Fractional Calculus (FC) has emerged as a valuable tool in various fields. This study explores the historical development of (FC) and examines prominent definitions regarding Fractional Derivatives (FD), such as the Riemann-Liouville, Grunwald-Letnikov, Caputo Fractional Derivative, Katugampula derivatives, Caputo Fractional Derivative, Caputo-Fabrizio Fractional Derivative and as well as Atangana-Baleanu Fractional Derivative. It critically evaluates their strengths, weaknesses and implications on (FD) equations. The findings contribute to establishing a clearer understanding of Fractional Derivatives (FD) and guiding their appropriate use in practical scenarios. It investigates the impact of different definitions on the properties and behaviors of (FD), providing valuable insights for researchers.