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Parkinson's Disease (PD) is the second most frequently observed slowly progressive neurodegenerative disease after Alzheimer's. Although dopamine replacement remains an essential component of treatment, the point at which dyskinetic movements and motor fluctuations begin may demand a number of different approaches, bot…

It is important to understand the interplay of epigenetic changes, exercise and nutrition associated with the development of obesity and type-2 diabetes because it offers insights into how environment and lifestyle factors can influence gene expression without altering the genetic code. This knowledge can lead to the d…

In Joiner’s Interpersonal Theory of Suicide, those who are planning to die by suicide have to overcome their fear of death in addition to acquiring the capacity for self-harm. The present study sought to examine this proposal in a sample of 1,145 university students in China. Those who had planned to dye by suicide i…

Clinical studies suggest that regular and moderate physical activity has a positive influence on the general health of individuals, including neuro-psychological well-being. In particular, physical exercise can improve memory storage and learning ability, thus reducing the risk of developing serious neurodegenerative d…

A quarter of a century after establishment of inhibitory effect of blue light on growth of cancer cells, many aspects of mechanism of photophysical and photochemical processes underlying the effect of above physical factor have been quite well studied. However, the most controversial question remains about molecules-ac…

We present in this study that one Oxysterol (OS) within the lipid fraction of the isolated epidermal gel released from freshly caught catfish from the Arabian Gulf (Arius bilineatus, Val.) potently and selectively inhibits the collagen-evoked aggregation of human platelets in vitro. This cholesterol metabolite, identif…

Adults with Congenital Heart Disease (ACHD) are a constantly growing population that often presents significant challenges and requires a multidisciplinary approach. Therapeutic decisions must balance potential benefits and procedural risks, especially in young patients. Interventional cardiology offers treatments that…

The screening of exosomes from various sources reveals that potato-derived exosomes exhibit the most significant anti-inflammatory activity, as demonstrated by RT-PCR analyses of Tumor Necrosis Factor expression in exosome-treated HaCaT cells. Exosomes extracted from potatoes are nanoparticles averaging 66 nm in diamet…

The high adsorption capacities of Polyaniline (PANI) and Carbon Nanotubes (CNTs) for heavy metals, combined with the synergistic effect of Magnesium Oxide (MgO), were leveraged to develop a modified Glassy Carbon Electrode (GCE), referred to as MgO@PANI@CNT/GCE, for the accurate detection of Cd²+ and Pb²⁺ ions. A c…

This study, based on TRIZ theory, explored the design and manufacturing process of wooden low stools. The results showed that the systematic approach and innovative tools provided by TRIZ theory effectively resolved various contradictions encountered in the design of wooden low stools, thereby enhancing the product's p…

Osteosarcoma, a primary malignant bone tumor, predominantly affects children and young adults, with a high incidence during puberty. Early diagnosis is critical due to the rapid tumor growth. Neoadjuvant chemotherapy has improved outcomes slightly, but prognosis remains poor in South Asia. Socioeconomic challenges and …

Lichens are a rich source of diverse secondary metabolites, with depsides playing a crucial role in their biological properties. Atranorin, a prominent depside, has been widely studied due to its significant pharmacological effects. This review explores the biosynthesis of atranorin, elucidates its molecular structure,…

IgG4-RD is a chronic fibro inflammatory disease characterized by a significant elevation of serum IgG4 concentration and marked infiltration of IgG4-positive plasma cells in the affected organs. A dense lymphoplasmacytic infiltrate and the formation of ectopic lymphoid structures are characteristic histopathological fi…