Background: As the world witnessed the outbreak of coronavirus illness 2019 (COVID-19), a disorder developed as a result of a novel coronavirus, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), increasing genetics with healthcare evidence suggest a corresponding leadership to SARS as well as the Middle East Respiratory Syndrome (MERS).

Aim: The aim of this review is to highlight Immune response of human body toward COVID-19.

Materials and methods: This was a narrative review. A comprehensive literature search was done using PubMed, Google Scholar, Scopus, and EMBASE using the keywords, Immune Response; COVID-19; Vaccination; SARS-Cov-2; ACE2; Coronavirus; MERS.

Results: A flow of viral components passes to the body by means of nostrils, mouth and eyes. SARS-CoV-2 is in a position to continue to become unnoticed extended than numerous influenza or coronaviruses. Its proteins can accomplish entry by unlocking the Angiotensin-Converting Enzyme 2 (ACE2) protein in the lung cells; viruses also possess antigens furthermore recognize that these are what cries the immunity into movement via making antibodies. Investigators demonstrate an extensive variety of immune cells respond to COVID-19 along with valuable source retrieval, discovering that might want to notify the manufacturing of a viable vaccination.

Conclusion: The body's natural response to a viral infection is a non-invasive intrinsic response in which macrophages, neutrophils, and dendritic cells limit the virus's progression and may even prevent it by multiplying symptoms. This non-invasive solution is accompanied by an elastic response in which the body produces radicals that primarily adjust to the herpes virus.