotherapy Combined with PD-1 and Granulocyte Colony-Stimulating Factor in Patients with Advanced NSCLC
Objective: This study investigates the relationship between the prophylactic use of granulocyte colony-stimulating factors and clinical efficacy, as well as survival outcomes, in patients with advanced non-small cell lun…
205 Views 82 Downloads
Open Access
Descriptive Research 14 Aug 2025
HMPV in Focus: Emerging Insights into a Silent Respiratory Threat
Human Metapneumovirus (HMPV) is a major cause of respiratory illness, primarily affecting young children, and can also cause severe disease in elderly or immunocompromised adults. Although first identified in 2001, retro…
17 Views 75 Downloads 1 Citation
Open Access
Review Article 30 Jun 2025
Dynamics of Leukemia Models
Millions of people are affected by leukemia. It is important to understand the progression dynamics of this disease to be able to minimize the damage that is caused by it. This article provides a mathematical framework …
220 Views 76 Downloads
Open Access
Original Article 23 Jun 2025
Age and Disease activity related Biomarkers in Takayasuarteritis: Comparison with Giant Cell Arteritis
Background and objective: Measuring Takayasu (TAK) disease activity remains a difficult task. The aims of this study were to identify biomarkers reflecting disease activity in TAK, to analyze the effects of treatment, to…
342 Views 82 Downloads
Open Access
Review Article 16 Jun 2025
Effectiveness of ALPHABAN 40 WP (Cypermethrin) insecticide in Blattella germanica and Aedes aegypti control in Cuba
Disease vector control in Cuba is carried out primarily with chemical insecticides, with those based on cypermethrin being the most commonly used .In Cuba there are 30 registered formulations whose active ingredient is t…
1,281 Views 80 Downloads
Open Access
Research Article 28 Mar 2025
Potential Use of Immunological Indices as Predictors of Bacterial Infections Following Cardiopulmonary Bypass Surgery in Elderly Patients
Cardiac surgery with Cardiopulmonary Bypass (CPB) induces postoperative immunological responses in patients. We aimed to determine changes in various immunological parameters in patients during and after cardiac surgery …
260 Views 140 Downloads 1 Citation
Open Access
Mini Review 28 Feb 2025
Advances in Personalized Medicine Personalized Neoantigen Vaccines and Immune Checkpoint Inhibitor Combination Treatments
Background: Solid tumor malignancies are a cause of mortality in adults, with growing prevalence in young adults. Chemotherapies in combination with immune checkpoint inhibitors have been shown to induce responses in the…
1,400 Views 102 Downloads
Open Access
Case Study 31 Jan 2025
Detection of an Imported Case of Severe Crimean-Congo Hemorrhagic Fever in a Patient with Comorbidities, Dakar, Senegal 2023
In July 2023, a diabetic from Mauritania was diagnosed as a severe case of Crimean-Congo hemorrhagic fever (CCHF) at Dakar hospital, Senegal. The phylogenetic analysis revealed the new strain as a CCHF virus reassortant …
594 Views 121 Downloads 2 Citations
Open Access
Case Report 31 Jan 2025
Bordetella bronchiseptica Infection in an Immunocompetent Adult and a Literature Review on this Rare Zoonosis
Introduction: Bordetella bronchiseptica, a Gram-negative coccobacillus, studied for its role in Canine Infectious Respiratory Disease and porcine atrophic rhinitis. It is an opportunistic pathogen with few reported cases…
2,224 Views 110 Downloads
Open Access
Opinion 10 Jan 2025
Human Metapneumovirus (hMPV): A Call to Action for Research in Infectious Diseases and Immunology
421 Views 135 Downloads
Open Access
Short Communication 25 Nov 2024
Potato Derived Exosome Nanoparticles as Anti Inflammation Agents
The screening of exosomes from various sources reveals that potato-derived exosomes exhibit the most significant anti-inflammatory activity, as demonstrated by RT-PCR analyses of Tumor Necrosis Factor expression in exoso…
698 Views 127 Downloads 2 Citations
Open Access
Review Article 10 Nov 2024
A Comprehensive Review of IgG4 Related Disease Unraveling the Role of B and T Lymphocytes in the Pathogenesis of the Disease
IgG4-RD is a chronic fibro inflammatory disease characterized by a significant elevation of serum IgG4 concentration and marked infiltration of IgG4-positive plasma cells in the affected organs. A dense lymphoplasmacytic…
6,673 Views 119 Downloads
Open Access
Review Article 10 Nov 2024
Microbiome-Targeted Therapies: Developments and Recent Updates
The microbiome, a complex microbial community found in ecosystems like animals, plants, and humans, plays a crucial role in maintaining health and preventing diseases. These communities promote healthy growth, protect ag…
3,463 Views 109 Downloads
Open Access
Descriptive Research 25 Oct 2024
Application of UV-C Technology in Managing the Monkeypox Epidemic: Surface, Air, and PPE Decontamination
The outbreak of monkeypox, a zoonotic viral disease, necessitates effective strategies for infection control and decontamination. Ultraviolet-C (UV-C) radiation, with its germicidal properties, has long been utilized for…
640 Views 115 Downloads 1 Citation
Open Access
Research Article 22 Oct 2024
Molecular Detection of Borrelia burgdorferi sensu lato, Borrelia miyamotoi, Babesia odocoilei, Babesia microti and Anaplasma phagocytophilum in Ixodes Ticks Collected across Canada
Tick-borne zoonotic diseases are a profound challenge to healthcare practitioners, and an overwhelming scourge to patients worldwide. On the whole, patients have great difficulty getting diagnosed and treated, and often …
698 Views 110 Downloads 1 Citation
Open Access
Review Article 17 Oct 2024
The Fear Avoidance Scale of the Sickler
Background: Fear, one of the psychosocial parameters, has received much attention lately. Based on previous work done elsewhere in other disease states, we sought to investigate the fear – avoidance model, biofeedback …
194 Views 110 Downloads
Open Access
Research Article 27 Sep 2024
Populations of Triple Negative and Hormone Receptor Positive HER2 Negative Breast Tumors Share Immune Gene Profiles
Background: Immune therapy has revolutionized the treatment of certain cancers including melanoma and lung cancer. Breast cancer has fewer tumors with high immune infiltrate and Immune Checkpoint Inhibitor (ICI) therapy…
218 Views 116 Downloads
Open Access
Research Article 20 Sep 2024
Occult Hepatitis C Infection in Kidney Transplant and Hemodialysis Patients Identified five to Eight Years after Sustained Virological Response
Background: Occult Hepatitis C Infection (OCI) is characterized by the detection of Hepatitis C Virus (HCV) RNA in hepatocytes and in Peripheral Blood Mononuclear Cells (PBMCs) with no detection in serum, and PBMCs and R…
325 Views 107 Downloads
Open Access
Case Report 31 Aug 2024
Spontaneous Breast Hematoma Induced by Vitamin K Antagonist Therapy: A Case Report
Anticoagulant medications, particularly Vitamin K Antagonists (VKAs), are essential for managing thrombotic conditions but can cause severe side effects such as spontaneous hematomas. This case report describes a 69-year…
624 Views 103 Downloads
Open Access
Case Report 24 Jul 2024
Donor vs. Donor or Recipient vs. Recipient? A Singular Case of Post Hematopoietic Stem Cell Transplantation Autoimmune Hemolytic Anemia in a Pediatric Patient
Hematopoietic Stem Cell Transplantation (HSCT) is a curative treatment for certain blood disorders, but can lead to complications such as Autoimmune Cytopenia (AIC), particularly Autoimmune Hemolytic Anemia (AIHA). AIHA …
214 Views 116 Downloads
Open Access
Case Report 24 Jul 2024
Postural Orthostatic Tachycardia Syndrome (POTS) of Autoimmune Origin - Case and Review
Introduction: Postural Orthostatic Tachycardia Syndrome (POTS) belongs to a group of orthostatic intolerance syndromes. It is defined by the increase in heart rate ≥30 bpm or heart rate higher than 120/min during first…
3,063 Views 116 Downloads 1 Citation
Open Access
Short Communication 14 Jun 2024
Return to a Warmer Climate of the Middle Pliocene will Boost Bacterial, Viral and Protozoan Parasite Pathogen Induced Diseases
A return to the climate of the middle Pliocene is probable within this century and the increased temperatures, particularly at higher latitudes, will boost the spread of several bacterial, viral and protozoan parasite pa…
377 Views 100 Downloads
Open Access
Editorial 08 Jun 2024
The Promise of Tumor Mutation Burden and Microenvironment as Biomarkers in Glioma Treatment
Gliomas, particularly high-grade gliomas like glioblastomas, represent some of the most formidable challenges in oncology. These brain tumors are notorious for their resistance to conventional therapies, including surger…
410 Views 103 Downloads
Open Access
Case Report 05 Jun 2024
Elbow Bursitis, Spondylodiscitis and Meningitis Due to Streptococcus agalactiae: A Case Report
The incidence of S.agalactiae infection in older adults is increasing, especially in those with comorbidities. During the last four decades, invasive infections in adults unrelated to pregnancy have been increasingly rep…
316 Views 60 Downloads
Open Access
Research Article 23 May 2024
Serological Diagnosis and Molecular Detection of Varicella Zoster Virus in Patients with Suspected Meningoencephalitis
Background: Primary infection (chickenpox) or infection after reactivation (herpes zoster) of the herpesvirus Varicella-Zoster Virus (VZV) can lead to central nervous system complications, such as meningoencephalitis. Th…
344 Views 134 Downloads
Open Access
Brief Report 05 Apr 2024
The Recombinant NS3 Protein a Potential Antigen for Dengue Vaccine Development
The NS3 protein is a multifunctional non-structural protein involved in dengue virus polyprotein processing. This protein is also target in the immune response against dengue virus infection. The predominance of cytotoxi…
1,428 Views 111 Downloads
Open Access
Original Article 03 Feb 2024
One-Year Investigation of Hepatitis A Virus and Rotavirus in Two Waste Water Treatment Plants in Egypt
Background: Waterborne enteric viruses are evolving source of disease outbreaks and represent a major threat to global public health. The repetitive assessment of water environments is necessary to manage enteric virus…
1,555 Views 142 Downloads
Open Access
Mini Review 09 Jan 2024
From Healthcare-Associated Bacterial Infection to Building Design
SARS-CoV-2 showed how measures against airborne pathogens are critical in clinical environments. Bacteria make no exception. Healthcare-associated or Hospital-Acquired Infections (HAIs) represent one of the major concern…
530 Views 159 Downloads
Open Access
Review Article 20 Dec 2023
Strategies for Improving Adherence in Patients with HIVAIDS
Human Immunodeficiency Virus (HIV)-1 is the cause of Acquired Immunodeficiency Syndrome (AIDS). Due to advances in clinical management, HIV/AIDS is now regarded a chronic disease instead of terminal disease. However, non…
1,680 Views 85 Downloads
Open Access
Mini Review 12 Dec 2023
Interaction between Chronic Influenza and COVID-19: Novel Aspects of Immune System Combat
This abstract provides an overview of two highly contagious viruses - influenza viruses and the COVID-19 virus, causing severe acute respiratory illness. The paper examines common and unique characteristics of the viruse…
2,766 Views 111 Downloads
Open Access
Case Study 24 Nov 2023
A Case of Holothuroidea-like Erythrocytes
Ektacytometric examination of red blood cells with morphological anomaly is presented. Confocal microscopy of the blood from the patient N. shows the abundance of RBCs in the form of representatives of the Holothuroidea.…
722 Views 93 Downloads
Open Access
Case Report 23 Nov 2023
Chronic Myeloid Leukemia (CML) with Permanent Hearing Loss
Objective: The present case study aims to discuss a rare case of chronic myeloid leukemia causing bilateral hearing impairment, tinnitus, and vertigo.Introduction: Chronic Myeloid Leukemia (CML) or chronic granulocytic l…
934 Views 126 Downloads 1 Citation
Open Access
Review Article 31 Oct 2023
Review on Pest Des Petits Ruminants Virus and its Socioeconomic Impact in Small Ruminants
Peste Des Petits Ruminants (PPR) are a highly contagious viral disease that mainly affects sheep and goats. It belongs to the genus Morbillivirus in the family Paramyxoviridae. Today, this disease is considered a cause o…
2,853 Views 137 Downloads 3 Citations
Open Access
Original Article 29 Aug 2023
Hemogram Response to Vasoclusive Crisis in Sickle Cell Patients in Enugu, South East, Nigeria
Vasoclusion crisis is a major cause of morbidity and mortality in patients with Sickle Cell Anemia (SCA). There are currently a paucity of data on the hemogram response to vasoclusive crisis in patients with SCA in the E…
836 Views 99 Downloads
Open Access
Original Article 26 Apr 2023
Research Progress on Anti-Tumor Mechanism of Tannins in Traditional Chinese Medicine
By reviewing the literature on the efficacy of tannins in traditional Chinese medicine in the last decade or so, we have classified the anti-tumor mechanism of tannins in conjunction with the latest mechanism exploration…
1,850 Views 95 Downloads 3 Citations
Open Access
Research Article 16 Mar 2023
Fungal Infection and Mycotoxins Contamination on Farm-Stored Chickpea in Major Producing Districts of Ethiopia
Crop susceptibility to moisture content, quality of storage facilities in the farm contributes to fungal infections and mycotoxin contamination. Chickpea grain loss in many parts of the world has been due to inadequate a…
2,097 Views 49 Downloads 2 Citations
Open Access
Observational Studies 09 Feb 2023
A Presentation of Analyses of COVID-19 Vaccine Samples, Blood Samples, Urine Samples, Foot Bath Samples, Sitz Bath Samples, and Skin-Extract Samples
Some members of Korea Veritas Doctors of COVID-19 analyzed COVID-19 vaccines samples, blood samples, urine samples, foot bath samples, sitz bath samples, and skin extract samples from COVID-19 vaccinated and unvaccinated…
7,266 Views 261 Downloads 1 Citation
Open Access
Original Article 26 Jan 2023
The Effect of Montelukast in Children with Asthma Predictive Index Negative Episodic Viral Wheezing
Background: The effectiveness of montelukast for wheezing in young children is not clear. We aimed to evaluate whether the use of montelukast in the treatment of wheezing affects the number of attacks in children aged 1 …
1,359 Views 100 Downloads
Open Access
Descriptive Research 24 Jan 2023
Do COVID-19 RNA-Injections Affect Male Fertility? Latest Facts and Perspective
Background: Based on available data on male fertility adverse effects after COVID-19 injections, we draw the reader´s attention to open questions and undeniable risks of the new RNA-based vaccine technology.Methods: Rev…
7,497 Views 223 Downloads
Open Access
Mini Review 12 Dec 2022
Regulation of Amino Acid Metabolism in Hematological Malignancies: Advances from Transcriptomics and Metabolomics
Tumor cells use amino acids to rewire metabolic pathways to meet increased demands for energy, reducing equivalents, and cellular biosynthesis. Aside acting as building blocks for protein synthesis, amino acids also func…
807 Views 79 Downloads
Open Access
Research Article 05 Dec 2022
Molecular Detection of Anaplasma phagocytophilum, Babesia odocoilei, Babesia species and Borrelia burgdorferi Sensu Lato in Songbirds
The blacklegged tick, Ixodes scapularis, is known to carry various tick-borne zoonotic pathogens with the potential to cause debilitating human and animal diseases. Juvenile I. scapularis parasitize songbirds and, perhap…
1,075 Views 66 Downloads 4 Citations
Open Access
Research Article 30 Nov 2022
What Role Do Immunological and Inflammatory Biomarkers Play on Mortality and Exacerbations in COPD Patients?
Background: COPD phenotypes have been identified according to patient clinical characteristics and, more recently, to their immunological markers. However, the role of these biomarkers in relation to exacerbations in dif…
693 Views 97 Downloads