Brain and Nervous System Sciences
Section Editors
Adam Wiśniewski
Ashok Chakraborty
Atefeh Bakhtazad
Bernard G. Schreurs
Bulang Gao
Chen Lin
Dr. Mykola M. Salkov
Fiona Limanaqi
Hsien-Yuan Lane
HSIEN-YUAN LANE
Hsien-Yuan Lane
Kalliopi Megari
Lei Han
Mosab Shetiwy
MOSHIUR RAHMAN
Naznin Sultana
Premkumar Daivasikamani
Radha Chaube
Siying Song
Song-Yu Yang
Stephen D. Ginsberg
Vadim Belenky
William S Baek
Research Topics in this Section
Alzheimer's
Brain Disorders
19
Brain DisordersThese topics are filtered from our journals helping to discover the community within the widespread of multi-discip…
Brain Tumors
3
Brain TumorsThese topics are filtered from our journals helping to discover the community within the widespread of multi-disciplin…
Multiple Sclerosis
1
Multiple SclerosisThese topics are filtered from our journals helping to discover the community within the widespread of multi-dis…
Neurological Disorders
24
Neurological DisordersThese topics are filtered from our journals helping to discover the community within the widespread of multi…
Neurology
36
NeurologyThese topics are filtered from our journals helping to discover the community within the widespread of multi-disciplinary…
Neurooncology
3
NeurooncologyThese topics are filtered from our journals helping to discover the community within the widespread of multi-discipli…
Neurosurgery
10
NeurosurgeryThese topics are filtered from our journals helping to discover the community within the widespread of multi-disciplin…
Parkinson's Disease
Recent Articles
50 articles
Open Access
Research Article 14 Apr 2026
The Neurological Renaissance: Elucidating the Complex Relationship between Syphilis and Neurodegenerative Disorders in the Contemporary Era
The global resurgence of syphilis has coincided with increasing evidence of complex interactions between Treponema pallidum infection and neurological disorders, extending beyond classical neurosyphilis manifestations. T…
8 Views 52 Downloads
Open Access
Review Article 18 Feb 2026
From Brain Evidence to Neurorights: Rethinking Criminal Responsibility in the Age of Neurotechnology
The article, which raises never-before-bioethical and legal questions, is a consideration of the manner in which rapid advances in neurotechnology are reshaping criminal law. Neurotechnology is changing how we think abou…
23 Views 70 Downloads
Open Access
Observational Studies 05 Dec 2025
Integrating Serum Biomarkers and Genetic Polymorphisms for Alzheimer’s disease Risk Screening
Objective: Analyze the differences in the detection results of Alzheimer’s Disease (AD) serum biomarkers and the expression of APOE and SLCO1B1 genotypes, then construct an AD diagnostic model integrating serum biomark…
94 Views 75 Downloads
Open Access
Review Article 18 Oct 2025
Neurotoxicants on the Menu: Mapping the Link between Food Contaminants and Autism in African Children - A Scoping Review
Background: Autism Spectrum Disorder (ASD) is a growing neurodevelopmental concern in Africa, with environmental risk factors such as neurotoxic food contaminants believed to play a role in its prevalence among children.…
280 Views 77 Downloads
Open Access
Review Article 18 Oct 2025
A Comprehensive Review of Computational Modeling in Tumor and Brain Disorder with a Focus on Ablation Therapies
This review paper provides a comprehensive overview of computational modeling approaches applied to the study of tumors and brain disorders, with a particular focus on ablation therapies. We delve into the fundamental pr…
257 Views 73 Downloads
Open Access
Clinical Trials 23 Sep 2025
Detection of Human Cytomegalovirus DNA in Plasma from Patients with Brain Tumors Using a Sensitive qPCR Assay
Background: Human Cytomegalovirus (HCMV) has been detected in tissue samples from patients with glioblastoma, but its presence in blood has been less studied. Methods: In this prospective study, we analyzed the levels o…
88 Views 84 Downloads
Open Access
Case Report 27 Aug 2025
A Typical Neuroleptic Malignant Syndrome Presenting with Hyponatremia
Neuroleptic Malignant Syndrome (NMS) is a rare but potentially fatal neurological complication of medications affecting the central dopaminergic system, especially antipsychotic agents. According to one theory, decreased…
157 Views 88 Downloads
Open Access
Review Article 18 Aug 2025
AWAKEN Regenerative Intelligence - How Consciousness Evolution Guides the $115 Trillion Intergenerational Wealth Transfer toward Life-Serving AI-Governance
"The next “moonshot’ isn’t technological-it’s the leap from 5% to 100% human capacity of awakening “consciousness†for intergenerational well-beingâ€.We're living through a paradox of staggering potential an…
365 Views 82 Downloads
Open Access
Review Article 31 Jul 2025
Role of Cyclooxygenase-2 Inhibitors in Animal Models of Epilepsy: A Systematic Review
Background: The presence of recurrent seizures characterizes epilepsy, which is defined as a chronic disorder of the nervous system. It has recently been suggested that COX-2 inhibitors may offer protective neurotherapeu…
514 Views 105 Downloads
Open Access
Case Report 16 Jul 2025
Case Presentation Corticosteroids as the treatment of Left Hypoglossal Nerve Paralysis in a 35-Year-Old Man Following a Jiu Jitsu Training Maneuver
This case report describes a rare instance of isolated left hypoglossal nerve (cranial nerve XII) paralysis in a 35-year-old male following a jiu jitsu training session. The patient presented with acute-onset dysarthria …
697 Views 75 Downloads
Open Access
Review Article 16 Jun 2025
Analysis and Control of Alzheimers Disease Models
Millions of people are affected by Alzheimer's disease, which is a progressive neurodegenerative disorder. It is important to understand the progression dynamics of this disease to be able to minimize the damage that is …
249 Views 75 Downloads
Open Access
Review Article 27 Mar 2025
Pregnancy and Menieres Disease
Pregnancy is well known to cause further progression of the clinical symptoms of Ménière’s disease. However, mild low-tone hearing loss and ear fullness, similar to the hearing impairment of Ménière’s disease, is…
2,580 Views 120 Downloads
Open Access
Review Article 19 Mar 2025
Stewarding Regenerative Experience (RX): AI-Quantum for Humanity in Cognitive, Health and Well-being
As Artificial Intelligence (AI), quantum intelligence, and deep technologies advance rapidly, human cognitive flexibility, emotional resilience, and adaptability are experiencing a significant decline. AI excels in optim…
1,838 Views 93 Downloads
Open Access
Mini Review 15 Mar 2025
Can Ketamine Treat Schizophrenia?
NMDAR antagonists, such as memantine and ketamine, have demonstrated efficacy in treating neurodegenerative diseases and major depression. Our recent findings reveal that these antagonists significantly enhance 20S prote…
2,098 Views 102 Downloads
Open Access
Editorial 29 Dec 2024
Breaking Barriers in Brain Tumor Research: Glioblastoma Innovations and Open Science
473 Views 136 Downloads
Open Access
Case Series 09 Nov 2024
Impact of Deep Brain Stimulation on Addictive Behaviors A Case Series of Parkinsonians Patients
Deep brain stimulation of the Subthalamic Nucleus (STN-DBS) is a recognized treatment in Parkinson’s disease (PD), but knowledge is still limited regarding its possible impact on patients with Behavioral Addiction (BA)…
1,721 Views 117 Downloads
Open Access
Case Report 30 Sep 2024
Stroke as the First Sign of Heart Tumor What the Neurologist should know about Heart
Primary heart cancers are rare, but cancer metastases occur much more often, which is why they are diagnosed mainly in non-oncology departments. Approximately 85% of heart cancers are benign, with myxoma predominating [1…
184 Views 119 Downloads
Open Access
Research Article 11 Sep 2024
Reduced Number of Oligodendrocytes in the Cingulum in Schizophrenia: A Design-Based Stereology Study
Schizophrenia is a severe mental disorder with a neurodevelopmental origin whose pathophysiological processes are poorly understood. Magnetic resonance imaging studies have shown structural alterations, such as volume lo…
423 Views 108 Downloads 1 Citation
Open Access
Commentary 11 Sep 2024
Limitations of Current Treatment of Alzheimer’s Disease and Proposed Plan to Improve it
872 Views 119 Downloads
Open Access
Research Article 11 Jun 2024
Neurocognitive Impairment among HIV-Infected Participants on Methadone for IV-Heroin use in Yunnan, China Relates to AIDS Status and Depression Severity, not Patterns of Substance use
We used a comprehensive and culturally normed battery of Neurocognitive (NC) tests to evaluate NC impairment (NCI) in 406 adults with prior IV heroin use who were in a government-supervised methadone maintenance program …
366 Views 111 Downloads
Open Access
Editorial 08 Jun 2024
The Promise of Tumor Mutation Burden and Microenvironment as Biomarkers in Glioma Treatment
Gliomas, particularly high-grade gliomas like glioblastomas, represent some of the most formidable challenges in oncology. These brain tumors are notorious for their resistance to conventional therapies, including surger…
409 Views 103 Downloads
Open Access
Mini Review 17 Nov 2023
Ultrastructural Changes in Brain Tissue in Drug-Resistant Mesial Temporal Lobe Epilepsy in Humans: A Mini-Review
Epilepsy is a group of chronic neurological diseases of the brain characterized by a persistent predisposition to epileptic seizures, affecting more than 70 million people worldwide. Drug-resistance is a key problem in t…
462 Views 99 Downloads
Open Access
Case Report 22 May 2023
Sympathetic Sudomotor Ganglionopathy Following Envenomation from a Northern Australia Jellyfish Irukandji Syndrome
The oceans of northern Australia coastal beaches harbor numerous venomous jellyfish. Several species cause Irukandji Syndrome, a severe disorder (developing within an hour after a sting) consisting painful muscle cramps,…
1,012 Views 89 Downloads
Open Access
Case Report 04 May 2023
Electroconvulsive Therapy for the Anti-NMDA Receptor Encephalitis: A Case Report
Anti-NMDA encephalitis is a rare autoimmune disorder that affects the central nervous system. We report a case of a 22-year-old male patient with a history of prodromal flu-like symptoms followed by brief aggression epis…
851 Views 96 Downloads
Open Access
Case Series 27 Apr 2023
Heads or Tails: Incomplete Penetrance and Variable Expressivity at 15q11.2 Microdeletion (BP1-BP2)
Neurodevelopmental disorders are a group of pathologies with increased frequency in pediatric practice. During the last decade, genetic studies such as CGH arrays have aided in the search for genetic gains or losses that…
797 Views 89 Downloads
Open Access
Research Article 26 Apr 2023
miRNAs as Valuable Diagnostic Biomarkers in Patients with Multiple Sclerosis
Multiple Sclerosis (MS) is an autoimmune condition caused by chronic inflammation of central nervous system and demyelination of neurons. At present, microRNAs (miRNAs) are recognised as a diagnostic and prognostic indic…
1,099 Views 82 Downloads 3 Citations
Open Access
Review Article 22 Apr 2023
Association between Dietary Habits, Lifestyle and Migraine Attacks During Social Isolation in the COVID-19 Pandemic: A Systematic Review of Observational Studies
Eating habits and lifestyle were the areas of life most affected by the COVID-19 pandemic, especially in patients with migraine, whose triggers for their crises are related to these factors. Thus, the aim of this study w…
3,872 Views 107 Downloads 2 Citations
Open Access
Case Report 29 Mar 2023
Dural Tentorial Fistula of Bernasconi-Cassinari Artery, Two Case Reports: Supratentorial and Infratentorial
We report two rare and infrequent cases, one of a patient with a Cognard type V tentorial dural fistula diagnosed at the beginning as a trunk glioma in a patient with gait disturbance. And another with a Guillian Barré …
870 Views 107 Downloads
Open Access
Case Report 28 Feb 2023
Left Parietal Craniectomy in Osteosarcoma with a Collagen Matrix and Cement-Based Repair
For routine clinical practice, it is vital prior to surgery to plan the steps of the same as possible complications that may occur and how to resolve them. This case is of special interest for being a large tumor that du…
723 Views 111 Downloads
Open Access
Review Article 31 Jan 2023
Tumor Mutation Burden and Tumor Microenvironment as Biomarkers of Glioma Treatment Outcome and Prognosis: A Systematic Review and Meta-Analysis Protocol
Background: Gliomas are the most common solid malignant tumors of the brain; diffuse gliomas pose a remarkable conundrum on treatment strategy. WHO Grade IV (Glioblastomas) delineate a refractory resistance to treatment…
774 Views 123 Downloads
Open Access
Perspective 26 Dec 2022
Can Endomicroscopic Tissue Characterization be Combined with Deep Machine Learning to Support Neurosurgery?
Confocal Laser Endomicroscopy (CLE) is a new technique that is able to show cell structures during surgery. The interpretation of CLE data for tissue characterisation during brain tumour resection is challenging even amo…
458 Views 93 Downloads
Open Access
Short Communication 14 Oct 2022
Monkeypox and Immunosuppressed Neurological Patients: What can we Advise Vaccination in Multiple Sclerosis and Neuromyelitis Optica Patients?
Monkeypox is a zoonotic viral disease that was identified in 1958 in research monkeys that came from Singapore. It is an orthopoxvirus that belongs to the Poxviridae family [1]. This viral infection was restricted to Afr…
768 Views 67 Downloads 2 Citations
Open Access
Opinion 15 Sep 2022
Images of a Highly Metastatic Ependymoma of the Cauda
Images from a spinal ependymoma extending from twelfth thoracic to the third lumbar vertebral level will be discussed, together with the history and the final outcome of a highly metastatic neuroepithelial tumor. The you…
1,185 Views 66 Downloads
Open Access
Review Article 09 Sep 2022
Diagnosis and Treatment of Children Cerebral Palsy with Method Resonance Medicine
The article discusses two forms of resonance in medicine in the treatment of Children Cerebral Palsy. The first form is the destruction resonance. It is well known and we have used it to destroy, for example, tumors. The…
2,451 Views 72 Downloads 2 Citations
Open Access
Case Report 07 Sep 2022
A Neurodevelopmental Disorder with Intellectual Disability and Autism due to MAP7D3 Haploinsufficiency
We report on a young boy with a neurodevelopmental disorder who is a carrier of a novel frameshift mutation in gene MAP7D3 (MAP7 domain containing 3) of Xq26.3. The protein encoded by this gene belongs to the MAP7 (micro…
904 Views 59 Downloads 2 Citations
Open Access
Mini Review 29 Apr 2022
Post-COVID Syndrome During the COVID-19 Pandemic and the Impact of COVID-19 on the Brain
The review provides information on the classification, mechanisms of development of infection and multiple organ damage, as well as clinical manifestations of post-COVID syndrome (Post-СOVID Conditions, Long COVID, Post…
4,356 Views 94 Downloads
Open Access
Mini Review 28 Feb 2022
Neuroprotective Effects of Thiazolidine-4-Carboxylic Acid Derivatives on Memory Impairment and Neurodegeneration
Some studies have shown numerous biological activities of Thiazolidine derivatives, including neuroprotection. The production of inflammatory markers and Reactive Oxygen Species (ROS) plays a major role in nerve damage t…
2,291 Views 94 Downloads
Open Access
Review Article 26 Feb 2022
CNS Demyelination Diseases Following Exposure to Urban Air Pollution
Epidemiology findings show that exposure to urban air pollutants as a source of oxidative stress and neuroinflammation is associated with the Central Nervous System (CNS) demyelinating diseases, such as Multiple Sclerosi…
2,536 Views 90 Downloads 2 Citations
Open Access
Review Article 31 Jan 2022
Parkinsons Disease-Like Neuropathology and Phenotype Following Induction of Oxidative Stress and Inflammation in the Brain
Parkinson’s Disease (PD) is a neurodegenerative disorder characterized by motor deficits caused by the loss of dopaminergic neurons in the Substantia Nigra (SN) and Ventral Tegmental Area (VTA). However, clinical data …
2,103 Views 96 Downloads 1 Citation
Open Access
Opinion 04 Jan 2022
Assessment of Psychiatric Issues in Post-concussion Syndrome
The term "Post-Concussion Syndrome" (PCS) refers to a group of non-specific symptoms that occur after a concussion or Mild Traumatic Brain Injury (MTBI) and last longer than expected. Headaches, weariness, vertigo/dizzin…
1,615 Views 107 Downloads
Open Access
Review Article 30 Nov 2021
Alzheimers Disease-Like Neuropathology Following Exposure to Ambient Noise
Many factors play a role in the risk of dementia, including the environment. Widespread and significant worldwide exposure to noise, the severity of related health consequences, and the limited tools available to the pub…
1,459 Views 71 Downloads 8 Citations
Open Access
Case Report 30 Oct 2021
Fovilles Syndrome a Case to Remember Case Report
The Foville’s Syndrome is a rare clinical feature of stroke or brain hemorrhage. This is very rare brain stem syndrome and only few cases have been reported worldwide. A case of Foville's syndrome secondary to infarcti…
3,706 Views 75 Downloads
Open Access
Review Article 30 Oct 2021
Integrative Review Verification of the Influence of Atrazine Exposure on Behavioral, Neurochemical and Parkinsons Disease Disorders
Herbicides represent the largest portion of pesticides used both worldwide and in Brazil. Many of these compounds are applied on a large scale in native forests and in urban and industrial water environments, including a…
1,150 Views 75 Downloads 3 Citations
Open Access
Review Article 26 Oct 2021
Exposure to Air Pollution Nanoparticles: Oxidative Stress and Neuroinflammation
Urban air pollutants exposure is known as a source of neuroinflammation and oxidative stress that causes the Central Nervous System (CNS) and neuropathology disease. Transition metals, Particulate Matter (PM), including …
3,739 Views 69 Downloads 15 Citations
Open Access
Review Article 21 Oct 2021
Exposure to Ambient Ultra-Fine Particles and Stroke
Stroke is one of the main causes of death attributed to air pollution. Significant research has now shown that urban air pollutants exposure has been established as a source of neuroinflammation and oxidative stress that…
1,123 Views 60 Downloads 9 Citations
Open Access
Letter to Editor 29 Sep 2021
Artificial Intelligence in Cranial Surgeries
Artificial Intelligence (AI) is a broad phrase that refers to any machine’s activity that would otherwise need human intellect.Recent technological advancements have closed the gap between human and machines, allowing …
1,229 Views 79 Downloads 1 Citation
Open Access
Review Article 25 Aug 2021
Guillain-Barre Syndrome: Review and Summary
Guillain-Barré Syndrome is a life-threatening, demyelinating, autoimmune condition in which the body’s immune system attacks the myelin of the peripheral nervous system. Guillain-Barré Syndrome is characterized by as…
3,327 Views 103 Downloads
Open Access
Research Article 13 Aug 2021
Effects of Heavy Metal Toxicity on Anxiety Disorder
Background: Several heavy metals are found naturally in the earth crust and are exploited for various industrial and economic purposes. Among these heavy metals, a few have impact on the human body. Though some of these …
9,506 Views 125 Downloads 1 Citation
Open Access
Research Article 27 Jul 2021
Research Progress in the Repair of Peripheral Nerve Injury with Adipose-Derived Stem Cell Exosomes
The repair of peripheral nerve injury has always been a difficult clinical problem. Although a variety of treatment methods are available in clinical practice, their efficacy is limited. In recent years, the components c…
13 Views 122 Downloads
Open Access
Research Article 15 Jul 2021
Potential Clinical Benefits of Combination of Black Seed, Licorice and Turmeric Supplements within the Treatment Regimens of Bells Palsy
Bell’s palsy can be considered as one of the most resistant and idiopathic neuromuscular facial diseases. It has not any specific effective treatments up to date in 2021. The aim of this article is to introduce this ne…
7,669 Views 151 Downloads