Botanical innovations hold unprecedented potential to address pressing global challenges in human health and environmental sustainability. However, a significant disconnect persists between scientific advancement and public understanding, often termed 'plant awareness disparity,' limiting the societal impact of these innovations. This comprehensive review examines the critical role of strategic health communication in bridging this gap. It synthesizes interdisciplinary literature to provide a roadmap for enhancing public engagement, trust, and informed decision-making regarding plant science. The review is structured to first establish the historical and scientific context of plant-based solutions, then analyze communication theories and barriers, and finally propose evidence-based strategies and a future agenda. Our analysis reveals that effective communication must move beyond simply transmitting information. It requires: (1) audience-centric message tailoring that respects cultural beliefs and traditional knowledge; (2) savvy navigation of the digital ecosystem to amplify credible science and combat misinformation; and (3) a foundational commitment to building scientific literacy and public trust through transparency and participatory dialogue. We identify major barriers, including technical complexity, cultural misalignment, and the pervasive spread of digital misinformation. The successful integration of botanical innovations into society is contingent upon a paradigm shift in science communication. By adopting a strategic, multi-dimensional approach that is inclusive, digitally agile, and trust-building, the plant science community can foster a plant-literate society. This is a prerequisite for unlocking the full potential of plant science to contribute to the health of both people and the planet, thereby achieving key Sustainable Development Goals (SDGs).