All Articles

Traditional Chinese Medicine (TCM), including herbal remedies and animal secretions like HuaChansu, also called Cinobufacini, has gained attention for its therapeutic efficacy in cancer treatment. HuaChansu, extracted from the skin of toads from the genus Bufo, has been used traditionally for various diseases and recen…

Xanthatin possesses anticancer activities through its effect on cancer cell proliferation, apoptosis and metastasis In vitro and In vivo. Here, we described the isolation procedure, characterization and In vitro biological evaluation of the active metabolite xanthatin from Xanthium strumarium grown in Cuba. From the ae…

Thermodynamics is crucial for optimizing drug synthesis, developing pharmaceutical formulations and ensuring their stability, effectiveness and safety. The thermochemical properties of active pharmaceutical ingredients with the common biphenyl motif (RS-Flurbiprofen, Diflunisal, Fenbufen and Biprofen) available in the …

Prophylaxis by stable iodine “KI 65 mg, breakable tablet” is a pharmacological countermeasure of radiological protection adapted for the prevention of thyroid cancer after exposure to radioactive iodine. A first modification of the marketing authorization of “KI 65 mg, breakable tablet” for repeated prophylaxis…

As the demand for secure and efficient data sharing in healthcare continues to grow, there is a pressing need for innovative solutions that ensure data privacy, integrity, and accessibility in multiple institutions. This study proposes a unified framework that integrates three cutting-edge technologies, federated learn…

Schizophrenia is a severe mental disorder with a neurodevelopmental origin whose pathophysiological processes are poorly understood. Magnetic resonance imaging studies have shown structural alterations, such as volume loss in the temporal lobe, including the hippocampus and amygdala, thalamus, and frontal and temporal …

The increasing attention in academic and industry research on per and Poly-Fluoroalkyl compounds (PFAS) in the environment is a result of growing concern. If PFAS are exposed to human health, they are also known to be dangerous. Utilizing leftover lignocellulosic biomass, biochar is a pyrolytic material that can be use…

Atypical fluid retention is an uncommon side effect of imatinib therapy. This case report describes ascites that developed post-Abdominal Aortic Aneurysm (AAA) repair in a man on imatinib for Chronic Myeloid Leukemia (CML), and only resolved on cessation of imatinib therapy.…

Anticoagulant medications, particularly Vitamin K Antagonists (VKAs), are essential for managing thrombotic conditions but can cause severe side effects such as spontaneous hematomas. This case report describes a 69-year-old woman on VKA therapy who developed a large right breast hematoma. Immediate suspension of VKA, …

As the demand for minimally invasive aesthetic treatments increases, the need for a structured individualized facial analysis is becoming more and more evident. This article therefore presents FILLMED’s 6-step matrix, a holistic six-step guide for facial assessment prior to aesthetic treatments aiming to optimize the…

Microplastics (MPs) have aroused a global health concern and their coexistence with antibiotics is inevitable. However, how MPs would affect the bioaccumulation and risks of antibiotics in humans remains poorly understood. In this study, we reviewed several articles that examined the abundance and expression changes of…