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Home/ All Articles/ Vaccination with either mRNA or Vector-Based COVID-19 Vaccine has no Detectable Effect on …

Abstract & Article Details

Research Article • Vol.3, Issue 9 • ISSN: 2766-2276 • Open Access • CC BY 4.0

Open Access Research Article Vol.3, Issue 9 September 22, 2022

Vaccination with either mRNA or Vector-Based COVID-19 Vaccine has no Detectable Effect on Sperm Parameters

DOI: 10.37871/jbres1558
Authors
Philippos Edimiris*, Cornelius Doehmen, Lisa Mueller, Marcel Andree, Dunja Maria Baston-Buest, Sebastian Buest, Ortwin Adams, Jan-Steffen Kruessel and Alexandra Petra Bielfeld
Full Text PDF

Abstract

Background: With the introduction of COVID-19 vaccines in 2021, concerns arose regarding their impact on male fertility. Therefore, this study investigated the effect of mRNA- and vector-based COVID-19 vaccination on male fertility by analyzing sperm parameters in subjects with unrestricted and restricted fertility.

Methods: In this prospective self before-after control study at a single University-based Infertility Center in Duesseldorf, Germany, a total of 25 male subjects were recruited, who were scheduled to receive their first vaccination against COVID-19 between January and August 2021. Semen samples were obtained before and after the first COVID-19 vaccination to perform an analysis of semen quality according to the 2010 World Health Organization guideline. Main outcome measures were ejaculate volume, sperm concentration, total sperm number, percentage of sperm motility and sperm morphology.

Results: There were no significant changes in sperm parameters before and after the vaccination.
Conclusion: Both, mRNA and vector-based COVID-19 vaccination had no short-term effect on sperm parameters. Therefore, an influence of COVID-19 vaccination on male fertility appears to be very unlikely.

FullText HTML FullText PDF DOI: 10.37871/jbres1558 CrossMark

Research Topics

Gynecology Reproductive Medicine Public Health

How to Cite

Philippos Edimiris*, Cornelius Doehmen, Lisa Mueller, Marcel Andree, Dunja Maria Baston-Buest, Sebastian Buest, Ortwin Adams, Jan-Steffen Kruessel and Alexandra Petra Bielfeld (2022). Vaccination with either mRNA or Vector-Based COVID-19 Vaccine has no Detectable Effect on Sperm Parameters. Journal of Biomedical Research & Environmental Sciences, 3(9). https://doi.org/10.37871/jbres1558

Article Information

JournalJournal of Biomedical Research & Environmental Sciences (JBRES)
ISSN2766-2276
DOI DOI 10.37871/jbres1558
Volume / IssueVol. 3, Issue 9
PublishedSeptember 22, 2022
Article TypeResearch Article
Pages1076-1081
LicenseCC BY 4.0 — Open Access
PublisherSciRes Literature LLC, Sheridan, WY, USA
LanguageEnglish
Creative Commons BY 4.0

Published under CC BY 4.0 — free to share, copy, adapt, and redistribute with attribution.

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