Antibacterial Effect of Indian Gooseberry (Phyllanthus emblica L.) Extract Against ESBL Producing Multi-Drug Resistant Bacteria

Vemula Sarojamma; Eedlapalli Siddhartha; Ramakrishna Vadde*

Vemula Sarojamma, Eedlapalli Siddhartha and Ramakrishna Vadde*

Volume5-Issue2
Dates: Received: 2024-01-12 | Accepted: 2024-02-29 | Published: 2024-02-29
Pages: 227-232

Abstract

The most celebrating fruit in Indian traditional medicine Ayurveda is the Indian gooseberry also known as amla fruit, used the prevention of numerous diseases. No reports are available on the prevention of ESBL produced MDR bacteria has lead us to investigate amla’s bioactive compounds (total phenolics, flavonoids, tannins) and their antioxidant and antibacterial activities against MDR bacteria (E coli, P aeruginosa, S aureus, K pneumoniae, H influenza, S typhi). Higher levels of phenolics with elevated levels of antioxidant activities were noticed in amla extracts and also scavenged all types of free radicals including DPPH, ABTS, -OH, H2O2, and superoxide radicals at lowest concentrations. Disc diffusion method was used for determination of antimicrobial activities of extracts and seen temperate growth inhibition against MDR bacteria as compared to control drug, cefotaxime. The results concluded that Indian gooseberry inhibited the growth of ESBL produced MDR bacteria with high levels of phenolics and their antioxidant potential.

FullText HTML FullText PDF DOI: 10.37871/jbres1886

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How to cite this article

Sarojamma V, Siddhartha E, Vadde R. Antibacterial Effect of Indian Gooseberry (Phyllanthus emblica L.) Extract Against ESBL Producing Multi-Drug Resistant Bacteria. J Biomed Res Environ Sci. 2024 Feb 29; 5(2): 227-232. doi: 10.37871/jbres1886, Article ID: JBRES1886, Available at: https://www.jelsciences.com/articles/jbres1886.pdf

Subject area(s)

Pharmaceutica Analytica Acta

Pharmacology

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